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BrainStorm completes registered public offering of common stock

BrainStorm Cell Therapeutics Inc., an innovative developer of adult stem cell technologies and Central Nervous System (CNS) therapeutics, today announced that it completed a registered public offering of 19,818,972 shares of common stock at a price per share of $0.29 and warrants to purchase 14,864,229 shares of common stock at an exercise price of $0.29 per share, representing gross proceeds of $5,747,502.

20 Jul 2012

EMA accepts Pfizer’s bazedoxifene/conjugated estrogens MAA for review

Pfizer Inc. today announced that the European Medicines Agency (EMA) accepted for review the Marketing Authorization Application (MAA) for bazedoxifene/conjugated estrogens (BZA/CE), a potential new medicine for postmenopausal women with a uterus for the treatment of estrogen deficiency symptoms and treatment of osteoporosis in women at risk of fracture.

19 Jul 2012

New UC M program to test comprehensive care physician model

Patients who are frequently hospitalized account for a disproportionate amount of health care spending in the United States. Working with a $6.1 million grant, a new University of Chicago Medicine program will test whether an updated version of the traditional general practitioner can reduce spending while also improving care for these patients.

19 Jul 2012

Marrow aspiration predicts smoldering multiple myeloma progression

Smoldering multiple myeloma patients with bone marrow plasma cell involvement should be treated immediately, say Italian researchers who found these patients are at greatest risk for symptomatic disease.

18 Jul 2012

New roadmap provides expert guidance on how to reduce racial and ethnic health disparities

Major disparities exist along racial and ethnic lines in the United States for various medical conditions, but guidance is scarce about how to reduce these gaps. Now, a new "roadmap" has been unveiled to give organizations expert guidance on how to improve health equity in their own patient populations.

18 Jul 2012

Nanofiber scaffolds regenerate protein components in cartilage repair

Johns Hopkins tissue engineers have used tiny, artificial fiber scaffolds thousands of times smaller than a human hair to help coax stem cells into developing into cartilage, the shock-absorbing lining of elbows and knees that often wears thin from injury or age. Reporting online June 4 in the Proceedings of the National Academy of Sciences, investigators produce an important component of cartilage in both laboratory and animal models.

18 Jul 2012

U.S. News & World Report names Hospital for Special Surgery among 2012 America's Best Hospitals

For the third consecutive year, U.S. News & World Report named Hospital for Special Surgery the top hospital in the country for orthopedics in its 2012 "America's Best Hospitals" survey. Once again, the hospital ranked as a leader in rheumatology at number three in the nation. In addition, neurology was ranked at No. 10.

17 Jul 2012

Pre-concussion baseline testing now available at three Vanderbilt clinics

The Vanderbilt Sports Concussion Center is now offering pre-concussion baseline testing to all community recreational athletes in advance of many high-impact seasonal sports resuming this fall.

17 Jul 2012

New Alzheimer's model derived from skin cells of patients may prove to be more accurate

Researchers at the Alzheimer's Association International Conference 2012 (AAIC 2012) today reported the creation of a new model of Alzheimer's derived from the skin cells of people with the disease that were reprogramed into Alzheimer's brain cells.

17 Jul 2012

U.S. FDA approves Gilead’s Truvada to minimize risk of sexually-acquired HIV infection

Today, the U.S. Food and Drug Administration approved Truvada (emtricitabine/tenofovir disoproxil fumarate), the first drug approved to reduce the risk of HIV infection in uninfected individuals who are at high risk of HIV infection and who may engage in sexual activity with HIV-infected partners. Truto reduce the risk of sexually-acquired HIV infection in adults at high risk.

17 Jul 2012

Scientists discover new way to convert cord blood cells into iNC

For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood and metabolic diseases.

