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Novel antibody shows promise for pain relief in peripheral nerves

Cell surface proteins play a crucial role in cell communication and in sensing changes in the extracellular environment.

9 Oct 2024

Vagus nerve stimulation enhances perceptual learning in mice

Just as a musician can train to more sharply distinguish subtle differences in pitch, mammals can improve their ability to interpret hearing, vision, and other senses with practice.

9 Oct 2024

Tiny molecule offers hope in reducing opioid side effects

Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression.

9 Oct 2024

Brainstem inflammation may explain long Covid symptoms

Damage to the brainstem – the brain's 'control center' – is behind long-lasting physical and psychiatric effects of severe Covid-19 infection, a study suggests.

8 Oct 2024

Understanding behavioral changes in early dementia

When most people think of dementia, including Alzheimer's disease, they probably think of memory loss first.

7 Oct 2024

Exploring the venomous potential of marine crustaceans for drug development

Many animals use venoms for self-defense or hunting. The components of such venom, known as toxins, interfere with various physiological processes - which is also the reason why they are so interesting for the development of new pharmacological agents.

4 Oct 2024

Identical twins study uncovers insights into multiple sclerosis mechanisms

Multiple sclerosis (MS) is a chronic inflammatory disease in which the immune system attacks the central nervous system.

4 Oct 2024

Researchers unveil complete neuronal map of fruit fly brain

Researchers map the whole brain of Drosophila melanogaster, or the fruit fly, which comprises about 140,000 neurons and over 50 million synapses.

4 Oct 2024

Study paves way to more efficient non-addictive treatment for chronic pain

Researchers at Karolinska Institutet in Sweden have developed a new comprehensive mapping of genetic activity for understanding the causes of chronic pain.

4 Oct 2024

New study could lead to a more potent treatment option for multiple sclerosis

Multiple Sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer around nerve cells, known as the myelin sheath.

2 Oct 2024

The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistance

A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors."

1 Oct 2024

High magnesium levels drive higher mortality in sepsis patients

Study identifies high serum magnesium levels as a significant factor associated with increased mortality in sepsis patients, demonstrating a dose-response relationship across diverse patient cohorts. It highlights magnesium as a potential marker for risk stratification in sepsis.

30 Sep 2024

Defective DNA repair mechanism linked to Huntington's disease progression

Researchers with McMaster University have discovered that the protein mutated in patients with Huntington's Disease doesn't repair DNA as intended, impacting the ability of brain cells to heal themselves.

27 Sep 2024

New insights into serine hydroxymethyltransferase aid cancer drug design

In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers.

26 Sep 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024