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New method allows the discovery of specific inhibitors of lactate transporter

Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate transporter associated with cancer and other disease areas.

28 Jul 2023

Study finds that patients with systemic autoimmune rheumatic diseases had a lower antibody response than healthy controls after Omicron infection

Study investigated if patients with systemic autoimmune rheumatic diseases (SARDs) have a reduced immunological response.

27 Jul 2023

Study provides valuable insights into the UV susceptibility of SARS-CoV-2 omicron variants

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its new variants has created a need for effective disinfection technologies to protect against harmful pathogens.

27 Jul 2023

KIAA0930 could be a novel therapeutic target for cancer cachexia

A new research paper was published in Oncotarget's Volume 14 on July 20, 2023, entitled, "The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells."

26 Jul 2023

Uruguay needs to increase cervical cancer screening rates to reduce mortality, report reveals

Research from the Registro Nacional de Cáncer notes that Uruguay has the highest cancer incidence and mortality rates in Latin America. In particular, cervical cancer is the third leading cause of cancer related morbidity among Uruguay's female population.

26 Jul 2023

STEMCELL Technologies celebrates 30 years with unprecedented annual growth

STEMCELL Technologies, Canada’s largest biotechnology company, is marking its 30th year of accelerating research into cancer and other diseases by celebrating its culture of collaboration, curiosity, and discovery.

26 Jul 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

New assay identifies patients with altered p300/CBP acetylation in castration-resistant prostate cancer

A new research paper was published in Oncotarget's Volume 14 on July 20, 2023, entitled, "Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells."

24 Jul 2023

Using bacteriophages to treat bladder infections

About one in two women are affected by cystitis during her lifetime, and many suffer from recurrent urinary tract infections.

21 Jul 2023

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions are developing a strategy to predict the response of triple negative breast cancer (TNBC) to chemotherapy, which would be a valuable tool for physicians deciding on the treatment with better probability of success on an individual basis.

21 Jul 2023

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

Researchers investigated early biomarkers of post-acute sequelae of SARS-CoV-2 infection in individuals intensively sampled during the acute phase of COVID-19.

20 Jul 2023

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Researchers evaluated the impact of Lewy body (LB) positivity (+) on clinical outcomes such as cognition and smell among cognitively.

20 Jul 2023

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

Researchers examine plasma interleukin-6, vascular cell adhesion molecule-1, and C-reactive protein levels in pregnant women with preeclampsia.

20 Jul 2023

Arrayjet announces collaboration with Chemspace to augment its small molecule microarray services for drug discovery

Arrayjet, a leading provider of inkjet liquid-handling solutions, today announced that it has partnered with Chemspace, the largest online catalogue of small molecules and biologics, to augment and streamline the Company’s small molecule microarray (SMM) service offering.

From Arrayjet Ltd 19 Jul 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

Merck awards 2023 Future Insight Prize for research into air sensor to detect pandemic pathogens

Merck KGaA, Darmstadt, Germany, awarded its 2023 Future Insight Prize to Khalid Salaita, professor of chemistry at Emory University. The award comes with $540,000 to fund the next phase of research into an air sensor that can continuously monitor indoor spaces for pathogens that can cause pandemics.

17 Jul 2023

Seroepidemiology study suggests EV-A71 vaccine effective in Guangzhou, China

Enterovirus A71 (EV-A71) is a significant hand-foot-mouth disease (HFMD) etiology. The inactivated EV-A71 vaccines were approved in China in 2016.

17 Jul 2023

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Researchers examined the association between antidrug antibodies and the response to treatments for rheumatoid arthritis.

17 Jul 2023

Assay News and Research

New method allows the discovery of specific inhibitors of lactate transporter

Study finds that patients with systemic autoimmune rheumatic diseases had a lower antibody response than healthy controls after Omicron infection

Study provides valuable insights into the UV susceptibility of SARS-CoV-2 omicron variants

KIAA0930 could be a novel therapeutic target for cancer cachexia

Uruguay needs to increase cervical cancer screening rates to reduce mortality, report reveals

STEMCELL Technologies celebrates 30 years with unprecedented annual growth

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

Tumor-derived GDF-15 suppresses immunotherapy response

New assay identifies patients with altered p300/CBP acetylation in castration-resistant prostate cancer

Using bacteriophages to treat bladder infections

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

Arrayjet announces collaboration with Chemspace to augment its small molecule microarray services for drug discovery

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Eternal youth? Chemical cocktails prove effective in cell age reversal

Merck awards 2023 Future Insight Prize for research into air sensor to detect pandemic pathogens

Seroepidemiology study suggests EV-A71 vaccine effective in Guangzhou, China

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Understanding the DNA Damage Response in Innate Immunity eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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