In Utero News and Research

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Sequenom and Lenetix to develop Rhesus D prenatal diagnostic

Sequenom, Inc. and Lenetix Medical Screening Laboratory, Inc., a provider of rapid genetic screening and diagnostic testing for clinicians worldwide, today announced that they have entered into a collaboration and license agreement to develop and commercialize a proprietary non-invasive prenatal Rhesus D (RhD) incompatibility test based on Sequenom patent rights and RT PCR methodology.

29 Jan 2007

Drinking during pregnancy linked to offspring's risk of alcohol disorders in early adulthood

Individuals whose mothers drink three or more glasses of alcohol at any one occasion in early pregnancy have an increased risk of developing alcohol disorders by 21 years of age, according to a report in the September issue of Archives of General Psychiatry.

4 Sep 2006

Research illustrates BAG3 protein's importance in maintaining mature skeletal muscle

Muscle cells that should grow stronger with use instead self-destruct when a protein called BAG3 isn't around, researchers have shown.

30 Aug 2006

Long-term effects of in utero influenza exposure in the post-1940 U.S. population

While much attention has been paid to how inherited traits such as skin tone or height influence economic success, a groundbreaking new study from the Journal of Political Economy argues that it is a malleable characteristic - in utero health - that most strongly indicates how well a child will fare in adulthood.

7 Aug 2006

Diethylstilbestrol-exposed women at greater risk of developing breast cancer

So-called "DES daughters," born to mothers who used the anti-miscarriage drug diethylstilbestrol during pregnancy, are at a substantially greater risk of developing breast cancer compared to women who were not exposed to the drug in utero.

7 Aug 2006

Comprehensive care for complex, high-risk pregnancies

As many as 3 percent of all pregnancies result in the birth of a baby with chromosomal anomalies like Down syndrome or structural anomalies such as congenital heart disease.

23 May 2006

Active ingredient in soy may explain why Asians have lower rates of obesity and cancer

A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center.

13 Apr 2006

Exposure to arsenic in utero and early childhood tied to lung disease and cancer in adults

Children who are exposed to high levels of arsenic in their drinking water are seven to 12 times more likely to die of lung cancer and other lung diseases in young adulthood, a new study by University of California, Berkeley, and Chilean researchers suggests.

11 Apr 2006

Increase in Vitamin E tied to fewer in utero deaths

Manipulating the in utero environment may alter the onset of cancers that appear later in the lives of mammals, according to a new University of Toronto study published in the journal Carcinogenesis.

23 Mar 2006

Pregnancy complications increase risk of heart disease

Young women who have a range of complications during pregnancy, including preeclampsia, gestational diabetes or preterm birth, are at an increased risk of developing heart disease and of dying later in life

14 Mar 2006

Effects of prenatal exposure to pesticides

Children in Ecuador whose mothers were exposed to pesticides while pregnant had increased blood pressure and diminished ability to copy geometric figures as compared to a control group, according to an epidemiological study in the March issue of Pediatrics.

9 Mar 2006

Causes of type 1 diabetes

Scientists are casting a wide, tightly woven net with the goal of catching the causes of type 1 diabetes.

16 Feb 2006

Use of antidepressants during pregnancy linked to neonatal abstinence syndrome in infants

Almost one-third of 60 newborn infants whose mothers took antidepressants during pregnancy experienced neonatal abstinence syndrome, a type of withdrawal with symptoms that include high-pitched crying, tremors and disturbed sleep, according to a study in the February issue of Archives of Pediatrics & Adolescent Medicine.

9 Feb 2006

Stress in pregnancy means boys will be stronger

A team from the University of California, Berkeley, have found in a study that pregnant women are more likely to miscarry male fetuses than females fetuses during times of stress.

25 Jan 2006

Cloned stem cells are perfectly normal

Scientists generally agree that all cloned animals are biologically flawed. But they don't agree about what that means for stem cells derived from cloned embryos, the basis for therapeutic cloning.

18 Jan 2006

Brains of babies born very prematurely do not develop as well as those who are carried to full-term

"We found that in very premature babies, a part of the brain doesn't show normal growth after birth, and in fact some parts of the brain didn't change at all from the day the babies were born until they reached what would have been a full-term birth date."

20 Nov 2005

Breastfeeding does not raise the risk of mother-to-child transmission of hepatitis C virus

One study found that infant girls are twice as likely to be infected as infant boys. Both studies provide new information with which to counsel pregnant women infected with HCV. Taken together, the two new studies expand upon preliminary data from smaller studies of mother-to-child transmission of HCV.

1 Nov 2005

Comparison of the risks and benefits of fish consumption

A comparison of the risks and benefits of fish consumption suggests that government advisories warning women of childbearing age about mercury exposure should be issued with caution.

19 Oct 2005

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005

Key neural system at risk from prenatal exposure to alcohol

In a study of adult monkeys who were exposed to moderate amounts of alcohol in utero, scientists have found that prenatal exposure to alcohol - even in small doses - has pronounced effects on the development and function later in life of the brain's dopamine system, a critical component of the central nervous system that regulates many regions of the brain.

21 Sep 2005