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Shorter treatment with telaprevir-based combination regimen may benefit hepatitis C patients

Treatment with a telaprevir-based combination regimen for hepatitis C - heretofore a chronic, destructive and difficult to manage disease - effectively can be shortened to six months in about two-thirds of patients, finds a new study published Thursday in the New England Journal of Medicine.

16 Sep 2011

ITA president hosts International Small Bowel Transplant Symposium

Fifty-two year-old Paul McNeel, a fire chief from Leonardtown, Maryland was 37 in 1996 when a sudden health problem caused the loss of his small intestine. Almost all of it had to be surgically removed to save his life. For 13 years after that, McNeel continued to fight fires and stayed alive only because he fed himself a special liquid formula through a tube that went from a port in his chest directly to his heart and into his bloodstream.

15 Sep 2011

ODAC recommends ApoPharma's Ferriprox for FDA approval to treat transfusional iron overload

ApoPharma Inc. today announced that the Oncologic Drugs Advisory Committee (ODAC) to the U.S. Food and Drug Administration (FDA) voted 10 - 2 to recommend that the FDA grant accelerated approval of Ferriprox (deferiprone), an oral iron chelator, for the treatment of patients with transfusional iron overload when current chelation therapy is inadequate.

15 Sep 2011

Patients with hepatitis C may benefit from 24 week telaprevir-based regimen

University of Cincinnati research published in the Sept. 14, 2011, advance online edition of the New England Journal of Medicine shows that patients with hepatitis C who took a combination medication-a telaprevir-based regimen that is commonly used to treat the illness-for 24 weeks were cured.

15 Sep 2011

Major UK retailers, Liverpool scientists partner to reduce incidence of food poisoning

Scientists at the University of Liverpool are working with the major UK food retailers to reduce bacterial infections in chickens and reduce incidence of food poisoning in humans.

15 Sep 2011

First effective blood-stage vaccine against malaria

Scientists have identified the first effective blood-stage malaria vaccine, according to a New England Journal of Medicine study from University of Maryland School of Medicine researchers, in collaboration with the University of Bamako in Mali, West Africa, and other partners.

15 Sep 2011

Viamet commences VT-1161 Phase 1 clinical study to treat fungal infections

Viamet Pharmaceuticals, Inc., announced today that dosing has begun in a Phase 1 clinical study of VT-1161, an oral, potent and selective antifungal agent. VT-1161 is a novel small molecule discovered by Viamet Pharmaceuticals using its proprietary Metallophile Technology.

14 Sep 2011

'Achilles' heels' within HCV virus

Hopes for an effective vaccine and treatment against the potentially fatal hepatitis C virus (HCV) have received a major boost following the discovery of two 'Achilles' heels' within the virus.

14 Sep 2011

Pure maple syrup may promote a healthy liver

New research conducted at the University of Tokyo suggests that pure maple syrup may promote a healthy liver.

14 Sep 2011

Delcath announces updated Phase 2 trial results from metastatic neuroendocrine tumor cohort

Delcath Systems, Inc. announced that updated results from the metastatic neuroendocrine tumor (mNET) cohort of the Company's recently completed Phase 2 clinical trial were presented at the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) congress held this week in Munich, Germany.

13 Sep 2011

Cardiotrophin 1 has marked effect on fat and glucose metabolism

Scientists from the Center for Applied Medical Research (CIMA) of the University of Navarra (Spain) have discovered that cardiotrophin 1, a protein synthesized by muscle cells and adipose tissue, has a marked effect on fat and glucose metabolism.

13 Sep 2011

Breakthrough opens new avenues for hep C vaccine

Hopes for an effective vaccine and treatment against the potentially fatal hepatitis C virus (HCV) have received a major boost following the discovery of two ‘Achilles’ heels’ within the virus.

12 Sep 2011

Genentech submits vismodegib NDA to FDA for treatment of advanced basal cell carcinoma

Genentech, a member of the Roche Group, today announced that the company has submitted a New Drug Application for vismodegib to the U.S. Food and Drug Administration (FDA) for the treatment of people with advanced basal cell carcinoma (BCC) for whom surgery is considered inappropriate.

12 Sep 2011

ASTMH annual meeting to explore latest research on infectious diseases

The 60th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH) -- the largest of its kind in the world -- will bring together in one place global experts who are battling a wide range of bacteria, viruses, parasites and other pathogens that each year kill or sicken hundreds of millions of people.

12 Sep 2011

Specialists propose changes to allocation and distribution of organs for liver transplants

Transplantation specialists have proposed changes to the allocation and distribution of organs used for liver transplants. The recommended policy modifications take into account the scarcity of available organs, ensuring rapid allocation and delivery of the organ to those most in need in order to reduce mortality for waitlisted patients.

12 Sep 2011

UMSOM to receive FDA approval for whole parasite malaria vaccine clinical trials

For the first time, a malaria vaccine that uses the entire malaria parasite has proven safe and shown promise to produce a strong immune response in a clinical trial, according to a new study co-authored by researchers at the University of Maryland School of Medicine Center for Vaccine Development.

12 Sep 2011

Autophagy also mobilizes and exports cholesterol from cells

Researchers at the University of Ottawa Heart Institute (UOHI) have discovered that an ancient pathway called autophagy also mobilizes and exports cholesterol from cells.

9 Sep 2011

Landmark discovery in rapid spread of PRL-3 oncoprotein associated aggressive cancers

Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have made a landmark discovery in the battle against the rapid spread of aggressive cancers associated with PRL-3 oncoprotein.

9 Sep 2011

Longer looks: Unknowns in sports medicine; shackling pregnant prisoners

Medical experts say that multiple futile treatments is all too familiar and points to growing problems in sports medicine, a medical subspecialty that has been experiencing explosive growth. now researchers are questioning many of the procedures, including new ones that often have no rigorous studies to back them up. "Patients come in and say, 'I want the same thing that Tiger Woods had,' " said Dr. McDevitt, the sports medicine orthopedist in Maryland.

9 Sep 2011

UOHI team identifies that autophagy also mobilizes and exports cholesterol from cells

Researchers at the University of Ottawa Heart Institute (UOHI) have discovered that an ancient pathway called autophagy also mobilizes and exports cholesterol from cells.

9 Sep 2011

Liver News and Research

Shorter treatment with telaprevir-based combination regimen may benefit hepatitis C patients

ITA president hosts International Small Bowel Transplant Symposium

ODAC recommends ApoPharma's Ferriprox for FDA approval to treat transfusional iron overload

Patients with hepatitis C may benefit from 24 week telaprevir-based regimen

Major UK retailers, Liverpool scientists partner to reduce incidence of food poisoning

First effective blood-stage vaccine against malaria

Viamet commences VT-1161 Phase 1 clinical study to treat fungal infections

'Achilles' heels' within HCV virus

Pure maple syrup may promote a healthy liver

Delcath announces updated Phase 2 trial results from metastatic neuroendocrine tumor cohort

Cardiotrophin 1 has marked effect on fat and glucose metabolism

Breakthrough opens new avenues for hep C vaccine

Genentech submits vismodegib NDA to FDA for treatment of advanced basal cell carcinoma

ASTMH annual meeting to explore latest research on infectious diseases

Specialists propose changes to allocation and distribution of organs for liver transplants

UMSOM to receive FDA approval for whole parasite malaria vaccine clinical trials

Autophagy also mobilizes and exports cholesterol from cells

Landmark discovery in rapid spread of PRL-3 oncoprotein associated aggressive cancers

Longer looks: Unknowns in sports medicine; shackling pregnant prisoners

UOHI team identifies that autophagy also mobilizes and exports cholesterol from cells

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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