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TGen, Geisinger Health System sign strategic research agreement

The Translational Genomics Research Institute (TGen) and Geisinger Health System today announced the signing of a strategic research agreement that provides for a focused look at the gaps in clinical medicine where biomedical research can make a difference.

4 Feb 2010

Validation results of SmartChip Real-Time PCR System to be presented at CHI's conference

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, today announced that WaferGen scientists will present validation results of the company's SmartChip™ Real-Time PCR System at Cambridge Healthcare Institute's 17th International Molecular Medicine Tri-Conference.

3 Feb 2010

Researchers discover anomalies that cause lack of motivation in ADHD children

Until now, attention-deficit/hyperactivity disorder (ADHD) was related to alterations in the brain affecting attention and cognitive processes. Researchers at Universitat Aut-noma de Barcelona and the Vall d'Hebron University Hospital for the first time have discovered anomalies in the brain's reward system related to the neural circuits of motivation and gratification.

3 Feb 2010

Major study of perfusion imaging under way to assess value of alternative diagnostic methods

Cardiologists and heart imaging specialists at 15 medical centers in eight countries, and led by researchers at Johns Hopkins, have enrolled the first dozen patients in a year-long investigation to learn whether the subtle squeezing of blood flow through the inner layers of the heart is better than traditional SPECT nuclear imaging tests and other diagnostic radiology procedures for accurately tracking the earliest signs of coronary artery clogs.

3 Feb 2010

Study shows Cymbalta reduces chronic low back pain

In a new study, 60 mg of Cymbalta® (duloxetine HCl) taken once daily significantly reduced chronic low back pain, as measured by the Brief Pain Inventory (BPI) average pain rating, compared with placebo.

3 Feb 2010

FDA approves Labopharm's OLEPTRO antidepressant for MDD

Labopharm Inc. today announced the U.S. Food and Drug Administration (FDA) has approved OLEPTRO(TM) (trazodone hydrochloride) Extended Release Tablets, a novel once-daily formulation of the antidepressant trazodone, for the treatment of major depressive disorder (MDD) in adults. OLEPTRO(TM) utilizes CONTRAMID(R), Labopharm's clinically validated technology that controls the release of active substances within oral medications.

3 Feb 2010

Daiichi Sankyo initiates Phase III trial of edoxaban in reducing recurrent VTE complications

Daiichi Sankyo Company, Limited, announced today that it has initiated a new large-scale pivotal Phase III trial for edoxaban, its investigational oral Factor Xa inhibitor. This new study, called HOKUSAI (pronounced hoe·koo·sigh) VTE, is evaluating the safety and efficacy of edoxaban in reducing recurrent venous thromboembolic (VTE) complications in patients with deep vein thrombosis (DVT) and/or pulmonary embolism (PE).

3 Feb 2010

New study compares two treatment options for clubfoot - Ponseti method and surgical treatment

Clubfoot affects one in a thousand babies born in the United States, but with proper corrective treatment and follow-up, infants born with clubfoot can have feet compatible with an active, normal lifestyle.

3 Feb 2010

Penn Medicine experts available to offer medical insight and commentary during 2010 Winter Olympics

Experts from the University of Pennsylvania School of Medicine are available to offer expert medical insight and commentary during the 2010 Winter Olympics in Vancouver on issues ranging from the effects of performance enhancing drugs to concerns about the spread of novel H1N1, head trauma and more.

3 Feb 2010

New study to investigate preventative programmes for anaemia control in young women

A new study led by LSTM will investigate whether long-term weekly iron and folic acid supplementation can reduce anaemia without increasing the risk of contracting malaria.

3 Feb 2010

Report: California biomedical industry faces unprecedented challenges

The biomedical industry is one of the most recession-resilient sectors in California's hard-hit economy and a critical driver of innovation, job growth and revenue that will help lead the state to economic recovery, according to a report released today by the California Healthcare Institute (CHI) and PricewaterhouseCoopers LLP (PwC).

