Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

University of Bonn researchers find how cells in the body can detect genetic material of retroviruses

Researchers at the University of Bonn have discovered how cells in the body can detect the genetic material of so-called retroviruses. The pathogen of the immunodeficiency disease AIDS, the HI-1 virus, also belongs to this group. At the same time, the HI virus appears to circumvent this important defense mechanism.

8 Sep 2015

Only one in five gay and bisexual teen boys tested for HIV

Young men who have sex with men have the highest risk for HIV infection, but only one in five has ever been tested for HIV, a much lower rate than testing for non-adolescents, reports a new national Northwestern Medicine study conducted in partnership with the Center for Innovative Public Health Research.

26 Aug 2015

Reducing amyloid fibril levels in semen may help reduce transmission of HIV

There may be two new ways to fight AIDS -- using a heat shock protein or a small molecule - to attack fibrils in semen associated with the human immunodeficiency virus (HIV) during the initial phases of infection, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

18 Aug 2015

UTHealth's Kayo Fujimoto awarded grant to study genetic and social aspects of HIV transmission

Kayo Fujimoto, Ph.D., assistant professor in the Center for Health Promotion and Prevention Research at The University of Texas Health Science Center at Houston School of Public Health, has been awarded a grant to study the genetic and social network aspects of human immunodeficiency virus (HIV) transmission.

24 Jul 2015

Researchers report new drug combination that effectively treats HCV patients co-infected with HIV

Roughly 20 to 30 percent of patients with hepatitis C virus (HCV) are also infected with human immunodeficiency virus type 1 (HIV). Both blood-borne viruses share the same modes of transmission, but many HCV medications currently have significant limitations due to adverse interactions with HIV treatments. Researchers at University of California, San Diego School of Medicine report a new combination that effectively treats HCV in patients co-infected with HIV.

22 Jul 2015

New research identifies potential treatment for primary effusion lymphoma

New research from the University of Southern California Norris Comprehensive Cancer Center has identified a potential treatment for a rare but previously incurable form of lymphoma that is observed primarily in patients with HIV/AIDS infection.

8 Jul 2015

Bidding for Health charity auction to raise funds in support of Immunodeficiency Canada

Bidding for Health charity auction will raise much needed funds in support of a Canadian national registered charity Immunodeficiency Canada. 100% of proceeds raised will be used towards its programs and services. There is a wide range of exciting items to bid on with new items added throughout the month, so check back often. Something for all ages.

3 Jul 2015

New IDF ePHR app launched to help people living with primary immunodeficiency manage their health

The Immune Deficiency Foundation has announced the launch of a mobile app for IDF ePHR, the electronic health record specifically designed for the primary immunodeficiency (PI) community. IDF ePHR allows individuals and caregivers living with PI to track important health information, including medications, diagnoses, symptoms, infections, and other critical data.

2 Jul 2015

HIV capsid protein plays crucial role in the virus' life cycle

HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges for researchers. Now, scientists at the University of Missouri are gaining a clearer idea of what a key protein in HIV looks like, which will help explain its vital role in the virus' life cycle.

2 Jul 2015

International researchers identify previously unknown genetic immunodeficiency

An analysis of five families has revealed a previously unknown genetic immunodeficiency, says an international team led by researchers from Boston Children's Hospital. The condition, linked to mutations in a gene called DOCK2, deactivates many features of the immune system and leaves affected children open to a unique pattern of aggressive, potentially fatal infections early in life.

19 Jun 2015

Single difference in HIV's genetic code influences progression of disease

In a finding that furthers the understanding of human immunodeficiency virus (HIV), researchers from Children's Hospital Los Angeles discovered two locations where a single difference in HIV's genetic code altered the way the virus infected the cell, thereby influencing the progression of the disease.

18 Jun 2015

IDIBELL and IDIPAZ scientists identify epigenetic alterations in CVID

Researchers of the Chromatin and Disease Group from the Bellvitge Biomedical Research Institute and La Paz Hospital have identified epigenetic alterations in Common Variable Immunodeficiency (CVID), the most common primary immunodeficiency, using as a starting point genetically identical monozygotic twins discordant for the disease.

