CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

Terrifying brush with death drives doctor to fight for patients

The searing abdominal pain came on suddenly while Dr. Rana Awdish was having dinner with a friend. Soon she was lying in the back seat of the car racing to Henry Ford Hospital in Detroit, where Awdish was completing a fellowship in critical care.

2 Jan 2018

PENTAX Medical launches new, FDA-cleared C.A.P. HD Duodenoscope in the U.S.

PENTAX Medical, an industry leader in endoscopic imaging, announced the U.S. launch of its new C.A.P. HD Duodenoscope (ED34-i10T), the first FDA-cleared duodenoscope with a disposable distal cap.

22 Dec 2017

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Many breast cancer patients do not feel fully informed about their treatment options, say researchers

A research team in the U.S. has found that most women who undergo breast cancer operations do not feel fully informed about their treatment options when they decide on which procedure to undergo.

18 Dec 2017

Researchers explore neuro-psychological mechanisms behind existential threats

A group of Salzburg-based researchers led by the psychologist Eva Jonas investigates the neuro-psychological mechanisms behind existential threats. What exactly happens in the process between threat and defensive reaction is at the center of an ongoing study funded by the Austrian Science Fund FWF.

12 Dec 2017

UVA researchers developing tool to help prostate cancer patients weigh treatment options

Researchers at the University of Virginia Cancer Center are developing a tool to help patients with prostate cancer better understand the potential risks and rewards of their treatment options.

8 Dec 2017

High risk of burnout, depression, and low quality of life found among health care workers

The current financial crisis has heavily impacted the public sector in Europe and, to a greater extent, in countries in which the public system has higher costs.

7 Dec 2017

New intelligence tool provides clarity to scientists in booming immuno-oncology field

Hanson Wade, the London-based life sciences knowledge services specialist, has launched IO Combination Trials Intelligence (www.beacon-intelligence.com), to provide clarity to scientists and strategists in the booming immuno-oncology combination field of study.

23 Nov 2017

UVA researchers developing new tool to help cancer patients make complex care decisions

Researchers at the University of Virginia Cancer Center are developing a tool to help patients with prostate cancer better understand the potential risks and rewards of their treatment options. And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information.

23 Nov 2017

Displaced Puerto Ricans face obstacles getting health care

The federal government has granted people affected by the devastating hurricanes that wracked coastal states and Puerto Rico 15 extra days to sign up for health coverage under the Affordable Care Act.

21 Nov 2017

New eDNA tool helps identify invasive clams before they become a problem

When seeking a cure for a disease, early detection is often the key. The same is true for eliminating invasive species. Identifying their presence in a lake before they are abundant is vital. A recent University of Illinois study successfully used environmental DNA to detect invasive clams in California and Nevada lakes. Researchers believe this tool can help identify pests before they become a problem.

17 Nov 2017

Scientists improve resolution of optical microscope using mirrored coverslip and computer algorithms

Researchers from the National Institutes of Health and the University of Chicago improved the speed, resolution, and light efficiency of an optical microscope by switching from a conventional glass coverslip to a reflective, mirrored coverslip and applying new computer algorithms to process the resulting data.

13 Nov 2017

Pre-menopausal women with advanced breast cancer unnecessarily excluded from clinical trials

Pre-menopausal women with the most common type of advanced breast cancer are usually excluded from medical research unnecessarily, according to an expert panel at the Advanced Breast Cancer Fourth International Consensus Conference.

6 Nov 2017

Climate change makes it difficult for sun’s UV rays to kill pathogens

Increasing organic runoff as a result of climate change may be reducing the penetration of pathogen-killing ultraviolet (UV) sunlight in inland lakes, rivers, and coastal waters, according to a new study in the journal Scientific Reports.

2 Nov 2017

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

New research from North Carolina State University reveals that prenatal exposure to bisphenol A (BPA) at levels below those currently considered safe for humans affects gene expression related to sexual differentiation and neurodevelopment in the developing rat brain.

31 Oct 2017

Cochrane review provides clarity about safety of mefloquine for preventing malaria in travelers

Researchers from LSTM Cochrane Infectious Diseases Group publish two systematic reviews this week about the safety of mefloquine (Lariam) for preventing malaria in travelers.

30 Oct 2017

BMS survey reveals negative effects of menopause on most aspects of women’s lives

Three quarters of women say that the menopause caused them to change their life and over half say it had a negative impact on their lives. Those are the headlines from a recent survey conducted by the British Menopause Society, released today to mark World Menopause Day.

19 Oct 2017

Researchers use powerful X-ray beams for ‘navigational map view’ of mouse brain

If brain imaging could be compared to Google Earth, neuroscientists would already have a pretty good "satellite view" of the brain, and a great "street view" of neuron details.

17 Oct 2017

AGS continues to offer support to bipartisan collaboration for better health system

Presidential action to alter current law risks undermining progress made by Congress, the American people, and a cadre of healthcare stakeholders to improve care access, care quality, and care costs for us all as we age, so say experts at the American Geriatrics Society evaluating recent orders by the Trump Administration.

13 Oct 2017

Researchers examine wide range of visual impairments developed by stroke survivors

A new University of Liverpool study, published today in Brain and Behaviour, examines the wide range of visual impairments developed by stroke survivors.

11 Oct 2017

CLARITY News and Research

Further Reading

Terrifying brush with death drives doctor to fight for patients

PENTAX Medical launches new, FDA-cleared C.A.P. HD Duodenoscope in the U.S.

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

Many breast cancer patients do not feel fully informed about their treatment options, say researchers

Researchers explore neuro-psychological mechanisms behind existential threats

UVA researchers developing tool to help prostate cancer patients weigh treatment options

High risk of burnout, depression, and low quality of life found among health care workers

New intelligence tool provides clarity to scientists in booming immuno-oncology field

UVA researchers developing new tool to help cancer patients make complex care decisions

Displaced Puerto Ricans face obstacles getting health care

New eDNA tool helps identify invasive clams before they become a problem

Scientists improve resolution of optical microscope using mirrored coverslip and computer algorithms

Pre-menopausal women with advanced breast cancer unnecessarily excluded from clinical trials

Climate change makes it difficult for sun’s UV rays to kill pathogens

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

Cochrane review provides clarity about safety of mefloquine for preventing malaria in travelers

BMS survey reveals negative effects of menopause on most aspects of women’s lives

Researchers use powerful X-ray beams for ‘navigational map view’ of mouse brain

AGS continues to offer support to bipartisan collaboration for better health system

Researchers examine wide range of visual impairments developed by stroke survivors

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology