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Over three hundred proteins investigated to understand the mechanism that allows limbs to regenerate

The most comprehensive study to date of the proteins in a species of salamander that can regrow appendages may provide important clues to how similar regeneration could be induced in humans.

15 Dec 2009

Risks and benefits of CT scans

Doses of radiation from commonly performed computed tomography (CT) scans vary widely, appear higher than generally believed and may contribute to an estimated tens of thousands of future cancer cases, according to two reports in the December 14/28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

15 Dec 2009

Mutant ATPase blocks autophagy partway and causes multi-tissue degenerative disease

It's important to finish what you start, say Jeong-Sun Ju and researchers from Washington University School of Medicine, St. Louis. In the December 14, 2009 issue of the Journal of Cell Biology (www.jcb.org), Ju et al. reveal how a mutant ATPase blocks autophagy partway through to cause a multi-tissue degenerative disease.

15 Dec 2009

Increased physical activity decreases risk of colorectal cancer

Increased physical activity appears to be associated with a lower risk of cancer-specific and overall death in men with a history of colorectal cancer that has not spread to other parts of the body, according to a report in the December 14/28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

15 Dec 2009

Findings suggest variations in accelerated aging disorders

UT Southwestern Medical Center researchers have provided the most extensive account to date of the unique observable characteristics seen in patients with an extremely rare premature aging syndrome.

15 Dec 2009

Study to determine link between insulin glargine and cancer

Type 2 diabetes and obesity are linked to an increased risk of certain cancers. Recently published studies suggested that insulin glargine (a synthetic insulin preparation marketed under the trade name Lantus), may be associated with a higher risk of certain cancers than other insulins or oral glucose lowering medications. However, these studies were unable to control for important factors such as obesity that may have driven the association.

15 Dec 2009

Enrolment for pivotal Phase II/III trial of C-Cure completed ahead of schedule

Cardio3 BioSciences, a leading Belgian biotechnology company specialising in cell-based therapies for the treatment of cardiovascular diseases, announced today that it has completed, two months ahead of schedule, enrolment in the first stage of its pivotal Phase II/III trial of C-Cure, a unique stem cell therapy for heart failure.

15 Dec 2009

Freie Universität professor receives ERC grant for bacterial biofilm formation study

Prof. Dr. Regine Hengge at the Department of Biology, Chemistry, and Pharmacy at Freie Universität Berlin has been awarded funding from the European Research Council (ERC) for her research project to investigate the formation of bacterial biofilms. Hengge will receive an ERC Advanced Investigator Grant in an amount of up to two million euros.

15 Dec 2009

New study to help researchers develop highly effective drug for MLL

A new study could point the way to the development of better drugs to fight a deadly form of childhood leukemia called mixed-lineage leukemia (MLL).

15 Dec 2009

OU lab completes studies on new type of training technique

Bemben's lab at the university is currently only one of four labs outside of Japan that has been working with the KAATSU-Master training system, testing the effectiveness of reducing blood flow to exercising muscle.

15 Dec 2009

Seattle Genetics announces collaboration to globally develop and commercialize brentuximab vedotin

Seattle Genetics, Inc. and Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today jointly announced that Seattle Genetics and Millennium have entered into an agreement to globally develop and commercialize brentuximab vedotin (SGN-35).

15 Dec 2009

Breakthrough procedure yields a number of medical possibilities for dental stem cells

BioEDEN, the world-leader in dental stem cell extraction and storage, is celebrating the first successful human medical trial using stem cells from teeth.

15 Dec 2009

FDA publishes cGMPs for PET drugs

The U.S. Food and Drug Administration (FDA) announced publication of a final regulation on current good manufacturing practices (cGMPs) for the production of positron emission tomography (PET) drugs, as well as a guidance document describing acceptable approaches that would enable PET drug producers to meet the requirements in the proposed regulation.

15 Dec 2009

Scientists identify protein switch that helps prevent liver cancer

A team of scientists from the UC San Diego School of Medicine and Osaka University in Japan have identified a protein switch that helps prevent liver damage, including inflammation, fibrosis and cancer. The findings suggest that a better understanding of how the protein, TAK1, works could lead to new insights into the development of liver disease and cancer.

15 Dec 2009

Study says children are still bombarded with TV ads for unhealthy food choices

A new study released Monday, Dec. 14, in Washington, D.C., criticizes the nation's food and beverage industry for failing to shift their marketing efforts aimed at children. The report said television advertising continues to contribute to epidemic levels of obesity, despite industry promises of reform.

15 Dec 2009

Study explores comorbidity of medical complaints and insomnia symptoms in school-aged children

A study in the Dec. 15 issue of the Journal of Clinical Sleep Medicine indicates that significant associations exist between parent-reported insomnia symptoms and medical complaints of gastrointestinal regurgitation and headaches in young school-aged children.

15 Dec 2009

Update on new clinical developments and other initiatives related to Ceplene

EpiCept Corporation today provided an update on new clinical developments and other initiatives related to Ceplene® (histamine dihydrochloride), the Company’s therapy approved in the European Union for the remission maintenance and prevention of relapse of patients with acute myeloid leukemia (AML) in first remission.

15 Dec 2009

Tel Aviv University researchers unravel the mysteries of DNA packaging

The RNA "spools" that make up DNA in our genes need careful editing, too. Genes are composed of meaningful sequences, called exons, separated by meaningless junk sections called introns.

15 Dec 2009

ProChon Biotech announces expansion of BioCart Cartilage Regeneration System study

ProChon Biotech, Ltd., an innovator of tissue regenerative technologies that are being developed to relieve pain and restore the mobility and quality of life for sufferers of articular cartilage injuries, today announced a significant expansion of its clinical study of the BioCart™ Cartilage Regeneration System.

15 Dec 2009

Study may pave way for effective drug development for childhood leukemia

A new study could point the way to the development of better drugs to fight a deadly form of childhood leukemia called mixed-lineage leukemia (MLL).

15 Dec 2009

Medicine News and Research

Over three hundred proteins investigated to understand the mechanism that allows limbs to regenerate

Risks and benefits of CT scans

Mutant ATPase blocks autophagy partway and causes multi-tissue degenerative disease

Increased physical activity decreases risk of colorectal cancer

Findings suggest variations in accelerated aging disorders

Study to determine link between insulin glargine and cancer

Enrolment for pivotal Phase II/III trial of C-Cure completed ahead of schedule

Freie Universität professor receives ERC grant for bacterial biofilm formation study

New study to help researchers develop highly effective drug for MLL

OU lab completes studies on new type of training technique

Seattle Genetics announces collaboration to globally develop and commercialize brentuximab vedotin

Breakthrough procedure yields a number of medical possibilities for dental stem cells

FDA publishes cGMPs for PET drugs

Scientists identify protein switch that helps prevent liver cancer

Study says children are still bombarded with TV ads for unhealthy food choices

Study explores comorbidity of medical complaints and insomnia symptoms in school-aged children

Update on new clinical developments and other initiatives related to Ceplene

Tel Aviv University researchers unravel the mysteries of DNA packaging

ProChon Biotech announces expansion of BioCart Cartilage Regeneration System study

Study may pave way for effective drug development for childhood leukemia

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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