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MedUni Vienna researchers discover possible trigger of chronic inflammatory bowel disease

As the cause of chronic inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms.

10 Jan 2024

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

Researchers developed the NOVA algorithm to systematically analyze bacterial isolates unidentified using traditional methods such as matrix-assisted laser desorption ionization-time of flight mass spectrometry and partial 16S rRNA gene sequencing using whole genome sequencing.

10 Jan 2024

Protein secrets revealed: Single-molecule spectroscopy ushers in era of personalized medicine

Infrared vibrational spectrum of a single protein is observed using advanced measurement techniques based on near-field optical microscopy.

9 Jan 2024

Bottled water harbors a quarter of a million tiny plastic particles, posing unknown health risks

Researchers discovered an average of 240,000 nanoplastic particles per liter in bottled water, far exceeding previous estimates, raising concerns about their potential to invade human cells and impact health due to their ability to pass through biological barriers.

8 Jan 2024

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane.

8 Jan 2024

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.

4 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders.

4 Jan 2024

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

Recent studies by Zampaloni et al. and Pahil et al. published in the journal Nature describe a novel method of inhibiting the growth of Gram-negative bacteria such as Acinetobacter using antibiotics consisting of macrocyclic peptides that target the bacterial protein bridge machinery that transports lipopolysaccharides from the cytoplasm to the outer membrane.

4 Jan 2024

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Study explores the potential of EZH2 inhibitors GSK126 and Tazemetostat in stimulating β-cell regeneration from pancreatic ductal progenitor cells, offering a novel therapeutic approach for Type 1 Diabetes.

3 Jan 2024

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.

3 Jan 2024

Cytonemes: The "express subways" of the developing nervous system

St. Jude Children's Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development.

3 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

Cadmium linked to DNA damage and morphological changes caused by particulate matter

Particulate matter causes health problems for those who inhale the fine droplets and particles, but the chemical composition of the mixture matters - and can vary widely across space and time.

28 Dec 2023

Research reveals how "forever chemicals" damage DNA at the molecular level

Recent research published in the journal Eco-Environment & Health (Volume 2, 2023) reveals groundbreaking insights into how typical PFAAs accelerate the degradation of DNA.

26 Dec 2023

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

St. Jude researchers reveal structure of Parkinson's-linked proteins

Scientists at St. Jude Children's Research Hospital revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases.

21 Dec 2023

Early embryo DNA replication program reveals unexpected flexibility

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next.

20 Dec 2023

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

19 Dec 2023

Microfluidic chip design optimizes cancer exosome detection

Cancer, a leading cause of death globally, releases TDEs, tiny vesicles containing crucial bioactive components.

19 Dec 2023

Microscopy News and Research

MedUni Vienna researchers discover possible trigger of chronic inflammatory bowel disease

New algorithm proves to be a powerful tool for detection and identification of novel bacterial organisms

Protein secrets revealed: Single-molecule spectroscopy ushers in era of personalized medicine

Bottled water harbors a quarter of a million tiny plastic particles, posing unknown health risks

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Unmasking the persistent threats of long-COVID's pulmonary sequelae

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

New compound effective against bacterial species resistant to multiple classes of existing antibiotics

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

Cytonemes: The "express subways" of the developing nervous system

How immune cells shape our earliest breaths

Cadmium linked to DNA damage and morphological changes caused by particulate matter

Research reveals how "forever chemicals" damage DNA at the molecular level

Shedding new light on the hidden organization of the cytoplasm

St. Jude researchers reveal structure of Parkinson's-linked proteins

Early embryo DNA replication program reveals unexpected flexibility

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Microfluidic chip design optimizes cancer exosome detection

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