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$Researchers reveal gene variants that delay fracture healing$

Researchers reveal gene variants that delay fracture healing

Slow-healing or non-healing bone fractures in otherwise healthy people may be caused by gene variants that are common in the population, according to Penn State College of Medicine researchers.

15 Oct 2014

Inflammation in tissue creates a niche for cancer cells

In order to invade healthy tissue, tumor cells must leave the actual tumor and enter the bloodstream or lymphatic system. For this purpose, they use certain enzymes, proteases that break down the tissue surrounding the tumor, thus opening the way for tumor cells to reach blood or lymphatic vessels. To keep the proteases in check, the body produces inhibitors such as the protein TIMP-1, which thwart the proteases in their work.

15 Oct 2014

Tannic acid may help ease impact of bacterial lung infections in CF patients

By screening over 2,000 approved drugs and natural products, scientists have shown that tannic acid may help ease the impact of bacterial lung infections in cystic fibrosis patients.

14 Oct 2014

Women prescribed different medication than men to bring down blood pressure

Women who are treated for high blood pressure are not given the same medication as men, nor do they hit the treatment targets as often, reveals a thesis from the University of Gothenburg.

14 Oct 2014

Researchers develop DNA-based drug delivery system that targets cancer cells

Biomedical engineering researchers have developed a drug delivery system consisting of nanoscale "cocoons" made of DNA that target cancer cells and trick the cells into absorbing the cocoon before unleashing anticancer drugs. The work was done by researchers at North Carolina State University and the University of North Carolina at Chapel Hill.

14 Oct 2014

Cornell University researchers reveal details of how MERS-CoV enters host cells

Cornell University researchers have uncovered details of how the deadly Middle East respiratory syndrome coronavirus (MERS-CoV) enters host cells, and offer possible new avenues for treatment.

14 Oct 2014

New culture system confirms amyloid theory, can revolutionize drug discovery for Alzheimer's disease

An innovative laboratory culture system has succeeded, for the first time, in reproducing the full course of events underlying the development of Alzheimer's disease.

13 Oct 2014

Medical geneticists diagnose genetic syndromes, improve children’s quality of life

The genes children inherit determine everything from their height to their hair color. But sometimes, a child's genetic code also contains hidden abnormalities that can cause an array of health issues, such as developmental delays or physical or mental illness.

13 Oct 2014

Rockefeller University researchers gain new insight into how cholesterol processes in our body

In spite of its dangerous reputation, cholesterol is in fact an essential component of human cells. Manufactured by the cells themselves, it serves to stiffen the cell's membrane, helping to shape the cell and protect it. By mapping the structure of a key enzyme involved in cholesterol production, Rockefeller University researchers and a colleague in Italy have gained new insight into this complex molecular process.

12 Oct 2014

New UCLA study reveals why people with autism experience neural stem cell overgrowth after birth

People with autism spectrum disorder often experience a period of accelerated brain growth after birth. No one knows why, or whether the change is linked to any specific behavioral changes.

10 Oct 2014

Slug flow microextraction method for drug testing yields results in one minute

A new technique makes it possible to quickly detect the presence of drugs or to monitor certain medical conditions using only a single drop of blood or urine, representing a potential tool for clinicians and law enforcement.

10 Oct 2014

Decaffeinated coffee may benefit liver health

Researchers from the National Cancer Institute report that decaffeinated coffee drinking may benefit liver health. Results of the study published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show that higher coffee consumption, regardless of caffeine content, was linked to lower levels of abnormal liver enzymes. This suggests that chemical compounds in coffee other than caffeine may help protect the liver.

10 Oct 2014

Researchers are developing compounds to combat causative agents of periodontitis

A total 12 million Germans suffer from periodontitis. If the inflammation remains untreated, this could lead to tooth loss. However, it is also suspected of triggering many other diseases, like cardiopulmonary diseases. Researchers are studying the interactions, and developing compounds to combat the causative agents.

9 Oct 2014

Molecular biologists awarded NIH grant to identify new compounds to fight malaria parasite

A team of molecular biologists, jointly led by Clemson University professor Jim Morris, was awarded a $151,121 grant from the National Institutes of Health to identify new compounds with anti-malarial activity for a deadly parasite species that kills hundreds of thousands of people each year.

9 Oct 2014

AT2101 drug, evaluated for Gaucher disease, slows progression of Parkinson's disease in mice

A new study from UCLA found that a drug being evaluated to treat an entirely different disorder helped slow the progression of Parkinson's disease in mice.

9 Oct 2014

Contaminated duodenoscopes associated with E coli outbreak at Illinois hospital

Despite no lapses in the disinfection process recommended by the manufacturer being identified, specialized gastrointestinal endoscopes called duodenoscopes had bacterial contamination associated with an outbreak of a highly resistant strain of E coli at a hospital in Illinois, according to a study in the October 8 JAMA, a theme issue on infectious disease.

8 Oct 2014

Magnesium essential to the activity of vitamin D

Extensive research has shown that vitamin D deficiencies play a major role in the development of dozens of diseases, including breast, prostate and colon cancer, as well as diabetes, heart disease, arthritis, osteoporosis, psoriasis and mental illness.

8 Oct 2014

Researchers use computer based predictions to combat AIDS

The battle against AIDS cannot be won in the laboratory alone. To fight the potentially deadly virus that 34 million people are suffering from we need help from computers.

8 Oct 2014

LLNL scientists issued patent for producing antimicrobial compounds to fight superbugs

Superbugs, antibiotic-resistant bacteria, have been on the rise since antibiotics were first introduced 80 years ago. That's because these germ-fighting agents have lost their punch from being overprescribed and misused, allowing bacteria pathogens to develop immunities against them.

8 Oct 2014

New drug discovery tool against Ebola virus

University of Utah biochemists have reported a new drug discovery tool against the Ebola virus. According to a study published in this week's online edition of Protein Science, they have produced a molecule, known as a peptide mimic, that displays a functionally critical region of the virus that is universally conserved in all known species of Ebola.

8 Oct 2014

Enzyme News and Research

Researchers reveal gene variants that delay fracture healing

Inflammation in tissue creates a niche for cancer cells

Tannic acid may help ease impact of bacterial lung infections in CF patients

Women prescribed different medication than men to bring down blood pressure

Researchers develop DNA-based drug delivery system that targets cancer cells

Cornell University researchers reveal details of how MERS-CoV enters host cells

New culture system confirms amyloid theory, can revolutionize drug discovery for Alzheimer's disease

Medical geneticists diagnose genetic syndromes, improve children’s quality of life

Rockefeller University researchers gain new insight into how cholesterol processes in our body

New UCLA study reveals why people with autism experience neural stem cell overgrowth after birth

Slug flow microextraction method for drug testing yields results in one minute

Decaffeinated coffee may benefit liver health

Researchers are developing compounds to combat causative agents of periodontitis

Molecular biologists awarded NIH grant to identify new compounds to fight malaria parasite

AT2101 drug, evaluated for Gaucher disease, slows progression of Parkinson's disease in mice

Contaminated duodenoscopes associated with E coli outbreak at Illinois hospital

Magnesium essential to the activity of vitamin D

Researchers use computer based predictions to combat AIDS

LLNL scientists issued patent for producing antimicrobial compounds to fight superbugs

New drug discovery tool against Ebola virus

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