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Childhood physical and sexual abuse may increase risk of early or late onset menarche

Researchers from Boston University School of Medicine (BUSM) have found an association between childhood physical and sexual abuse and age at menarche.

28 Jul 2012

Genentech's BREVACTA study of ACTEMRA on rheumatoid arthritis meets primary endpoint

Genentech, a member of the Roche Group, today announced that the BREVACTA study of ACTEMRA (tocilizumab) given as a subcutaneous (SC) injection to patients with rheumatoid arthritis (RA) met its primary endpoint.

28 Jul 2012

New study sheds light on exactly how cigarette smoke causes osteoporosis

Almost 20 years after scientists first identified cigarette smoking as a risk factor for osteoporosis and bone fractures, a new study is shedding light on exactly how cigarette smoke weakens bones. The report, in ACS' Journal of Proteome Research, concludes that cigarette smoke makes people produce excessive amounts of two proteins that trigger a natural body process that breaks down bone.

28 Jul 2012

U of U researchers to develop new prosthetic device for veterans with limb amputations

Thousands of veterans and warfighters returning to the U.S. suffer with limb amputations, and for many, standard prosthetics are not an option. Skin issues or short remaining-limb length can cause amputees to forgo the typical socket-type attachment systems.

28 Jul 2012

Research presented at AIDS 2012 conference renews hope of cure for AIDS

Two studies presented at the XIX International AIDS Conference (AIDS 2012) and one published Wednesday in the British journal Nature "have given researchers renewed hope that a cure for AIDS may be possible," the Washington Post reports.

28 Jul 2012

ARIAD Pharmaceuticals commences ponatinib Phase 3 trial in newly diagnosed CML

ARIAD Pharmaceuticals, Inc. today announced the initiation of the randomized Phase 3 trial of ponatinib, its investigational pan-BCR-ABL inhibitor, in adult patients with newly diagnosed chronic myeloid leukemia (CML).

28 Jul 2012

AIDS roundup: Researchers examine whether the disease causes premature aging; Funding and treatment gaps; Bone marrow transplant treatments

News outlets report on scientific and political issues coming up at the International AIDS Conference being held in Washington.

27 Jul 2012

First Edition: July 27, 2012

Today's headlines include reports about a new effort launched by the Obama administration and insurers to fight health care fraud.

27 Jul 2012

Bone marrow transplant eradicates traces of HIV in men

Two men with longstanding HIV infections no longer have detectable HIV in their blood cells following bone marrow transplants. The virus was easily detected in blood lymphocytes of both men prior to their transplants but became undetectable by eight months post-transplant. The men, who were treated at Brigham and Women's Hospital (BWH), have remained on anti-retroviral therapy.

27 Jul 2012

Study highlights advantages of Baxano's iO-Flex system in performing lumbar spinal decompression

Baxano, Inc., the manufacturer of the innovative and cost-effective iO-Flex System, announced today the publication of a peer-reviewed study highlighting the advantages of the flagship iO-Flex technology in performing lumbar spinal decompression, a procedure that can be done with and without spinal fusion.

26 Jul 2012

FDA approves Horizon Pharma's RAYOS to treat key IL-6 mediated diseases

Horizon Pharma, Inc., announced today that the U.S. Food and Drug Administration (FDA) has approved RAYOS (prednisone) delayed-release tablets (1 mg, 2 mg and 5 mg) to treat a broad range of diseases including rheumatoid arthritis (RA), polymyalgia rheumatica (PMR), psoriatic arthritis (PsA), ankylosing spondylitis (AS), asthma and chronic obstructive pulmonary disease (COPD).

26 Jul 2012

American Society of Hematology announces new grant program for biomedical research

The American Society of Hematology (ASH), the world's largest professional organization dedicated to the causes and treatment of blood disorders, today announced its commitment of $9 million over a three-year period to provide funding, in the form of bridge grants, for its hematologists whose vital research will not be accomplished due to the severe funding reductions for biomedical research.

