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Teen diagnosed with liver cancer explores genetic link to rare cancers

A father-daughter scientific collaboration that began after the daughter was diagnosed with a rare liver cancer has led to an important finding and could have broader implications for many other rare cancers. Their story is being published this week in a top tier journal, Science.

3 Mar 2014

Longer looks: A doctor struggles with new health system; how to reduce end-of-life costs; fighting cancer with aspirin

I know how lucky I am to be a patient who happens to also work in the healthcare system. ... Initially, I had to use antibiotic drops every hour. But my insurance would only cover one three-milliliter bottle every three weeks. Each bottle not covered by insurance cost me $130. ... My own experience makes me fear that for many Americans, health insurance may not necessarily equal health care. Access and cost will still remain barriers - and can be difficult to surmount for many (Dr. Helen Ouyang, 2/24)

28 Feb 2014

Another concern related to low birth weight identified

Researchers have identified another concern related to low birth weight - a difference in how the body reacts to drugs, which may last a person's entire life and further complicate treatment of illnesses or diseases that are managed with medications.

28 Feb 2014

Dampening immune response may encourage lung transplant rejection

Organ transplant patients routinely receive drugs that stop their immune systems from attacking newly implanted hearts, livers, kidneys or lungs, which the body sees as foreign.

27 Feb 2014

Survival rates for bladder cancer in UK are falling, confirms new study

Of the top 10 cancers in the UK, bladder cancer is only one where survival rates have been shown to be getting worse. New figures published this month in the Journal of Clinical Urology confirm in a study of cases of bladder cancer in England over a 19 year period (from 1990 until 2009) that survival rates here in the UK are falling and are worse than in than in other European countries with similar incidence rates.

27 Feb 2014

Organ recovery centers could improve efficiency, reduce costs associated with deceased organ donation

Free-standing organ recovery centers could markedly improve efficiency and reduce costs associated with deceased organ donation, according to a new study published in the American Journal of Transplantation.

27 Feb 2014

Study shows fructose consumption does not contribute to non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is the most common chronic liver disease in developed countries, affecting up to 30 per cent of their populations.

27 Feb 2014

Phase 2 trial results show GPB reduces hepatic encephalopathy episodes in patients with cirrhosis

Phase 2 trial results published in the March issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, suggests the potential for Glycerol Phenylbutyrate (GPB) to reduce hepatic encephalopathy episodes in patients with cirrhosis, with a safety profile similar to placebo.

27 Feb 2014

Research grows "mini-livers" to reduce use of animals in science

Research that has for the first time successfully grown "mini-livers" from adult mouse stem cells has won the UK's international prize for the scientific and technological advance with the most potential to replace, reduce or refine the use of animals in science (the 3Rs).

26 Feb 2014

AMIC provides report on FDA pre-market notification related to brachytherapy cancer product

Advanced Medical Isotope Corporation ("AMIC"), a company engaged in the development, production and distribution of medical isotopes focused on yttrium-90 brachytherapy devices, today announced that it has received a response from the FDA to its pre-market notification to the FDA pursuant to Section 510(k) of the U.S. Food, Drug and Cosmetic Act for its Yttrium-90 (Y-90) RadioGel(tm) patented brachytherapy cancer product.

25 Feb 2014

Moving organ donors to stand-alone facility for retrieving organs is more efficient, lowers costs

Retrieving organs from brain-dead donors is logistically challenging and time consuming in hospitals. Multiple surgical teams often fly to a donor's hospital but frequently face delays in retrieving organs due to crowded operating-room schedules.

25 Feb 2014

FDA approves Iroko Pharmaceuticals’ TIVORBEX capsules

Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, today announced that the U.S. Food and Drug Administration (FDA) has approved TIVORBEX™ (indomethacin) capsules, a nonsteroidal anti-inflammatory drug (NSAID), at 20 mg and 40 mg doses for the treatment of mild to moderate acute pain in adults.

25 Feb 2014

Researchers develop new technology that reveals secrets of cellular memory

Cells in our body are constantly dividing to maintain our body functions. At each division, our DNA code and a whole machinery of supporting components has to be faithfully duplicated to maintain the cell's memory of its own identity.

25 Feb 2014

New research shows that saturated fat builds more fat, less muscle than polyunsaturated fat

New research from Uppsala University shows that saturated fat builds more fat and less muscle than polyunsaturated fat. This is the first study on humans to show that the fat composition of food not only influences cholesterol levels in the blood and the risk of cardiovascular disease but also determines where the fat will be stored in the body.

25 Feb 2014

Study highlights novel reprogramming method that offers new hope for treating liver failure

The power of regenerative medicine now allows scientists to transform skin cells into cells that closely resemble heart cells, pancreas cells and even neurons. However, a method to generate cells that are fully mature-a crucial prerequisite for life-saving therapies-has proven far more difficult.

24 Feb 2014

Scientists discover how viral DNA of HBV can be degraded in cell nucleus

Scientists from the Helmholtz Zentrum München and the Technische Universität München have discovered how the viral DNA of the hepatitis B virus (HBV) can be degraded in the cell nucleus of liver cells, consequently allowing the virus to be eliminated.

24 Feb 2014

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Patients with HPV-positive squamous cell carcinoma of the oropharynx (SCCOP) had a longer time to development of distant metastasis (DM) after initial treatment, and had more metastatic sites in more atypical locations compared to HPV-negative patients, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

Bayer enrolls patients for Phase III trial of Stivarga (regorafenib) tablets in colorectal cancer

Bayer HealthCare today announced that the company has begun to enroll patients in the COAST trial studying Stivarga® (regorafenib) tablets in colorectal cancer (CRC) patients with resected liver metastases.

20 Feb 2014

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

The Cystinosis Research Foundation awarded $2,153,048 in 2013 to researchers investigating better treatments and a cure for cystinosis, a rare metabolic and genetic disease that afflicts about 500 children and young adults in the United States and 2,000 worldwide.

19 Feb 2014

Study examines brain activity of alcohol-dependent women

A new Indiana University study that examines the brain activity of alcohol-dependent women compared to women who were not addicted found stark and surprising differences, leading to intriguing questions about brain network functions of addicted women as they make risky decisions about when and what to drink.

19 Feb 2014

Liver News and Research

Teen diagnosed with liver cancer explores genetic link to rare cancers

Longer looks: A doctor struggles with new health system; how to reduce end-of-life costs; fighting cancer with aspirin

Another concern related to low birth weight identified

Dampening immune response may encourage lung transplant rejection

Survival rates for bladder cancer in UK are falling, confirms new study

Organ recovery centers could improve efficiency, reduce costs associated with deceased organ donation

Study shows fructose consumption does not contribute to non-alcoholic fatty liver disease

Phase 2 trial results show GPB reduces hepatic encephalopathy episodes in patients with cirrhosis

Research grows "mini-livers" to reduce use of animals in science

AMIC provides report on FDA pre-market notification related to brachytherapy cancer product

Moving organ donors to stand-alone facility for retrieving organs is more efficient, lowers costs

FDA approves Iroko Pharmaceuticals’ TIVORBEX capsules

Researchers develop new technology that reveals secrets of cellular memory

New research shows that saturated fat builds more fat, less muscle than polyunsaturated fat

Study highlights novel reprogramming method that offers new hope for treating liver failure

Scientists discover how viral DNA of HBV can be degraded in cell nucleus

Study: Recurrence of SCCOP may differ in HPV-positive and HPV-negative patients

Bayer enrolls patients for Phase III trial of Stivarga (regorafenib) tablets in colorectal cancer

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

Study examines brain activity of alcohol-dependent women

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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