Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Smart Cells launches social campaign to support Rare Disease Day 2018

There are more than 6000 known rare diseases and over 30 million people living daily with them. 28th February marks Rare Disease Day 2018, a date that highlights awareness around these conditions and the need for more research into them.

From Smart Cells International Ltd 23 Feb 2018

Scientists discover the genetic cause of immune disorders

Scientists from the Cincinnati Children’s have successfully identified a gene mutation that affects T cell function and promotes immune disorders.

1 Feb 2018

Persistent immune activation may contribute to increased risk of CVD in people with HIV

A review of more than 80 studies reveals that changes in the immune cells of people with human immunodeficiency virus (HIV) infection may increase their risk of cardiovascular disease (CVD). The review is published in the journal Physiology.

24 Jan 2018

Malnutrition remains underdiagnosed, undertreated for decades among hospitalized patients

Malnutrition among hospitalized patients remains a serious issue that has been underdiagnosed and undertreated for decades.

9 Jan 2018

A guide to Severe Combined Immunodeficiency Disease, review released

A new review published today in the Canadian Medical Association Journal provides guidance on Severe Combined Immunodeficiency Disease (SCID), a deadly and rare disease that is potentially curable if detected early.

18 Dec 2017

New review provides guidance to doctors who may treat infants with ‘bubble boy disease’

A new review provides guidance on a deadly, but rare, disease that is potentially curable if identified early. Severe combined immunodeficiency disease (SCID), known as the "bubble boy disease" in the 1970s, is treatable with a stem cell transplant, gene therapy and other treatments if identified at birth or soon after.

18 Dec 2017

Chemical found in marijuana could help HIV patients maintain their mental function

A chemical found in marijuana, known as tetrahydrocannabinol, or THC, has been found to potentially slow the process in which mental decline can occur in up to 50 percent of HIV patients, says a new Michigan State University study.

12 Dec 2017

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

Although combination antiretroviral therapy (cART) has improved survival of patients infected with HIV and has reduced the incidence of severe neurologic complications, almost half of cART-treated HIV patients experience some degree of neurocognitive impairment (neuroHIV).

8 Dec 2017

BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Rahm Gummuluru, PhD, associate professor of microbiology at Boston University School of Medicine, and Bjoern Reinhard, PhD, professor of chemistry at Boston University, have been awarded a Research Project Grant from the National Institutes of Allergy and Infectious Diseases/National Institute of Health.

5 Dec 2017

Desperate for coverage: Are short-term plans better than none at all?

When one of Cindy Holtzman's clients told the Woodstock, Ga., broker he was considering dropping his Affordable Care Act plan because next year's cost approached $23,000 for his family of four, she suggested a new option: a back-to-back set of four, 90-day short-term plans, which would effectively give them a modicum of medical coverage for 2018.

1 Dec 2017

Orchard Therapeutics opens new facility for technical operations in San Francisco Bay area

Orchard Therapeutics, a clinical-stage biotechnology company dedicated to transforming the lives of patients with rare disorders through innovative gene therapies, today announced the opening of a second facility for technical operations in the San Francisco Bay Area.

1 Dec 2017

HIV directly impacts the brain in early stages of infection

Stellenbosch University researchers have discovered that the human immunodeficiency virus (HIV) directly impacts the brain in the early stages of the infection.

30 Nov 2017

Study highlights need to improve quality of cardiovascular care for HIV-positive adults

People with both HIV and risk factors for heart disease and stroke were less likely to be treated with cholesterol-lowering statin drugs and aspirin than patients without HIV. The researchers believe this to be the first national study comparing statin use in patients with and without HIV and the first extensive analysis using U.S. data.

23 Nov 2017

Researchers test new vaccination strategy against HIV-related SIV in monkeys

According to the WHO, there are currently more than 36 million people infected with the human immunodeficiency virus (HIV) and a further 2.4 million become infected every year.

15 Nov 2017

Monoclonal antibody effectively blocks development of graft-versus-host disease, research shows

Newly published research provides preclinical proof-of-concept for the ability of PRO 140, a humanized anti-CCR5 monoclonal antibody under development by CytoDyn Inc., to effectively block the development of graft-versus-host disease (GvHD), a potentially lethal complication of bone marrow stem cell (BMSC) transplantation.

14 Nov 2017

Researchers shed light on link between cholera outbreaks affecting African and American continents

Researchers at the Institut Pasteur and the Wellcome Trust Sanger Institute, in collaboration with several other international institutions, recently published two studies tracing the history of cholera outbreaks in Africa, Latin America and the Caribbean from the last 60 years.

13 Nov 2017

Immunodeficiency News and Research

Further Reading

Smart Cells launches social campaign to support Rare Disease Day 2018

Scientists discover the genetic cause of immune disorders

Persistent immune activation may contribute to increased risk of CVD in people with HIV

Malnutrition remains underdiagnosed, undertreated for decades among hospitalized patients

A guide to Severe Combined Immunodeficiency Disease, review released

New review provides guidance to doctors who may treat infants with ‘bubble boy disease’

Chemical found in marijuana could help HIV patients maintain their mental function

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Desperate for coverage: Are short-term plans better than none at all?

Orchard Therapeutics opens new facility for technical operations in San Francisco Bay area

HIV directly impacts the brain in early stages of infection

Study highlights need to improve quality of cardiovascular care for HIV-positive adults

Researchers test new vaccination strategy against HIV-related SIV in monkeys

Monoclonal antibody effectively blocks development of graft-versus-host disease, research shows

Researchers shed light on link between cholera outbreaks affecting African and American continents

McMaster study: High-risk sexual behavior among women may increase risk of acquiring STIs

4-in-1 influenza vaccine appears to provide broad protection against flu

World’s only Atomo HIV Self Test receives CE Marking from European Union Notified Body

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