Therapy News and Research

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The effectiveness of three repurposed drugs in preventing serious SARS-CoV-2 infection in non-hospitalized adults

Researchers conducted a phase III clinical trial to test the effectiveness of three repurposed drugs - metformin, ivermectin, and fluvoxamine, in preventing progression to severe COVID-19.

22 Aug 2022

Sanders-Brown director receives $1.5 million grant to advance research on Alzheimer's treatment

Linda J. Van Eldik, Ph.D., director of the University of Kentucky Sanders-Brown Center on Aging, is part of a $1.5 million grant to help further research into a possible treatment for Alzheimer's disease.

19 Aug 2022

Scientists identify new driver for rare type of liver cancer

Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver.

19 Aug 2022

New clinical trial may establish a standard of care for patients with oligometastatic kidney cancer

Kidney cancer encompasses a wide spectrum and can present with extensive metastases or just a handful. However, today all patients are treated the same. They all receive medication.

19 Aug 2022

Study reveals a strong potential therapy for treatment-resistant depression

Deep brain stimulation (DBS) to the superolateral branch of the medial forebrain bundle (MFB), which is linked to reward and motivation, revealed metabolic brain changes over 12 months post-DBS implantation, making it a strong potential therapy for treatment-resistant depression according to researchers at UTHealth Houston.

19 Aug 2022

Researchers receive grant to develop purification membranes for large-scale manufacturing of viral vectors

With a $6 million grant from the National Science Foundation, researchers at the University of Arkansas and two partner institutions will develop purification membranes for future large-scale manufacturing of viral vectors and virus-like particles.

19 Aug 2022

SARS-CoV-2 mRNA vaccination reveals HIV hiding in immune cells

Vaccination with a SARS-CoV-2 mRNA vaccine revealed HIV hiding in immune cells in blood from people with HIV, according to lab research led by Weill Cornell Medicine investigators.

19 Aug 2022

UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

UC San Diego Health is first in the nation to offer a new injectable medication to patients with nerve damage caused by hereditary transthyretin amyloidosis, a rare disease that can be fatal without management.

18 Aug 2022

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

A recent article illustrated the derivation and validation of the QCOVID4 risk determination algorithm for predicting COVID-19 hospitalization and death risk in England.

18 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

Metabolic Mind Award Program recognizes champions in the emerging field of metabolic psychiatry

The Baszucki Brain Research Fund and the Milken Institute's Center for Strategic Philanthropy today announced the launch of the Metabolic Mind Award Program, recognizing champions working at the intersection of metabolism and mental health in the emerging field of metabolic psychiatry. This year's award focus will be on Ketogenic Metabolic Therapy for mental health.

18 Aug 2022

Study detects asymptomatic monkeypox virus infection

A new study published in the Annals of Internal Medicine aimed to assess the presence of MPVX in the anorectal samples of MSM who had undergone routine tests for sexually transmitted infections from 5th June to 11th July 2022.

17 Aug 2022

UH professor seeks to tackle the homelessness epidemic, repair a fragmented aid industry

While volunteering at an Indian orphanage in 1984, Dr. David Buck found his passion for helping those most in need during an encounter with the greatest humanitarian in human history – Mother Teresa.

17 Aug 2022

Machine learning models can predict posttreatment recurrence in patients with early-stage hepatocellular carcinoma

According to ARRS' American Journal of Roentgenology (AJR), machine learning models applied to presently underutilized imaging features could help construct more reliable criteria for organ allocation and liver transplant eligibility.

17 Aug 2022

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways that lead to drug resistance while increasing cancer-fighting ability and reducing side effects.

17 Aug 2022

Acid ceramidase is a SARS-CoV-2 host factor, study says

Fluoxetine, a common antidepressant, inhibits the SARS-CoV-2 coronavirus in cell cultures and in preparations from human lung tissue. This was demonstrated by researchers at Julius-Maximilians-Universität (JMU) Würzburg in the summer of 2020. However, the mechanism of this inhibition was utterly unclear, so the teams continued their research.

17 Aug 2022

Study finds a declining trend in use of medications for sleep disturbance among Americans

Americans aren't turning to pharmaceutical options as often in the never-ending battle for a good night's sleep.

16 Aug 2022

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.

16 Aug 2022

Antiviral drugs in combination with antibody therapies could help protect people from the flu pandemic

Researchers at McMaster University have found a class of well-known antiviral drugs could be part of a one-two punch to treat seasonal influenza and prevent a flu pandemic when used in combination with antibody therapies.

16 Aug 2022

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

As a result of this partnership, Inventia Life Science will now offer BioLamina’s extensive range of Biolaminin® products incorporated into the pre-validated library of RASTRUM™ Matrices, recapitulating the key motifs found in the native tissue of various cell types.

From Inventia Life Science 16 Aug 2022

Therapy News and Research

The effectiveness of three repurposed drugs in preventing serious SARS-CoV-2 infection in non-hospitalized adults

Sanders-Brown director receives $1.5 million grant to advance research on Alzheimer's treatment

Scientists identify new driver for rare type of liver cancer

New clinical trial may establish a standard of care for patients with oligometastatic kidney cancer

Study reveals a strong potential therapy for treatment-resistant depression

Researchers receive grant to develop purification membranes for large-scale manufacturing of viral vectors

SARS-CoV-2 mRNA vaccination reveals HIV hiding in immune cells

UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

New strategies to enhance the survival of children with neuroblastoma

Metabolic Mind Award Program recognizes champions in the emerging field of metabolic psychiatry

Study detects asymptomatic monkeypox virus infection

UH professor seeks to tackle the homelessness epidemic, repair a fragmented aid industry

Machine learning models can predict posttreatment recurrence in patients with early-stage hepatocellular carcinoma

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

Acid ceramidase is a SARS-CoV-2 host factor, study says

Study finds a declining trend in use of medications for sleep disturbance among Americans

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Antiviral drugs in combination with antibody therapies could help protect people from the flu pandemic

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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