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Three vaccine candidates provide complete protection against Zika virus in rhesus monkeys

A month after announcing that two promising vaccine candidates provided mice with complete protection against the Zika virus, a research team at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research and the University of São Paulo, now reports achieving complete protection against Zika virus in rhesus monkeys.

5 Aug 2016

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%.

4 Aug 2016

Proper technique, training can prevent shoulder injuries in elite and competitive swimmers

Elite and competitive swimmers log between 60,000 and 80,000 meters weekly--swimming the length of an Olympic-sized pool 1,200 times--which places significant stress on their shoulder joints.

4 Aug 2016

Mount Sinai neurosurgeon first to use CaptiView image injection system during microscopic surgery

Joshua Bederson, MD, Professor and System Chair for the Department of Neurosurgery at Mount Sinai Health System, is the first neurosurgeon to use CaptiView - a microscope image injection system from Leica Microsystems that overlays critical virtual reality imaging directly onto the brain when viewed through the eyepiece, known as the ocular, during surgery.

4 Aug 2016

Research could help develop better therapies for new subtype of adenocarcinoma patients

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease.

4 Aug 2016

Clinical trials in children commonly go uncompleted or unpublished, study finds

Recent legislation is encouraging clinical trials in children, including the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act.

4 Aug 2016

Study shows hospitals that send more number of heart patients to ICU perform worse in quality of care

Patients who suffer heart attacks, or flare-ups of congestive heart failure, can be cared for in a variety of hospital locations. But a new study suggests that they'll fare worse in hospitals that rely heavily on their intensive care units to care for patients like them.

3 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Reprogramming of the molecular pathways underlying normal metabolism is essential for T cell infection-fighting function and for the immune system to form a "memory" of the microbes it has already encountered. But exactly how metabolism in exhausted T cells is maintained in chronic infections and cancer is a missing element in this line of research.

3 Aug 2016

Hyperkyphosis may be passed on from parents to children

Researchers from the Harvard affiliated Hebrew SeniorLife Institute for Aging Research recently published a study in the Journal of Bone and Mineral Research, suggesting that hyperkyphosis may be heritable, or passed on from parents to offspring.

3 Aug 2016

Penn's ADCC receives $8.8 million grant to continue research on treatment for AD and related dementias

The University of Pennsylvania's Alzheimer's Disease Core Center has been awarded an estimated $8.8 million over five years from the National Institute on Aging to continue its mission of investigating mechanisms, diagnostics, treatments and strategies for Alzheimer's Disease (AD) and related dementias including Parkinson's disease (PD), Parkinson's disease dementia (PDD), Lewy Body dementia (LBD) and frontotemporal lobar degeneration (FTLD).

3 Aug 2016

Lower weight late in life linked to greater risk for Alzheimer's disease

Researchers at Brigham and Women's Hospital and Massachusetts General Hospital have found an association between lower weight and more extensive deposits of the Alzheimer's-associated protein beta-amyloid in the brains of cognitively normal older individuals.

2 Aug 2016

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

In an attempt to correct defects in the energy generation that contribute to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure.

2 Aug 2016

GW researchers identify new way to regulate chronic toxoplasmosis

New research critical to treatment for chronic toxoplasmosis, one of the most common parasitic diseases worldwide, was published in the Journal of Experimental Medicine.

2 Aug 2016

School-based program helps parents and children from low-income families eat healthier food

Brighter Bites, a school-based program that combines the distribution of donated produce with nutritional education and a fun food experience for low-income families in food desert areas, was successful in improving the intake of fruits and vegetables in first-grade children and their parents, according to a new study by The University of Texas Health Science Center at Houston.

2 Aug 2016

AOFAS volunteers travel to Vietnam for treating people with lower extremity deformities

Volunteers from the American Orthopaedic Foot & Ankle Society returned to Vietnam this year to provide corrective surgery for children and adults with lower extremity deformities and disabilities.

30 Jul 2016

Brief smartphone exercises can help uplift mood

Brief, directed smartphone exercises can help quickly improve our mood. This is the latest finding from psychologists at the University of Basel and their international colleagues, reported in the journal Frontiers in Psychology.

29 Jul 2016

Study clarifies role of KLF12 in CRC tumor growth

Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses.

29 Jul 2016

Breast cancer patients who use social media express more satisfaction about treatment decisions

Women who engaged on social media after a breast cancer diagnosis expressed more deliberation about their treatment decision and more satisfaction with the path they chose, a new study from the University of Michigan Comprehensive Cancer Center finds.

29 Jul 2016

Study verifies human gene therapy in MPS I animal model

Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I. It is caused by a deficiency of the key enzyme IDUA needed to break down complex sugars in cells.

29 Jul 2016

Medical School News and Research

Three vaccine candidates provide complete protection against Zika virus in rhesus monkeys

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

Proper technique, training can prevent shoulder injuries in elite and competitive swimmers

Mount Sinai neurosurgeon first to use CaptiView image injection system during microscopic surgery

Research could help develop better therapies for new subtype of adenocarcinoma patients

Clinical trials in children commonly go uncompleted or unpublished, study finds

Study shows hospitals that send more number of heart patients to ICU perform worse in quality of care

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Hyperkyphosis may be passed on from parents to children

Penn's ADCC receives $8.8 million grant to continue research on treatment for AD and related dementias

Lower weight late in life linked to greater risk for Alzheimer's disease

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

GW researchers identify new way to regulate chronic toxoplasmosis

School-based program helps parents and children from low-income families eat healthier food

AOFAS volunteers travel to Vietnam for treating people with lower extremity deformities

Brief smartphone exercises can help uplift mood

Study clarifies role of KLF12 in CRC tumor growth

Breast cancer patients who use social media express more satisfaction about treatment decisions

Study verifies human gene therapy in MPS I animal model

Industry Focus eBook - Cell biology (5th edition) eBook

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A New Approach to Preventing Bladder Cancer Recurrence

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