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New research center to expedite study of gene transfer approach

In an alliance aimed at bringing a new, personalized immunotherapy approach to patients with a wide variety of cancers, the University of Pennsylvania and Novartis announced today an exclusive global research and licensing agreement to further study and commercialize novel cellular immunotherapies using chimeric antigen receptor (CAR) technologies.

6 Aug 2012

Novartis, Penn partner to study and commercialize novel cellular immunotherapies for cancer

6 Aug 2012

Mechanism provides beneficial characteristics of energy-burning brown fat to white fat

Columbia University Medical Center (CUMC) researchers have identified a mechanism that can give energy-storing white fat some of the beneficial characteristics of energy-burning brown fat. The findings, based on studies of mice and of human fat tissue, could lead to new strategies for treating obesity and type 2 diabetes.

3 Aug 2012

Child abuse has repercussions for menarche

Researchers have found an association between childhood abuse and age at menarche onset, they report in the Journal of Adolescent Health.

3 Aug 2012

Alcohol decreases turnover of bone in post-menopausal women

Women after menopause tend to develop weaker bones from what is known as osteoporosis, which may lead to fractures (especially hip fractures) from falling. The weakness of the bones results from an imbalance between the normal resorption (a type of dissolving of old bone) and the laying down of new bone, an ongoing process for both men and women referred to as "bone turnover."

3 Aug 2012

Researchers identify how telomerase is recruited to chromosome ends

Stem cells are special. Nestled in muscle and skin, organ and bone, they bide their time over years or decades until called to replace damaged or lost tissue. One secret to their longevity is an enzyme called telomerase, which stills the relentless ticking of the molecular clock that limits the life span of other cells.

3 Aug 2012

Researchers discover surprising and unexpected plasticity in the embryonic endothelium

UCLA stem cell researchers have found for the first time a surprising and unexpected plasticity in the embryonic endothelium, the place where blood stem cells are made in early development.

3 Aug 2012

Researchers uncover 9 new genes associated with bone health

Researchers have uncovered 9 new genes associated with bone health. This collaborative study found clues to the cause of bone disorders such as osteoporosis, osteogenesis imperfecta, and high bone density syndromes by investigating the bone mineral content, strength and flexibility.

3 Aug 2012

Most incidences of shoulder joint instability are due to traumatic contact injuries

Summer is a peak season for many sports, and with that comes sport-related injuries. Among those injuries is shoulder joint dislocation. According to a literature review in the August 2012 issue of the Journal of the American Academy of Orthopaedic Surgeons, most incidences of shoulder joint instability are the result of traumatic contact injuries like force or falling on an outstretched arm; a direct blow to the shoulder area; forceful throwing, lifting or hitting; or contact with another player.

2 Aug 2012

Possible molecular link between circadian rhythm disturbances and increased inflammatory response

Scientists have known for some time that throwing off the body's circadian rhythm can negatively affect body chemistry. In fact, workers whose sleep-wake cycles are disrupted by night shifts are more susceptible to chronic inflammatory diseases such as diabetes, obesity and cancer.

2 Aug 2012

High maternal choline intake may reduce risk of hypertension and diabetes in babies

New research from Cornell University indicates that pregnant women who increase choline intake in the third trimester of pregnancy may reduce the risk of the baby developing metabolic and chronic stress-related diseases like high blood pressure and diabetes later in life.

2 Aug 2012

Exactech second quarter revenue increases 7% to $55.2 million

Exactech, Inc., a developer and producer of bone and joint restoration products for hip, knee, shoulder, spine and biologic materials, announced today revenue of $55.2 million for the second quarter of 2012, a 7% increase over $51.7 million in the second quarter of 2011.

31 Jul 2012

Obesity also affects sexual and urinary health in men

As a man's waistline grows, so can his experience with sexual dysfunction and frequent urination, say researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. The study, published in the August issue of the British Journal of Urology International (BJUI), is the first to comprehensively show that obesity in men affects not just their hearts and metabolism, but also their sexual and urinary health.

31 Jul 2012

Rye Radiology offers new 3D mammography that detects many breast cancers

Rye Radiology Associates, LLP, became the first facility between Manhattan and Syracuse to offer the new FDA-approved 3D mammography which finds more breast cancers than traditional mammography.

31 Jul 2012

Australia's top medical researchers for 2012 announced

Finalists for one of Australia’s longest running and most prestigious awards for medical research were announced today. This year’s winner will join a list of alumni winners that includes many of the country’s most respected scientists.

31 Jul 2012

Stem cell therapy holds promise for craniofacial bone repair

In the first human study of its kind, researchers found that using stem cells to re-grow craniofacial tissues-mainly bone-proved quicker, more effective and less invasive than traditional bone regeneration treatments.

31 Jul 2012

Burn wound MSCs potential source for skin grafting

Study findings suggest that burn wound eschar-derived mesenchymal cells represent a population of multipotent stem cells, which could be a new resource for engineering approaches to heal burn wounds.

30 Jul 2012

FDA grants Senesco's SNS01-T orphan-drug designation to treat lymphomas

Senesco Technologies, Inc. reported today that it was informed on July 26th that the U.S. Food and Drug Administration has granted orphan-drug designation for the company's lead drug candidate SNS01-T for treatment of both mantle cell lymphoma and diffuse large B-cell lymphoma.

30 Jul 2012

FDA accepts Exelixis’ cabozantinib NDA for filing

Exelixis, Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing the New Drug Application (NDA) for cabozantinib as a treatment for patients with progressive, unresectable, locally advanced, or metastatic medullary thyroid cancer (MTC).

30 Jul 2012

Patients with plantar fasciitis experience less pain and improved QOL after standard radiation therapy

Patients with plantar fasciitis (painful bone heel spur) experience significantly less pain and improved quality of life following a standard dose of external beam radiation therapy, a common cancer treatment similar to receiving an X-ray, according to a randomized, cooperative group study that was published online July 25, 2012, in the International Journal of Radiation, Oncology, Biology, Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO).

30 Jul 2012