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Rexahn Pharmaceuticals signs license agreement with UMB for novel drug delivery platform

Rexahn Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, announced today that it has signed an exclusive license agreement with the University of Maryland, Baltimore for a novel drug delivery platform, Nano-Polymer-Drug Conjugate Systems.

17 Jul 2013

TAp73 protein frequently overexpressed in wide range of human tumors

They say you can pick your friends, but not your family. The same may hold true for related proteins. The protein TAp73 is a relative of the well-known, tumor-suppressor protein p53. It shares extensive common gene sequences with p53 and, as suggested by some previous studies, it may function similar to p53 to prevent tumor formation.

17 Jul 2013

Research shows that rates of coronary heart disease are higher with longer duration of obesity

In a study of adults recruited and followed up over the past 3 decades in the United States, longer duration of overall and abdominal obesity beginning in young adulthood was associated with higher rates of coronary artery calcification, a subclinical predictor of coronary heart disease, according to a study in the July 17 issue of JAMA.

17 Jul 2013

Progress made in understanding Pulmonary Arterial Hypertension

The next step has been made into isolating the origin of cells linked to the progressive disorder Pulmonary Arterial Hypertension.

17 Jul 2013

Scientists develop histology expression predictor for most common types of lung cancer

Knowing what type of lung cancer a patient has is critical to determine which drug will work best and which therapies are safest in the era of personalized medicine. Key to making that judgment is an adequate tumor specimen for the pathologist to determine the tumor's histology, a molecular description of a tumor based on the appearance of cells under a microscope.

17 Jul 2013

Smokers who seem healthy have damaged airway cells similar to cells found in aggressive lung cancer

Smokers who've received a clean bill of health from their doctor may believe cigarettes haven't harmed their lungs. However, researchers at Weill Cornell Medical College have found that even smokers who seem healthy have damaged airway cells, with characteristics similar to cells found in aggressive lung cancer.

17 Jul 2013

Magnets could be used for directing stem cells, may help treat heart and vascular diseases

Magnets could be a tool for directing stem cells' healing powers to treat conditions such as heart disease or vascular disease.

17 Jul 2013

Largest data set of cancer-specific genetic variations generated by NCI scientists

Scientists at the National Cancer Institute have generated a data set of cancer-specific genetic variations and are making these data available to the research community, according to a study published in Cancer Research, a journal of the American Association for Cancer Research.

16 Jul 2013

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

As surgeons who take care of cancer patients, we have observed a troubling association between patients who suffer from infections after surgery and the rapid spread of their cancer. We have reported this in lung cancer patients, and others have made these observations in a variety of different cancers. However, the mechanisms responsible for this association are still poorly understood.

16 Jul 2013

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Companion test also approved to identify appropriate patients The U.S. Food and Drug Administration today approved Gilotrif (afatinib) for patients with late stage (metastatic) non-small cell lung cancer (NSCLC) whose tumors express specific types of epidermal growth factor receptor (EGFR) gene mutations, as detected by an FDA-approved test. Lung cancer is the leading cause of cancer-related death among men and women.

16 Jul 2013

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings suggest that these naturally produced mutations are just as powerful as known cancer-causing agents in producing tumors.

15 Jul 2013

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

Infrared light allows characterization of pathogens

The bacterium Staphylococcus aureus (S. aureus) is commonly found in nature and frequently colonizes the skin and the upper respiratory tract of humans. A healthy immune system can fight the microorganism but once the immune system is weakened the pathogen can spread and lead to life-threatening diseases of the lungs, the heart and other organs.

15 Jul 2013

Researchers discover that APOBEC3B is important cancer mutagen

Researchers at the University of Minnesota have discovered that a human antiviral enzyme causes DNA mutations that lead to several forms of cancer.

15 Jul 2013

Research: Sharp edged graphene sheets can easily pierce cell membranes

Researchers from Brown University have shown how tiny graphene microsheets - ultra-thin materials with a number of commercial applications - could be big trouble for human cells.

12 Jul 2013

Global recruitment drive to bring best cancer experts to Manchester now underway

A global recruitment drive to bring 20 of the world's best cancer experts and their teams to Manchester, in the United Kingdom, is now underway.

From The University of Manchester 12 Jul 2013

Comprehensive analysis of disease burden in US

In nearly every major cause of premature death - from ischemic heart disease to diabetes to interpersonal violence - the United States trails its economic peers, according to new research from a global collaborative of scientists led by the Institute for Health Metrics and Evaluation at the University of Washington.

12 Jul 2013

Infant vaccination against pneumonia helps protect elderly

Children who receive a vaccine to prevent blood and ear infections, appear to be reducing the spread of pneumonia to the rest of the population, especially their grandparents and other older adults.

11 Jul 2013

Study shows cigarette smoke inhibits activity of key genes that protect heart and lungs

New insights into why obese cigarette smokers experience a high risk of heart disease suggest that cigarette smoke affects the activity of hundreds of key genes that both protect the heart and lungs and expose them to damage.

11 Jul 2013

Prolonged exposure to low levels of air pollution boosts lung cancer risk

Prolonged exposure to particulate air pollution increases the risk of lung cancer (particularly adenocarcinoma) even at levels below the European Union limit values, according to one of the largest studies of its kind published in The Lancet Oncology.

11 Jul 2013

Lungs News and Research

Rexahn Pharmaceuticals signs license agreement with UMB for novel drug delivery platform

TAp73 protein frequently overexpressed in wide range of human tumors

Research shows that rates of coronary heart disease are higher with longer duration of obesity

Progress made in understanding Pulmonary Arterial Hypertension

Scientists develop histology expression predictor for most common types of lung cancer

Smokers who seem healthy have damaged airway cells similar to cells found in aggressive lung cancer

Magnets could be used for directing stem cells, may help treat heart and vascular diseases

Largest data set of cancer-specific genetic variations generated by NCI scientists

White blood cells and the spread of cancer: an interview with Drs. Lorenzo Ferri and Jonathan Cools-Lartigue, McGill University

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

Infrared light allows characterization of pathogens

Researchers discover that APOBEC3B is important cancer mutagen

Research: Sharp edged graphene sheets can easily pierce cell membranes

Global recruitment drive to bring best cancer experts to Manchester now underway

Comprehensive analysis of disease burden in US

Infant vaccination against pneumonia helps protect elderly

Study shows cigarette smoke inhibits activity of key genes that protect heart and lungs

Prolonged exposure to low levels of air pollution boosts lung cancer risk

The ultimate guide to lung research tools and protocols eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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