Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Mount Sinai physician-scientists have found that a novel therapy for the bone marrow cancer myelofibrosis is safe and well-tolerated and is associated with modest improvements in patients in a Phase 1b clinical trial.

12 Dec 2021

UEA researchers reveal how immune cells use the body’s fat stores to fight infection

New research from the University of East Anglia and Quadram Institute reveals how our immune cells use the body’s fat stores to fight infection.

9 Dec 2021

New genetic technology for gene expression analysis of cancer cells

In this interview, News-Medical speaks to Dr. Rong Lu about her recent research into the development of a new genetic technology for gene expression analysis of cancer cells.

3 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

For older adults, smelling the roses may be more difficult

The reports from covid-19 patients are disconcerting. Only a few hours before, they were enjoying a cup of pungent coffee or the fragrance of flowers in a garden. Then, as if a switch had been flipped, those smells disappeared.

1 Dec 2021

COVID-19 infections in the fully vaccinated are rare but are common in people with weak immune systems

A real-world retrospective cohort study involving nearly 1.2 million people shows COVID-19 infections in the 'fully' vaccinated are rare but are more common and severe in people with weaker immune systems.

30 Nov 2021

NYU Langone opens new state-of-the-art center to treat patients with blood cancers

NYU Langone Health's Laura and Isaac Perlmutter Cancer Center opened a new state-of-the-art center to treat people with blood cancers, including leukemia, lymphoma, and multiple myeloma.

29 Nov 2021

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Researchers investigated the immunogenicity of a novel adjuvant comprised of a modified porous silicon microparticle for the SARS-CoV-2 S protein RBD subunit vaccine.

29 Nov 2021

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

Clonal hematopoiesis, a condition in which mutations associated with blood cancers are found in the blood of healthy people, is common with aging.

22 Nov 2021

AI could help better diagnose blood diseases

How can we better diagnose blood diseases? A research group led by Helmholtz Munich aims to answer this question with artificial intelligence (AI).

22 Nov 2021

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing "stem" cells that line and penetrate a mouse skull.

18 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

Study improves understanding of the link between obesity and gum disease

Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new University at Buffalo research that sought to improve understanding of the connection between obesity and gum disease.

12 Nov 2021

NanoTCE technology shows promise for treatment of acute myeloid leukemia

Oncotarget published "Nanoparticle T cell engagers for the treatment of acute myeloid leukemia" which reported that Acute myeloid leukemia (AML) is the most common type of leukemia and has a 5-year survival rate of 25%.

12 Nov 2021

Rare disease diagnosis by 100,000 genomes pilot

A team of researchers conducted a pilot study that enrolled families and undertook detailed clinical phenotyping of the proband to evaluate the effect of the whole genome sequencing approach on a genetic diagnosis of rare conditions by the NHS in the UK.

12 Nov 2021

Researchers identify gene expression involved in cancer progression and chemotherapy resistance

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

11 Nov 2021

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.

11 Nov 2021

Whole senome sequencing can effectively secure a diagnosis for people with rare diseases

A world-first scientific study, published today in the New England Journal of Medicine, has shown that whole genome sequencing can uncover new diagnoses for people across the broadest range of rare diseases investigated to date and could deliver enormous benefits across the NHS.

10 Nov 2021

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy.

10 Nov 2021

Bone Marrow News and Research

Further Reading

Novel immunotherapy shows promise for children, young adults with recurrent AML

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

UEA researchers reveal how immune cells use the body’s fat stores to fight infection

New genetic technology for gene expression analysis of cancer cells

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

For older adults, smelling the roses may be more difficult

COVID-19 infections in the fully vaccinated are rare but are common in people with weak immune systems

NYU Langone opens new state-of-the-art center to treat patients with blood cancers

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Donor cells with clonal hematopoiesis may improve bone marrow transplant outcomes

AI could help better diagnose blood diseases

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

What genes affect the COVID-19 gender imbalance?

Study improves understanding of the link between obesity and gum disease

NanoTCE technology shows promise for treatment of acute myeloid leukemia

Rare disease diagnosis by 100,000 genomes pilot

Researchers identify gene expression involved in cancer progression and chemotherapy resistance

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

Whole senome sequencing can effectively secure a diagnosis for people with rare diseases

New method of stem cell transplantation may eliminate the need for radiation or chemotherapy

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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