3 Feb 2010

Gene variants protect sexually-abused victims from alcohol dependence, says study

Exposure to severe stress early in life increases the risk of alcohol and drug addiction. Yet surprisingly, some adults sexually abused as children - and therefore at high risk for alcohol problems - carry gene variants that protect them from heavy drinking and its effects, according to researchers at Washington University School of Medicine in St. Louis.

3 Feb 2010

Maximizing quality in clinical trials is emphasized at community workshop

A community workshop sponsored by SNM's Clinical Trials Network (CTN) officially kicked off on Feb. 1, in Albuquerque, N.M., and presented participants with a series of educational sessions on the use of molecular imaging in clinical trials for investigational therapeutic drugs.

3 Feb 2010

Certain cancer surgeries for low-risk patients may be performed at community hospitals

Low-risk patients who require certain cancer surgeries can have the procedures performed with low operative mortality rates at community hospitals, according to a new study.

3 Feb 2010

SNM Clinical Trials Network Workshop: Experts to discuss usage of molecular imaging

On Feb. 2, the final day of the second annual SNM Clinical Trials Network Workshop, experts working in various facets of the molecular imaging community met in Albuquerque, N.M., to discuss the nuts and bolts of using imaging in clinical trials and the challenges and opportunities ahead in the regulatory landscape.

3 Feb 2010

Insecticide-treated bed-nets can help in preventing malaria

Tanya Marchant of the London School of Hygiene and Tropical Medicine tells Peter Goodwin about her research findings on how to improve the prevention of malaria.

3 Feb 2010

Multiple ultrasounds may not be necessary for diagnosing DVT in some low-risk patients

An analysis of previous studies suggests that for patients with a suspected blood clot in a deep vein of a leg, withholding anticoagulation therapy after a negative whole-leg compression ultrasound is associated with a low risk of developing a blood clot during the subsequent 3 months, suggesting that multiple ultrasounds may not be necessary for some low-risk patients, according to an article in the February 3 issue of JAMA.

3 Feb 2010

New 3D scaffold for stem cell renewal

Medical researchers were shocked to discover that virtually all human embryonic stem cell lines being used in 2005 were contaminated. Animal byproducts used to line Petri dishes had left traces on the human cells. If those cells had been implanted in a human body they likely would have been rejected by the patient's immune system.

3 Feb 2010

Research opens new avenues for understanding genetic basis of type 2 diabetes

Together with colleagues in Barcelona, researchers at the University of North Carolina at Chapel Hill have generated a complete map of the areas of the genome that control which genes are "turned on" or "off."

3 Feb 2010

TGen, Horizon Discovery partner in development of novel cancer cell-lines

The Translational Genomics Research Institute (TGen) and Horizon Discovery today announced plans to develop human disease models for use in TGen's cancer research.

3 Feb 2010

Medicine News and Research

TGen, Geisinger Health System sign strategic research agreement

Validation results of SmartChip Real-Time PCR System to be presented at CHI's conference

Researchers discover anomalies that cause lack of motivation in ADHD children

Major study of perfusion imaging under way to assess value of alternative diagnostic methods

Study shows Cymbalta reduces chronic low back pain

FDA approves Labopharm's OLEPTRO antidepressant for MDD

Daiichi Sankyo initiates Phase III trial of edoxaban in reducing recurrent VTE complications

New study compares two treatment options for clubfoot - Ponseti method and surgical treatment

Penn Medicine experts available to offer medical insight and commentary during 2010 Winter Olympics

New study to investigate preventative programmes for anaemia control in young women

Report: California biomedical industry faces unprecedented challenges

Gene variants protect sexually-abused victims from alcohol dependence, says study

Maximizing quality in clinical trials is emphasized at community workshop

Certain cancer surgeries for low-risk patients may be performed at community hospitals

SNM Clinical Trials Network Workshop: Experts to discuss usage of molecular imaging

Insecticide-treated bed-nets can help in preventing malaria

Multiple ultrasounds may not be necessary for diagnosing DVT in some low-risk patients

New 3D scaffold for stem cell renewal

Research opens new avenues for understanding genetic basis of type 2 diabetes

TGen, Horizon Discovery partner in development of novel cancer cell-lines

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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