17 Jul 2012

Biomet fourth quarter net sales increase 3% to $739.5 million

Biomet, Inc. announced today preliminary financial results for its fourth quarter and fiscal year ended May 31, 2012. The final results for the three and twelve months ended May 31, 2012 will be made available to the public with the filing of Biomet's Form 10-K for fiscal year 2012 and will include the finalization of a non-cash goodwill and intangible asset impairment charge as further described below and certain income tax accounts.

17 Jul 2012

Gilead receives FDA approval for Truvada to reduce risk of sexually acquired HIV-1 infection

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved once-daily oral Truvada (emtricitabine and tenofovir disoproxil fumarate), in combination with safer sex practices, to reduce the risk of sexually acquired HIV-1 infection in adults at high risk.

17 Jul 2012

Targeting CDK1 pathway may be efficacious for acute myeloid leukemias with FLT3 mutation

Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent mutations observed in acute myeloid leukemias. FLT3 mutants are thought to activate several signaling pathways that contribute to cancer development.

17 Jul 2012

Osteoporosis and sarcopenia: researchers at UMKC receive $8.3 million to study relationship

The University of Missouri-Kansas City has received a five-year, $8.3 million grant from the National Institute on Aging, part of the National Institutes of Health, to study the relationship between osteoporosis (loss of bone density) and sarcopenia (loss of muscle mass) as people age.

16 Jul 2012

Gait disturbances could indicate a decline in cognitive function

Gait disturbances – such as a slowing of walking pace or a more variable stride – could indicate a decline in cognitive function, according to new research studies reported today at the Alzheimer's Association's International Conference 2012 (AAIC 2012).

16 Jul 2012

Rehabilitation after rotator cuff surgery may be partially to blame for high rates of failed healing

A new Hospital for Special Surgery study suggests that the current rehabilitation used for patients undergoing tendon-bone repairs such as rotator cuff repair may be partially to blame for the high rates of failed healing after surgery. Experiments in a rat model of this injury suggest that immobilizing the limb for four to six weeks after surgery, rather than quickly starting physical therapy, improves healing.

16 Jul 2012

$Ankle fracture severity linked to obesity$

Ankle fracture severity linked to obesity

Obese patients experience more severe ankle fractures than individuals with a healthy body mass index, research suggests.

12 Jul 2012

AOSSM to present ten research awards and seven grants during annual meeting in Baltimore

In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine (AOSSM) will present ten research awards and seven grants during its Annual Meeting, July 12-15 in Baltimore, MD. As a leader in orthopaedic sports medicine, AOSSM annually provides more than $350,000 to research initiatives and projects around the country.

12 Jul 2012

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman School of Medicine at the University of Pennsylvania that will be published today in the New England Journal of Medicine.

12 Jul 2012

Bone News and Research

BrainStorm completes registered public offering of common stock

EMA accepts Pfizer’s bazedoxifene/conjugated estrogens MAA for review

New UC M program to test comprehensive care physician model

Marrow aspiration predicts smoldering multiple myeloma progression

New roadmap provides expert guidance on how to reduce racial and ethnic health disparities

Nanofiber scaffolds regenerate protein components in cartilage repair

U.S. News & World Report names Hospital for Special Surgery among 2012 America's Best Hospitals

Pre-concussion baseline testing now available at three Vanderbilt clinics

New Alzheimer's model derived from skin cells of patients may prove to be more accurate

U.S. FDA approves Gilead’s Truvada to minimize risk of sexually-acquired HIV infection

Scientists discover new way to convert cord blood cells into iNC

Biomet fourth quarter net sales increase 3% to $739.5 million

Gilead receives FDA approval for Truvada to reduce risk of sexually acquired HIV-1 infection

Targeting CDK1 pathway may be efficacious for acute myeloid leukemias with FLT3 mutation

Osteoporosis and sarcopenia: researchers at UMKC receive $8.3 million to study relationship

Gait disturbances could indicate a decline in cognitive function

Rehabilitation after rotator cuff surgery may be partially to blame for high rates of failed healing

Ankle fracture severity linked to obesity

AOSSM to present ten research awards and seven grants during annual meeting in Baltimore

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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