18 Jun 2015

NIH-funded study identifies DOCK2 deficiency

Researchers funded by the National Institutes of Health have identified a new immune disorder--DOCK2 deficiency--named after the mutated gene responsible for the disease.

18 Jun 2015

Beckman Coulter brings new thinking to new lab challenges at EuroMedLab 2015

Beckman Coulter Diagnostics supports IFCC-EFLM EuroMedLab 2015 with a showcase of solutions to improve workflow for the diagnostics laboratory. Held from 22-24 June 2015 at the Paris Palais des Congrès France, the company demonstrates its dedication to moving the clinical diagnostic lab forward with its total laboratory solution—from automation, chemistry, immunoassay and haematology to microbiology and its new molecular diagnostics system.

From Beckman Coulter Diagnostics 18 Jun 2015

Chemical drug safely controls side effects associated with haploidentical stem cell transplantation

Researchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Houston Methodist and Texas Children's Hospital have found that a single dose of an otherwise harmless drug can safely control the severe and often lethal side effects associated with haploidentical stem cell transplantation.

15 May 2015

ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

ViiV Healthcare today announced the start of a Phase III clinical trial programme to evaluate the safety and efficacy of dolutegravir (Tivicay) and rilpivirine (Edurant) as maintenance therapy for adult patients with HIV.

6 May 2015

AIDS patients at increased risk of developing intermediate-stage AMD

Patients with acquired immunodeficiency syndrome (AIDS) have a four-fold increase in their risk of developing intermediate-stage age-related macular degeneration (AMD) compared to people of the same age who are not infected with HIV, according to results from the Longitudinal Study of the Ocular Complications of AIDS (LSOCA) presented today at the 2015 ARVO Annual Meeting in Denver, CO.

5 May 2015

Chickenpox virus can cause strokes in patients with compromised immune systems

Patients infected with human immunodeficiency virus (HIV) can, in rare cases, experience bleeding on the brain that causes a type of stroke called intracerebral hemorrhage.

5 May 2015

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

Scientists at Texas Biomedical Research Institute have begun work on a nearly $3.4 million study funded by the National Institutes of Health over the next four years to create an attenuated, or weakened, virus that is a hybrid of the papilloma virus and the human immunodeficiency virus, with the potential to jumpstart a body's immune response to develop antibodies against both viruses.

30 Apr 2015

Scientists identify missing genetic link in common variable immunodeficiency disorder

In the largest genetic study to date of a challenging immunodeficiency disorder, scientists have identified a gene that may be a "missing link" between overactive and underactive immune activity. The gene candidate also plays a key role in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and allergies.

23 Apr 2015

Immunodeficiency News and Research

Further Reading

University of Bonn researchers find how cells in the body can detect genetic material of retroviruses

Only one in five gay and bisexual teen boys tested for HIV

Reducing amyloid fibril levels in semen may help reduce transmission of HIV

UTHealth's Kayo Fujimoto awarded grant to study genetic and social aspects of HIV transmission

Researchers report new drug combination that effectively treats HCV patients co-infected with HIV

New research identifies potential treatment for primary effusion lymphoma

Bidding for Health charity auction to raise funds in support of Immunodeficiency Canada

New IDF ePHR app launched to help people living with primary immunodeficiency manage their health

HIV capsid protein plays crucial role in the virus' life cycle

International researchers identify previously unknown genetic immunodeficiency

Single difference in HIV's genetic code influences progression of disease

IDIBELL and IDIPAZ scientists identify epigenetic alterations in CVID

NIH-funded study identifies DOCK2 deficiency

Beckman Coulter brings new thinking to new lab challenges at EuroMedLab 2015

Chemical drug safely controls side effects associated with haploidentical stem cell transplantation

ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

AIDS patients at increased risk of developing intermediate-stage AMD

Chickenpox virus can cause strokes in patients with compromised immune systems

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

Scientists identify missing genetic link in common variable immunodeficiency disorder

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