26 Jul 2012

Child who received first stem cell trachea transplant functioning well two years on

The first child stem cell-supported trachea transplant is functioning well two years on, according to an Article published Online First in The Lancet today. The follow-up of the procedure, carried out in 2010 at Great Ormond Street Hospital (GOSH), shows that the new organ has strengthened and does not appear to have induced any signs of rejection. The 13-year-old boy who received the transplant continues to breathe normally, has grown 11 cm in height and has returned to school. He does not require any anti-rejection therapy.

26 Jul 2012

Multi-center clinical trial results demonstrate safety and efficacy of carfilzomib for multiple myeloma

Researchers from John Theurer Cancer Center at HackensackUMC, one of the nation's 50 best hospitals for cancer, played leading roles in three separate multi-center studies with the new proteasome inhibitor carfilzomib published in Blood, a major peer-reviewed scientific journal.

26 Jul 2012

FDA grants priority review to GSK’s Promacta sNDA for treatment of thrombocytopenia

Ligand Pharmaceuticals Incorporated today announced that its partner GlaxoSmithKline has been granted priority review from the US Food and Drug Administration for the supplemental new drug application for Promacta to treat thrombocytopenia in adult patients with chronic hepatitis C virus (HCV) infection.

26 Jul 2012

Biomet prices previously announced offering of $550M aggregate senior notes due 2020

Biomet, Inc. today announced that it has priced its previously announced offering of $550 million aggregate senior notes due 2020, which has been increased to $1.0 billion aggregate principal amount of senior notes due 2020, at an issue price of 6.500%.

26 Jul 2012

Studies look at surgical site infections and hyperglycemia

Two recent studies in the July issues of the Journal of Bone and Joint Surgery (JBJS) looked at surgical site infections and hyperglycemia, the technical term for high blood glucose, or high blood sugar.

26 Jul 2012

MRI useful for identifying bone lesions in diabetic feet

Identification of specific bone lesions in the feet of patients with diabetes can be achieved with magnetic resonance imaging, show study findings.

25 Jul 2012

bluebird bio completes $60 million Series D financing

bluebird bio, a leader in the development of innovative gene therapies for severe genetic disorders, today announced the successful completion of a $60 million Series D financing. In this round, new investors Deerfield Partners, RA Capital, Ramius Capital Group, and two undisclosed blue chip public investment funds joined existing investors ARCH Venture Partners, Third Rock Ventures, TVM Capital, and Forbion Capital Partners. In addition, Shire plc joined the round as a strategic investor.

25 Jul 2012

New cell regeneration method uses gene therapy to repair bone tissue

Researchers at the Royal College of Surgeons in Ireland (RCSI) have developed a new method of repairing bone using synthetic bone graft substitute material, which combined with gene therapy, can mimic real bone tissue and has potential to regenerate bone in patients who have lost large areas of bone from either disease or trauma.

25 Jul 2012

Bone News and Research

Childhood physical and sexual abuse may increase risk of early or late onset menarche

Genentech's BREVACTA study of ACTEMRA on rheumatoid arthritis meets primary endpoint

New study sheds light on exactly how cigarette smoke causes osteoporosis

U of U researchers to develop new prosthetic device for veterans with limb amputations

Research presented at AIDS 2012 conference renews hope of cure for AIDS

ARIAD Pharmaceuticals commences ponatinib Phase 3 trial in newly diagnosed CML

AIDS roundup: Researchers examine whether the disease causes premature aging; Funding and treatment gaps; Bone marrow transplant treatments

First Edition: July 27, 2012

Bone marrow transplant eradicates traces of HIV in men

Study highlights advantages of Baxano's iO-Flex system in performing lumbar spinal decompression

FDA approves Horizon Pharma's RAYOS to treat key IL-6 mediated diseases

American Society of Hematology announces new grant program for biomedical research

Child who received first stem cell trachea transplant functioning well two years on

Multi-center clinical trial results demonstrate safety and efficacy of carfilzomib for multiple myeloma

FDA grants priority review to GSK’s Promacta sNDA for treatment of thrombocytopenia

Biomet prices previously announced offering of $550M aggregate senior notes due 2020

Studies look at surgical site infections and hyperglycemia

MRI useful for identifying bone lesions in diabetic feet

bluebird bio completes $60 million Series D financing

New cell regeneration method uses gene therapy to repair bone tissue

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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