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Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

MIT researchers design new sensor to distinguish between viral and bacterial pneumonia

Many different types of bacteria and viruses can cause pneumonia, but there is no easy way to determine which microbe is causing a particular patient's illness.

13 Jun 2022

Evosep One enables robust, high throughput, single cell proteomics

Today, at the 70th Conference on Mass Spectrometry and Allied Topics, Evosep demonstrates new applications for standardization of high throughput single cell proteomics, higher throughput clinical analysis, and improved diabetes monitoring.

From Evosep 13 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Core body temperature increases host resistance to influenza virus and SARS-CoV-2 infection

A recent article posted to the Research Square* preprint server demonstrated that high body temperature elevates gut microbiota-reliant host resistance against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A viral infection.

10 Jun 2022

USA–Japan Workshop participants present cutting-edge research on biomarkers for early detection of cancer

Successful treatment of cancer frequently depends on early detection. However, many cancers are detected late, often after metastasizing to other sites.

9 Jun 2022

Study reveals inaccurate label claims on unregulated CBD products

Researchers determine the CBD content in various products and compare it to their label claims.

8 Jun 2022

Electronic nose detects SARS-CoV-2 from breath

Researchers discuss the development of an electronic nose device for the detection of SARS-CoV-2.

8 Jun 2022

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

A recent article illustrated the structural and biochemical characteristics of the processing of SARS-CoV-2 polyproteins by Mpro.

1 Jun 2022

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

Researchers compared the performance of a highly multiplexed mass spectrometry-based commercial assay to identify SARS-CoV-2 variants.

31 May 2022

The pineapple-derived jacalin-related lectin as a potential anti-SARS-CoV-2 agent

Scientists demonstrated that the pineapple-derived jacalin-related lectin (AcmJRL/AnLec) could be an anti-SARS-CoV-2 agent.

31 May 2022

Researchers identify the genetic causes of three mitochondrial diseases using new approach

When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, and vision problems.

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Researchers explored factors affecting substrate selection by the SARS-CoV-2 replicase.

24 May 2022

Deep visual proteomics is redefining cancer diagnostics

In a recent study published in the journal Nature Biotechnology, researchers introduced deep visual proteomics (DVP), an amalgamation of artificial intelligence (AI) for image analysis and mass spectrometry (MS) for proteomic profiling of biological samples.

22 May 2022

Natural immunity weak and short-lived in unvaccinated after Omicron infection

In a recent study posted to the journal Nature, researchers showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection without SARS-CoV-2 vaccination conferred poor cross-variant neutralizing capacities.

20 May 2022

Small cell lung cancer subtypes respond differently to chemotherapeutics and targeted drugs

Small cell lung cancer (SCLC) is a malignant disease associated with a particularly high mortality rate. According to a new multicenter study led by MedUni Vienna and conducted in collaboration with researchers from the Czech Republic, Hungary, Slovenia, Sweden and the United States, SCLC can be divided into several subgroups in terms of clinical behavior.

17 May 2022

Spectrometry News and Research

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

MIT researchers design new sensor to distinguish between viral and bacterial pneumonia

Evosep One enables robust, high throughput, single cell proteomics

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Core body temperature increases host resistance to influenza virus and SARS-CoV-2 infection

USA–Japan Workshop participants present cutting-edge research on biomarkers for early detection of cancer

Study reveals inaccurate label claims on unregulated CBD products

Electronic nose detects SARS-CoV-2 from breath

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

The pineapple-derived jacalin-related lectin as a potential anti-SARS-CoV-2 agent

Researchers identify the genetic causes of three mitochondrial diseases using new approach

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Deep visual proteomics is redefining cancer diagnostics

Natural immunity weak and short-lived in unvaccinated after Omicron infection

Small cell lung cancer subtypes respond differently to chemotherapeutics and targeted drugs

Blood adenosine levels positively correlate to the white matter lesions in very low birth weight premature infants

Researchers identify compounds from Aspergillus that may be effective against SARS-CoV-2

Enzyme discovery offers new way to regulate cell death process for inflammatory diseases

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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