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Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years - and 25% of patients whose tumor cells had a specific protein lived at least that long.

3 Jun 2019

A new approach to predict complications after surgery for patients with larynx cancer

A technique that illuminates blood flow during surgery predicted which head and neck cancer patients were likely to have issues with wound healing. It could enable surgeons to make adjustments during surgery or recovery to improve outcomes.

31 May 2019

New targeted therapy using radio waves blocks growth of liver cancer cells, study shows

A new targeted therapy using non-thermal radio waves has been shown to block the growth of liver cancer cells anywhere in the body without damaging healthy cells, according to a study conducted by scientists at Wake Forest School of Medicine, part of Wake Forest Baptist Health.

31 May 2019

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

For patients with operable non-small cell lung cancer, pre-surgical "neoadjuvant" treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and nine other research centers

31 May 2019

Tumor-fighting combination targets aggressive form of brain cancer

Researchers have paired a specialized diet and a tumor-fighting drug and found the non-toxic combination helps to destroy the two major cells found in an aggressive form of brain cancer, the team reports in the online edition of the Nature group journal Communications Biology.

31 May 2019

Study highlights the need to educate oncologists about molecular profiling

A questionnaire aimed at assessing how well community oncologists understand "molecular profiling" results from tumor specimens found that 69 percent of participants either said they don't know the answers, or they responded incorrectly.

31 May 2019

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

A team of researchers from Indiana University and Memorial Sloan Kettering Cancer Center have been awarded a $4.1 million National Cancer Institute "Cancer Moonshot" grant to develop immunotherapy treatments for cancer in children and adolescents, especially those with leukemia.

31 May 2019

Research reveals immunomodulatory role of ent-kaurane diterpenoids toward NK cells

As early responders in the surveillance of malignant cells, natural killer cells play a significant role in the control of transformed cells at the tumor initiation stage through direct cytolysis. For this reason, NK cell-based immunotherapy is a potential therapeutic strategy for tumor sufferers.

31 May 2019

Researchers unveil clues into how breast cancer cells spread around the body

Researchers have unveiled clues into how breast cancer cells spread around the body.

31 May 2019

Cancer researchers discover new functions for common oncogene MYC

Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US every year.

30 May 2019

Study identifies patterns of chronic lymphocytic leukemia growth

In patients with chronic lymphocytic leukemia, the rate of disease growth is apt to follow one of three trajectories: relentlessly upward, steadily level, or something in between, scientists at Dana-Farber Cancer Institute, the Broad Institute of MIT and Harvard, Massachusetts General Hospital, and the University of Washington report in a new study.

29 May 2019

Researchers describe how prostate cancer cells develop ability to mimic osteoblasts

Prostate cancer often becomes lethal as it spreads to the bones, and the process behind this deadly feature could potentially be turned against it as a target for bone-targeting radiation and potential new therapies.

29 May 2019

Computer-assisted diagnostic method aids in early detection of brain tumor growth

A computer-assisted diagnostic procedure helps physicians detect the growth of low-grade brain tumors earlier and at smaller volumes than visual comparison alone, according to a study published May 28 in the open-access journal PLOS Medicine by Hassan Fathallah-Shaykh of the University of Alabama at Birmingham, and colleagues.

From PLOS ONE 29 May 2019

Researchers discover signaling protein that may protect parathyroid glands from hyperactivity

Overactive parathyroid glands,which control the body's blood calcium levels, can lead to kidney stones, neuropsychiatric disorders and bone abnormalities, particularly among elderly women.

29 May 2019

Surgery can be beneficial for one type of primary central nervous system lymphoma

Through a systematic review of published studies going back 50 years, Johns Hopkins Medicine researchers say they have identified a distinct subtype of primary central nervous system lymphoma that should be considered for surgical removal, suggesting a major shift in how this type of tumor is evaluated and managed.

From Johns Hopkins Medicine 29 May 2019

New laboratory test has potential to accurately predict spread of breast cancer

Researchers at The Johns Hopkins University and other institutions report that a new laboratory test that induces cancer cells to squeeze through narrow spaces has the potential to accurately predict which breast cancers and other solid tumors are likely to spread, or metastasize, to other sites.

From Johns Hopkins Medicine 29 May 2019

Study uncovers new oncogenic function of receptor associated with Alzheimer's disease

Common and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease.

28 May 2019

Researchers discover unexpected survival mechanism of a subset of cancer cells

Embedded at the end of chromosomes are structures called "telomeres" that in normal cells become shorter as cells divide. As the shortening progresses it triggers cell proliferation arrest or death. Cancer cells adopt different strategies to overcome this control mechanism that keeps track of the number of times that a cell has divided.

28 May 2019

A final comfort: ‘Palliative transport’ brings dying children home

Anne Brescia sat beside her only child, Anthony, as he lay unconscious in a hospital bed at age 16. Just a few months before, he was competing in a swim meet; now cancer was destroying his brain. Brescia couldn’t save her son. But she was determined to bring him home.

28 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Tumor News and Research

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

A new approach to predict complications after surgery for patients with larynx cancer

New targeted therapy using radio waves blocks growth of liver cancer cells, study shows

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

Tumor-fighting combination targets aggressive form of brain cancer

Study highlights the need to educate oncologists about molecular profiling

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

Research reveals immunomodulatory role of ent-kaurane diterpenoids toward NK cells

Researchers unveil clues into how breast cancer cells spread around the body

Cancer researchers discover new functions for common oncogene MYC

Study identifies patterns of chronic lymphocytic leukemia growth

Researchers describe how prostate cancer cells develop ability to mimic osteoblasts

Computer-assisted diagnostic method aids in early detection of brain tumor growth

Researchers discover signaling protein that may protect parathyroid glands from hyperactivity

Surgery can be beneficial for one type of primary central nervous system lymphoma

New laboratory test has potential to accurately predict spread of breast cancer

Study uncovers new oncogenic function of receptor associated with Alzheimer's disease

Researchers discover unexpected survival mechanism of a subset of cancer cells

A final comfort: ‘Palliative transport’ brings dying children home

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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