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Man-made chemical compound targets and kills tumor cells

A man-made chemical compound called ARC causes tumor cells to die but leaves normal cells unharmed, researchers at the University of Illinois at Chicago report in a study highlighted in the March 15 issue of Cancer Research.

15 Mar 2006

Researchers synthesize nisin in a test tube

Scientists have made nisin, a natural antibiotic used for more than 40 years to preserve food, in a test tube for the first time using nature's toolbox.

13 Mar 2006

University of Michigan researchers target stubborn gram-negative bacteria

Ronald Woodard's team set out looking for a way to kill a stubborn type of bacteria and they succeeded - but not in the way he expected.

9 Mar 2006

Researchers find compound that interferes with the pathogenic effects of Huntington's disease

There is no cure for Huntington's, a neurodegenerative disorder that now afflicts 30,000 Americans, with another 150,000 at risk. The fatal disease, which is genetically inherited, usually strikes in midlife and causes uncontrolled movements, loss of cognitive function and emotional disturbance.

9 Mar 2006

Repligen commences phase 2 trial of RG2417 for bipolar depression

Repligen Corporation today announced that the Company has initiated a Phase 2 clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar depression.

9 Mar 2006

Novel compound may help fight obesity

A new study reveals an attractive new target for therapies aimed at the treatment of obesity and related metabolic disorders, researchers report in the March Cell Metabolism.

9 Mar 2006

Tibotec Pharmaceuticals receives NDA for investigational HIV protease inhibitor

Tibotec Pharmaceuticals has announced that the New Drug Application (NDA) for TMC114, an investigational HIV protease inhibitor, has been accepted for priority review by the United States Food and Drug Administration (FDA).

7 Mar 2006

Potential new treatment for Huntington and Parkinson patients

A potential new treatment for neurodegenerative disorders, which seems to be able to reduce the toxic protein aggregates characteristic of many of these diseases, is published online this week in the journal Proceedings of the National Academy of Sciences.

7 Mar 2006

Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Study looks at how two forms of vitamin E affect the health of animal cells

One of the most powerful antioxidants is truly a double-edged sword, say researchers at Ohio State University who studied how two forms of vitamin E act once they are inside animal cells.

7 Mar 2006

Study reveals most common causes of allergic contact dermatitis

A new Mayo Clinic study reveals the most common causes of allergic contact dermatitis, a skin inflammation resulting in swollen, reddened and itchy skin due to direct contact with an allergen.

7 Mar 2006

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

A recently completed Phase 1 clinical trial of an investigational drug to treat inflammatory bowel disease has demonstrated rapid absorption indicating potential for development as an oral therapy.

6 Mar 2006

Rhodium quinones promise better drugs

By combining a common organic compound with a rare metal, a team of Brown University chemists has created a new class of molecules that have potentially important applications for the pharmaceutical, chemical and energy industries.

1 Mar 2006

Possible link between breast cancer and aluminum salts in deodorants

Chemicals that mimic the body's natural hormone oestrogen are known to affect a woman's risk of breast cancer.

1 Mar 2006

Compound found in marijuana may defend against diabetic retinopathy

A compound found in marijuana won't make you high but it may help keep your eyes healthy if you're a diabetic, researchers say.

1 Mar 2006

Popular painkiller linked to 2000 deaths

$1 million of mesothelioma research funding

The Mesothelioma Applied Research Foundation (MARF) has announced awards of almost $1 million in additional research funding aimed at curing mesothelioma.

24 Feb 2006

M. D. Anderson Cancer Center to investigate CTCE-9908 chemokine CXCR4 antagonist

Chemokine Therapeutics has announced that it has entered into an agreement with The University of Texas M. D. Anderson Cancer Center of Houston, Texas to study the Company's lead anti-cancer compound, CTCE-9908, a chemokine CXCR4 antagonist.

21 Feb 2006

Potential new drug for treating all forms of tuberculosis

An experimental tuberculosis drug may be effective against not only multi drug-resistant forms of the disease but could also be the first compound to treat the latent stage of infection as well. Researchers reported their results at the 2006 ASM Biodefense Research Meeting.

20 Feb 2006

Children given lower doses of adult drugs at risk of harmful side effects

A new study has provided the strongest and most comprehensive evidence yet of the difference between how adults and infants and children process drugs.

19 Feb 2006