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DMET genotyping platform screens for 1256 genetic variations in 170 genes

It's the ultimate goal in the treatment of cancer: tailoring a person's therapy based on his or her genetic makeup. While a lofty goal, scientists are steadily moving forward, rapidly exploiting new technologies. Researchers at Georgetown Lombardi Comprehensive Cancer Center report a significant advance in this field of research using a new chip that looks for hundreds of mutations in dozen of genes.

29 Dec 2009

Kidney transplantation saves life

For more than 20 years Delores Evans battled diabetes, high blood pressure and, finally, kidney failure. By 2008 she needed a new kidney to stay alive, but she never could have imagined the circumstances that brought it about.

29 Dec 2009

Study explains how semaphorin gene regulates synapse formation

By combining a research technique that dates back 136 years with modern molecular genetics, a Johns Hopkins neuroscientist has been able to see how a mammal's brain shrewdly revisits and reuses the same molecular cues to control the complex design of its circuits.

29 Dec 2009

Study suggests genetic variations predispose African-Americans to diabetes

For years, scientists have tried to determine the basis for discrepancies between race and the predisposition for development of diseases such as type II diabetes and cardiovascular disease. Could factors such as differences in lifestyle or access to health care play a role, or is there something else in play?

29 Dec 2009

First animal model for studying schizophrenia

Scientists have created what appears to be a schizophrenic mouse by reducing the inhibition of brain cells involved in complex reasoning and decisions about appropriate social behavior.

29 Dec 2009

Defects in protein-secretion machinery linked to neural tube closure

Spinal cord disorders like spina bifida arise during early development when future spinal cord cells growing in a flat layer fail to roll up into a tube. In the Dec. 6 issue of Nature Cell Biology, researchers from the Johns Hopkins University School of Medicine team with colleagues at the University of California, Berkeley to report a never-before known link between protein transport and mouse spinal cord development, a discovery that opens new doors for research on all spinal defects.

29 Dec 2009

New evidence suggests amyloid beta plays a critical role in synaptic failure

The early stages of Alzheimer's disease are thought to occur at the synapse, since synapse loss is associated with memory dysfunction. Evidence suggests that amyloid beta (Aβ) plays an important role in early synaptic failure, but little has been understood about Aβ's effect on the plasticity of dendritic spines.

29 Dec 2009

The Medical College of Wisconsin licenses novel molecular imaging technology to GE Healthcare

A novel molecular imaging technology aimed at rapid diagnosis of cell death in organs such as the brain and heart has been licensed by The Medical College of Wisconsin to GE Healthcare. Under the license GE will further evaluate and develop the technology and will have an option to commercialize the technology. The technology, using imaging probes with a radiopharmaceutical compound, was invented by Ming Zhao, Ph.D., assistant professor of biophysics.

29 Dec 2009

American Diabetes Association recommends A1C test for diagnosing diabetes and identifying pre-diabetes

The American Diabetes Association's new Clinical Practice Recommendations being published as a supplement to the January issue of Diabetes Care call for the addition of the A1C test as a means of diagnosing diabetes and identifying pre-diabetes. The test has been recommended for years as a measure of how well people are doing to keep their blood glucose levels under control.

29 Dec 2009

BHS implements Greenway Medical Technologies' fully-integrated EHR solution

Greenway Medical Technologies, Inc. today announced the deployment of its fully-integrated electronic health record (EHR), practice management and interoperability solution, PrimeSuite®, into Palm Beach County, Florida's Bethesda Healthcare System (BHS) and its flagship hospital, Bethesda Memorial Hospital. BHS operates the 401-bed hospital as well as specialty practices that include family practice, internal medicine, cardiovascular surgery, neurology and orthopedics.

29 Dec 2009

Research suggests common mechanism is associated with different human diseases

Inherited mutations in voltage-gated sodium channels (Navs) are associated with many different human diseases, including genetic forms of epilepsy and chronic pain. Theodore Cummins and colleagues, at Indiana University School of Medicine, Indianapolis, have now determined the functional consequence of three such mutations.

29 Dec 2009

Researcher Avinash Patwardhan wins top honor from North American Spine Society

Researcher Avinash Patwardhan, Ph.D., of Loyola University Health System, a leading expert on the biomechanics of the human spine, has won a top honor from the North American Spine Society.

29 Dec 2009

Health Sciences Group to operate under the Healing Center-Livingston

Health Sciences Group, Inc. would like to announce that it has completed a licensing agreement with The Healing Center of Montana for the territory of Livingston County, Montana for purposes of operating a medical marijuana collective and distribution center for medical marijuana patients as pertains to Montana state and Livingston County law.

28 Dec 2009

Nanoscaffolds could play a central role in tissue and organ reconstruction

Researchers from the University of Hong Kong and the Massachusetts Institute of Technology have published a study in the current issue of Cell Transplantation (18:9), now freely available on line at http://www.ingentaconnect.com/content/cog/ct, that explores ways to successfully keep stem cells "forever young" during implantation by slowing their growth, differentiation and proliferation.

28 Dec 2009

Sudden worldwide increase in antibiotic-resistant bacterium, a cause for concern

A sudden worldwide increase in an antibiotic-resistant bacterium is cause for concern, according to a review in f1000 Medicine Reports.

28 Dec 2009

Hunger hormone can intensify high-fat food consumption

The premise that hunger makes food look more appealing is a widely held belief - just ask those who cruise grocery store aisles on an empty stomach, only to go home with a full basket and an empty wallet.

28 Dec 2009

CAPG lauds passage of federal health care reform legislation

“This is the most sweeping health reform legislation since the enactment of Medicare. It will provide an extraordinary opportunity to make a very real difference in the lives of millions of people. This comprehensive bill package addresses major areas in need of change, including expanding coverage to nearly all Americans, eliminating various unfair insurance practices, and beginning to transform our dysfunctional delivery system.”

28 Dec 2009

Brain circuit that holds the memory discovered

Ben W. Strowbridge, PhD, associate professor of neuroscience and physiology/biophysics, and Phillip Larimer, PhD, a MD/PhD student in the neurosciences graduate program at Case Western Reserve University School of Medicine, are the first to create stimulus-specific sustained activity patterns in brain circuits maintained in vitro.

28 Dec 2009

CtIP protein plays a critical role in DNA repair

La Jolla, CA-In order to preserve our DNA, cells have developed an intricate system for monitoring and repairing DNA damage. Yet precisely how the initial damage signal is converted into a repair response remains unclear. Researchers at the Salk Institute for Biological Studies have now solved a crucial piece of the complex puzzle.

28 Dec 2009

Community Health Systems' subsidiary enters into affiliation agreement with Rockwood Clinic

Community Health Systems, Inc. announced today that a subsidiary has entered into an affiliation agreement with Rockwood Clinic, P.S., a multi-specialty clinic with 32 locations across the Inland Northwest region of the State of Washington.

28 Dec 2009