Genes News and Research

RSS

Researchers discover new functions of key cellular machine in cancer

Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers.

19 Nov 2020

Researchers identify CLCN6 as disease gene for severe lysosomal neurodegenerative disorder

A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and the Max Delbrück Center für Molekulare Medizin, together with an international team of researchers, have now analyzed the effect of a point mutation that was found in three unrelated affected children.

19 Nov 2020

Researchers uncover potential new target to fight inflammatory diseases

An international team of researchers have uncovered a drug-like compound that blocks a crucial inflammatory pathway, potentially paving the way for a new treatment for a host of diseases - including COVID-19.

19 Nov 2020

Researchers use bioinformatics methods to identify key genes in dilated cardiomyopathy

In a new publication from Cardiovascular Innovations and Applications, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Shantou, China consider the importance of mitochondrial-related genes in dilated cardiomyopathy.

19 Nov 2020

Study describes the early evolution of oral poliovirus vaccine

While the world reels from the spread of SARS-CoV2, the new coronavirus behind COVID-19, a much older and previously feared scourge--poliovirus--is close to being completely eradicated.

19 Nov 2020

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Organ and stem cell transplants are proven and frequently used methods in everyday modern clinical practice. However, even when performed regularly in specialized centers, some patients still experience a number of serious complications afterward.

19 Nov 2020

Research on genetic heart disease uncovers new mechanism for heart failure

Research on genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy.

19 Nov 2020

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.

19 Nov 2020

Decades of research into racial, ethnic health disparities fail to resolve disproportionate health outcomes

When it comes to understanding why children from non-white race groups have such poor health outcomes compared with their white counterparts, it's time for researchers to look beyond their genes and delve deeper into social factors, according to a commentary published today in the journal Pediatrics.

19 Nov 2020

NIH project aims to maximize efficiency of AAV platform for gene therapy

Maximizing the efficiency of the adeno-associated virus (AAV) platform for gene therapy is the aim of a new pilot project of the National Institutes of Health (NIH).

19 Nov 2020

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

18 Nov 2020

Researchers use single-cell analysis to assess effects of aging on mice’s egg cells

Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to reduced developmental competence.

18 Nov 2020

Study provides new insight into the formation of neural crest cells

Last year, researchers at the University of California, Riverside, identified the early origins of neural crest cells -- embryonic cells in vertebrates that travel throughout the body and generate many cell types -- in chick embryos.

18 Nov 2020

UTHSC and Regeneron partner to advance precision medicine

The University of Tennessee Health Science Center has entered into an agreement with the Regeneron Genetics Center, a subsidiary of Regeneron Pharmaceuticals, Inc., for the company to sequence DNA that has been voluntarily collected and stored as part of a biorepository initiative UTHSC is building in collaboration with its partner teaching hospitals.

18 Nov 2020

Ancient East Asian peoples may have adapted to coronavirus-like epidemic up to 25,000 years ago

A new study by researchers at the University of Adelaide and Australian National University in Australia and the University of Arizona in the US shows that an ancient coronavirus-like epidemic drove the adaptation of East Asian peoples from 25,000 to 5,000 years ago.

18 Nov 2020

Study: e-cigarette users have increased susceptibility to flu, COVID-19

In a controlled study of smokers, nonsmokers, and e-cigarette users, University of North Carolina School of Medicine researchers found that e-cigarette users exhibited significantly altered immune responses to a model of influenza virus infection, suggesting increased susceptibility to disease.

18 Nov 2020

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Researchers affiliated with the Center for Cell-Based Therapy in Ribeirão Preto, Brazil, have identified for the first time a non-hereditary mutation in blood cells from a patient with GATA2 deficiency, a rare autosomal disease caused by inherited mutations in the gene that encodes GATA-binding protein 2 (GATA2).

17 Nov 2020

Genes News and Research

Researchers discover new functions of key cellular machine in cancer

Researchers identify CLCN6 as disease gene for severe lysosomal neurodegenerative disorder

Researchers uncover potential new target to fight inflammatory diseases

Researchers use bioinformatics methods to identify key genes in dilated cardiomyopathy

Study describes the early evolution of oral poliovirus vaccine

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Research on genetic heart disease uncovers new mechanism for heart failure

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Decades of research into racial, ethnic health disparities fail to resolve disproportionate health outcomes

NIH project aims to maximize efficiency of AAV platform for gene therapy

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

Researchers use single-cell analysis to assess effects of aging on mice’s egg cells

Study provides new insight into the formation of neural crest cells

UTHSC and Regeneron partner to advance precision medicine

Ancient East Asian peoples may have adapted to coronavirus-like epidemic up to 25,000 years ago

Study: e-cigarette users have increased susceptibility to flu, COVID-19

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Two-thirds of older Americans would not seek treatment for depression, new poll shows

Analysis highlights the economic and health consequences of UTI superbugs in Australia

Scientists reveal how genetically modified organisms can help mitigate climate change

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics