Genetic Engineering News and Research

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Research reveals important mechanism in the repair of DNA double-strand breaks

Scientists have revealed an important mechanism in the repair of DNA double-strand breaks, according to new research published today in eLife.

24 Mar 2020

Using cannabinoids for management of acute pain

A new systematic review and meta-analysis showed a small but significant reduction in subjective pain scores for cannabinoid treatment compared to placebo in patients experiencing acute pain.

23 Mar 2020

Strategies for allocating stockpiled ventilators to healthcare facilities during a pandemic

Key factors must be taken into account in determining the need for and allocation of scarce ventilators during a severe pandemic, especially one causing respiratory illness.

22 Mar 2020

Genetically modified neurons could enhance function of clinical implants

A team has genetically reprogrammed neurons that could enhance electrical implant function used in various clinical scenarios.

20 Mar 2020

Researchers produce fat busting proteins in the lab

Triglycerides, those fats that seem to be the bane of any diet, remain a mystery for many researchers. Plenty of them are in Big Macs, deep pan pizza and the like, but some are a necessity to fuel the body for daily activities.

19 Mar 2020

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team led by researchers at the RIKEN Cluster for Pioneering Research have identified a key player and the molecular events underlying this phenomenon in mice.

19 Mar 2020

High-throughput screening of AAV vector capsid libraries reveals unexpected insights

Researchers have used high-throughput screening of adeno-associated viral (AAV) vector capsid libraries to maximize the likelihood of obtaining AAV variants with desired properties.

18 Mar 2020

Novel Alzheimer's risk genes affect microglial response to amyloid-beta

Our DNA determines a large part of our risk for Alzheimer's disease, but it remained unclear how many genetic risk factors contribute to disease.

18 Mar 2020

MCL1 protein essential in protecting the intestine against cancer development

An international team of researchers from the University of Zurich, the University Hospital Zurich, Heidelberg and Glasgow has identified a novel function for the cell death regulating protein MCL1: It is essential in protecting the intestine against cancer development – independent of bacterial-driven inflammation.

18 Mar 2020

COVID-19 epidemic is the product of natural evolution, study finds

The novel SARS-CoV-2 coronavirus that emerged in the city of Wuhan, China, last year and has since caused a large scale COVID-19 epidemic and spread to more than 70 other countries is the product of natural evolution, according to findings published today in the journal Nature Medicine.

17 Mar 2020

Uncovering the Achilles' heel of cancer cells to find effective cures

The key to effective cures for cancers is to find weak points of cancer cells that are not found in non-cancer cells.

17 Mar 2020

Anesthesia standards for coronavirus-infected patients requiring emergency surgery

Physicians describe the standardized procedure of surgical anesthesia for patients with COVID-19 infection requiring emergency surgery to minimize the risk of virus spread and reduce lung injury in a Letter to the Editor published in Surgical Infections, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

16 Mar 2020

Study examines e-cigarette use by women during preconception and/or pregnancy

A new study of 1,365 racially/ethnically diverse, low-income pregnant women found that 4% reported e-cigarette use.

16 Mar 2020

Researchers uncover clues to how statins kill cancer cells

More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.

12 Mar 2020

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Based on proof-of-concept results from clinical trials at University of North Carolina Lineberger Comprehensive Cancer Center and Baylor College of Medicine, an investigational cellular immunotherapy for Hodgkin lymphoma has received a Regenerative Medicine Advanced Therapy designation from the U.S. Food and Drug Administration.

9 Mar 2020

Respiratory antivirals and risk to breastfeeding women

Little data is available about the ability of antiviral drugs used to treat COVID-19, coronavirus, to enter breastmilk, let alone the potential adverse effects on breastfeeding infants.

4 Mar 2020

Molecule found in oranges could reduce obesity and reverse its negative side-effects

The equivalent of just two and a half glasses of orange juice a day could reverse obesity and reduce the risk of heart disease and diabetes.

3 Mar 2020

Study identifies a protein and signaling pathway that may contribute to sudden cardiac death

By studying the sick hearts removed from four patients undergoing heart transplants, researchers have identified a protein and a signaling pathway that may contribute to sudden death in an inherited form of heart disease.

3 Mar 2020

Challenges for translating pharmacomicrobiomics to personalized medicine

A new Commentary identifies three actionable challenges for translating pharmacomicrobiomics to personalized medicine in 2020.

2 Mar 2020

Study reveals the neural basis of sensory hypersensitivity in people with autism

Many people with autism spectrum disorders are highly sensitive to light, noise, and other sensory input. A new study in mice reveals a neural circuit that appears to underlie this hypersensitivity, offering a possible strategy for developing new treatments.

2 Mar 2020

Genetic Engineering News and Research

Research reveals important mechanism in the repair of DNA double-strand breaks

Using cannabinoids for management of acute pain

Strategies for allocating stockpiled ventilators to healthcare facilities during a pandemic

Genetically modified neurons could enhance function of clinical implants

Researchers produce fat busting proteins in the lab

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

High-throughput screening of AAV vector capsid libraries reveals unexpected insights

Novel Alzheimer's risk genes affect microglial response to amyloid-beta

MCL1 protein essential in protecting the intestine against cancer development

COVID-19 epidemic is the product of natural evolution, study finds

Uncovering the Achilles' heel of cancer cells to find effective cures

Anesthesia standards for coronavirus-infected patients requiring emergency surgery

Study examines e-cigarette use by women during preconception and/or pregnancy

Researchers uncover clues to how statins kill cancer cells

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Respiratory antivirals and risk to breastfeeding women

Molecule found in oranges could reduce obesity and reverse its negative side-effects

Study identifies a protein and signaling pathway that may contribute to sudden cardiac death

Challenges for translating pharmacomicrobiomics to personalized medicine

Study reveals the neural basis of sensory hypersensitivity in people with autism

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo