Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

UT Southwestern research could lead to new ways of controlling gene regulation

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

3 Feb 2023

Targeting a single enzyme can kill prostate cancer cells

For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα.

3 Feb 2023

Study identifies a drug candidate for the treatment of fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

3 Feb 2023

The effectiveness of intranasal COVID-19 vaccination in healthy adults

A recent study discusses the safety profiles and immunogenicity of the nasal BBV154 COVID-19 vaccine in healthy adults.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

In all living organisms, DNA replication is essential to ensure the genetic fidelity of the next generation. However, bacteria can also transfer genetic information horizontally to other bacteria.

3 Feb 2023

Are plasma levels of axonal damage and neuronal degeneration makers altered in COVID-19 patients without major neurological manifestations?

A recent study evaluated whether plasma levels of NfL, T-tau, and GFAP changed in SARS-CoV-2-infected patients with or without major neurological manifestations.

3 Feb 2023

The human body develops strategies to prevent the immune response from overshooting its mark

The signaling molecules of the immune system should trigger a response only where necessary. To prevent a life-threatening spread to the rest of the body, connective tissue can absorb these molecules like a sponge.

3 Feb 2023

SARS-CoV-2 infections on French mink farms after one year of COVID-19

A new paper, which appears on the bioRxiv* preprint server, describes the investigation of all French mink farms towards the end of 2020. This was to maximize the chances of identifying SARS-CoV-2 infection in these animals at any time over the past year.

3 Feb 2023

What are the predictors of in-hospital mortality in cancer patients with COVID-19?

A new study in PLoS ONE aimed to analyze the variables associated with in-hospital mortality in COVID-19-positive cancer patients who were presented to the ED.

3 Feb 2023

The impact of viral infections on the human endocrine system

Researchers briefly outlined how viral infections trigger endocrinopathies in humans.

3 Feb 2023

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against SARS-CoV-2.

3 Feb 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

Pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant

Researchers examined the histopathological condition of the lungs of patients who died from COVID-19 caused by the SARS-CoV-2 Delta (B.1.617.2) variant.

3 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

New electrochemical sensing technology enables detection of SARS-CoV-2 antigen-specific antibodies

Not all SARS-CoV-2 infections are created equal. We have learned this through multiple virus waves are taking their toll on the world's population.

3 Feb 2023

Researchers document link between higher risk of maternal mortality and sickle cell disease

Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it.

3 Feb 2023

Improving CAR-based-immunotherapies using a molecular anchor

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective.

3 Feb 2023

Oncodesign Services looks to the future

As Oncodesign evolves into Oncodesign Services and begins its journey as an independent business, CEO Fabrice Viviani explains his hopes and plans for the company’s future.

From Oncodesign Services 3 Feb 2023

Protein News and Research

Further Reading

UT Southwestern research could lead to new ways of controlling gene regulation

Targeting a single enzyme can kill prostate cancer cells

Study identifies a drug candidate for the treatment of fatty liver disease

The effectiveness of intranasal COVID-19 vaccination in healthy adults

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Researchers discover a new hexameric structure of the RepB protein and how it binds to DNA

Are plasma levels of axonal damage and neuronal degeneration makers altered in COVID-19 patients without major neurological manifestations?

The human body develops strategies to prevent the immune response from overshooting its mark

SARS-CoV-2 infections on French mink farms after one year of COVID-19

What are the predictors of in-hospital mortality in cancer patients with COVID-19?

The impact of viral infections on the human endocrine system

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

The relationship between natural plant extracts and SARS-CoV-2

Pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

New electrochemical sensing technology enables detection of SARS-CoV-2 antigen-specific antibodies

Researchers document link between higher risk of maternal mortality and sickle cell disease

Improving CAR-based-immunotherapies using a molecular anchor

Oncodesign Services looks to the future

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