Protein C News and Research

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The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Influence of chr12q24.13 domain on COVID-19 severity

Researchers evaluated the probable impact of the chr12q24.13 domain on the outcomes of laboratory-validated SARS-CoV-2 infection.

19 Jul 2022

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

Should siRNA-based antivirals be added to the COVID toolbox?

A recent study reviewed the existing treatment modalities, including vaccines and antivirals, for SARS-CoV-2 infection.

19 Jul 2022

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

18 Jul 2022

Researchers find link between brain protein and increased vulnerability to neurodegeneration in epilepsy patients

A team of Florida State University College of Medicine researchers has found a link between a specific protein in the brain and increased vulnerability to neurodegeneration for individuals with temporal lobe epilepsy (TLE).

18 Jul 2022

Hospitalized COVID-19 patients with high blood viscosity have greater risk of death

Patients hospitalized with COVID-19 with high estimated blood viscosity are at higher risk of death from complications. High blood viscosity impairs flow to small vessels and increases the risk of blood clots. This measure of blood thickness can be used as a predictor of mortality.

18 Jul 2022

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

18 Jul 2022

DNA may act as nutritional source for E. coli

Findings of a new experiment could be helpful in understanding how DNA acts as a nutrient for gut bacteria, and its impact on the health of the host.

18 Jul 2022

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders.

18 Jul 2022

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive.

18 Jul 2022

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

Researchers showed that the SARS-CoV-2 nucleocapsid (N) and spike (S) proteins did not activate γδ T cells and dendritic cells (DCs).

18 Jul 2022

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Researchers evaluated the activity of nitazoxanide against human coronaviruses (HCoVs).

18 Jul 2022

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Researchers screened bacterial mucosal vaccine vectors from 2015 to the present to identify a promising candidate to present SARS-CoV-2 spike protein or its fragments.

18 Jul 2022

Researchers develop a rapid, specific, and accurate RT-qPCR-based method to detect and distinguish between Omicron sublineages

Researchers developed a novel, rapid and accurate qRT-PCR-based method to detect Omicron sublineages BA.1/BA.1.1 and BA.2 in patient samples.

18 Jul 2022

The role of FTIR in protein analysis and biomedical applications

Professor Dr. Werner Mantele is the Professor of Biophysics at Goethe University and Frankfurt University. With over 30 years of experience with spectroscopy, Dr. Mantele is an internationally-recognized expert in the analysis and detection of molecules.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 18 Jul 2022

Protein C News and Research

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Influence of chr12q24.13 domain on COVID-19 severity

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Should siRNA-based antivirals be added to the COVID toolbox?

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Researchers find link between brain protein and increased vulnerability to neurodegeneration in epilepsy patients

Hospitalized COVID-19 patients with high blood viscosity have greater risk of death

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

DNA may act as nutritional source for E. coli

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Researchers develop a rapid, specific, and accurate RT-qPCR-based method to detect and distinguish between Omicron sublineages

The role of FTIR in protein analysis and biomedical applications

Cytokine-based cancer immunotherapy: current progress and future prospects

Study shows that older adults can generate robust, long-lived memory against SARS-CoV-2 following infection

Novel nanoligomer approach to treat severe COVID-19

Study results encourage SARS-CoV-2–infected mothers breastfeed to protect infants from COVID

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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