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Physical activity effective in reducing sclerostin in premenopausal women

A study to be published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM) suggests that physical activity for premenopausal women is very effective in reducing sclerostin-a known inhibitor of bone formation. In addition, physical training enhances IGF-1levels, which have a very positive effect on bone formation.

16 Aug 2012

Therapeutic breaks for prostate cancer patients

Men with advanced prostate cancer receiving androgen-deprivation therapy may be better off being treated intermittently rather than on a continuous basis, show study findings.

15 Aug 2012

PPMC earns Gold Seal of Approval for hip and knee joint replacement services

Penn Presbyterian Medical Center (PPMC) has earned the Gold Seal of Approval- from The Joint Commission for its hip and knee joint replacement services. PPMC's certification is the first of its kind for Penn Medicine, and demonstrates the hospital's high level of compliance with The Joint Commission's national standards for health care quality and safety.

15 Aug 2012

Proteonomix receives FDA approval to commence UMK-121 Phase 1 trial in end-stage liver disease

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today announced that the U.S. Food and Drug Administration (FDA) has granted permission to the Company to initiate a Phase 1 clinical trial with its mobilization technology UMK-121.

15 Aug 2012

Longer, conical miniscrews most successful for orthodontic anchorage

The length and shape of miniscrew implants used for orthodontic anchorage has an effect on their success, with longer, and conical rather than cylindrical screws significantly associated with success, report Italian researchers.

13 Aug 2012

Endocrine Society revises clinical practice guideline for management of thyroid dysfunction

The Endocrine Society has made revisions to its 2007 Clinical Practice Guideline (CPG) for management of thyroid disease during pregnancy and postpartum. The CPG provides recommendations for diagnosis and treatment of patients with thyroid-related medical issues just before and during pregnancy and in the postpartum interval.

12 Aug 2012

Combination of novel drug therapy and PSA test can effectively detect prostate cancer

Researchers have successfully developed and tested a new prostate cancer screening method that uses the combined power of a novel drug therapy and changes in PSA levels over time to identify men with a high PSA who are more likely to have aggressive prostate cancer despite negative biopsies.

12 Aug 2012

Promising stem cell therapy may prevent osteoarthritis after joint injury

Duke researchers may have found a promising stem cell therapy for preventing osteoarthritis after a joint injury.

10 Aug 2012

FDA approved drug to treat Ph- acute lymphoblastic leukemia

The U.S. Food and Drug Administration today approved Marqibo (vincristine sulfate liposome injection) to treat adults with a rare type of leukemia called Philadelphia chromosome negative (Ph-) acute lymphoblastic leukemia (ALL). ALL is a rapidly progressing form of blood and bone marrow cancer that is more commonly diagnosed in children than adults.

10 Aug 2012

Longer looks: Waking up to the need for sleep

Among the more than 11,000 dearly departed inhabitants of Southeast Portland's Multnomah Park Cemetery, friends Eric Cordingley and David Anderson have their favorites: a reputed French madam, a young Norwegian institutionalized for being gay, and Louis Napoleon Lepley -- or, as they call him, "Louis the cannibal." Intriguing as their individual stories may be, together they help tell a bigger, darker tale

10 Aug 2012

$Thoracolumbar vertebrae fracture may be ‘silent’$

Thoracolumbar vertebrae fracture may be ‘silent’

Imaging is essential to avoid missing fractures to the thoracolumbar vertebrae in patients who have sustained blunt injury, UK researchers say.

10 Aug 2012

Patient, not surgeon factors influence patient-centric outcomes after knee surgery

Patient factors are more important than anything surgeons can control during total knee replacement surgery in the prediction of patient-reported outcome measures, report UK researchers.

9 Aug 2012

Researchers develop and test new prostate cancer screening method

9 Aug 2012

Amgen announces decision to stop ganitumab Phase 3 trial in advanced pancreatic cancer

Amgen today announced a decision to stop the ganitumab (AMG 479) Phase 3 GAMMA (Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas) trial following the recommendation of an independent Data Monitoring Committee (DMC) overseeing the trial.

9 Aug 2012

Advanced Radiology to offer Amyvid for detection of AD

Advanced Radiology, a division of RadNet, Inc., a national market leader providing high-quality, cost-effective diagnostic imaging services through a network of 237 fully-owned and operated outpatient imaging centers, announced it will be one of a small number of imaging centers in the U.S. to offer Amyvid, a radioactive tracer used in positron emission tomography – computed tomography (PET/CT) imaging that helps to detect the quantity of beta-amyloid plaque in patient's brains.

8 Aug 2012

Calcium and vitamin D supplements do not prevent bone loss in men with prostate cancer

Prescribing calcium and vitamin D supplements for men at risk of bone loss from hormonal treatment for prostate cancer seems like good medicine.

8 Aug 2012

Researchers help quell parents' worry about why infants seem to get sick so often

Researchers at the University of Michigan Health System are helping to quell parents' worry about why infants seem to get sick so often.

8 Aug 2012

New research hopes to uncover mystery behind breast cancer metastasis

If detected early, most cases of breast cancer are curable. But if the tumour has metastasized - or spread to a site outside of the breast - cure rates decline. A team of researchers from Lawson Health Research Institute and Western University have received $449,733 from the Canadian Breast Cancer Foundation - Ontario Region to study a rare subpopulation of tumour cells called cancer stem cells (CSCs) in hopes of uncovering the mystery behind metastasis.

8 Aug 2012

Researchers discover genetic cause of type VII mucopolysaccharidosis in Brazilian Terriers

The genetics research group led by Professor Hannes Lohi, based at the University of Helsinki and the Folkh-lsan Research Center, has, in collaboration with Adjunct Professor Kirsi Sainio's research group, discovered the cause of a life-threatening skeletal disorder affecting Brazilian Terriers. The disease is caused by a mutation in the GUSB gene.

7 Aug 2012

IOF, PAOS invite medical professionals to attend CME-accredited meeting in Jordan

The International Osteoporosis Foundation (IOF) and the Pan Arab Osteoporosis Society (PAOS) invite medical professionals to attend their joint meeting at the King Hussein Bin Talal Convention Centre, Dead Sea, Jordan, from September 27 to October 1, 2012.

6 Aug 2012

Bone News and Research

Physical activity effective in reducing sclerostin in premenopausal women

Therapeutic breaks for prostate cancer patients

PPMC earns Gold Seal of Approval for hip and knee joint replacement services

Proteonomix receives FDA approval to commence UMK-121 Phase 1 trial in end-stage liver disease

Longer, conical miniscrews most successful for orthodontic anchorage

Endocrine Society revises clinical practice guideline for management of thyroid dysfunction

Combination of novel drug therapy and PSA test can effectively detect prostate cancer

Promising stem cell therapy may prevent osteoarthritis after joint injury

FDA approved drug to treat Ph- acute lymphoblastic leukemia

Longer looks: Waking up to the need for sleep

Thoracolumbar vertebrae fracture may be ‘silent’

Patient, not surgeon factors influence patient-centric outcomes after knee surgery

Researchers develop and test new prostate cancer screening method

Amgen announces decision to stop ganitumab Phase 3 trial in advanced pancreatic cancer

Advanced Radiology to offer Amyvid for detection of AD

Calcium and vitamin D supplements do not prevent bone loss in men with prostate cancer

Researchers help quell parents' worry about why infants seem to get sick so often

New research hopes to uncover mystery behind breast cancer metastasis

Researchers discover genetic cause of type VII mucopolysaccharidosis in Brazilian Terriers

IOF, PAOS invite medical professionals to attend CME-accredited meeting in Jordan

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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