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Young inflammatory bowel disease patients have low bone mass

Children and adolescents with inflammatory bowel disease have significantly lower bone mineral density than their healthy peers, even after adjusting for pubertal delay, Finnish researchers report.

28 Jun 2012

Genetic risk for schizophrenia linked to brain volume alterations

Patients with schizophrenia and their unaffected first-degree relatives show altered gray and white matter volumes in specific brain regions compared with mentally healthy individuals, researchers report.

26 Jun 2012

$Vertebral fractures flag vascular disease risk$

Vertebral fractures flag vascular disease risk

Abdominal aortic calcification in elderly men appears to be associated with vertebral fractures, say Moroccan scientists.

19 Jun 2012

Common sparrow and Tyrannosaurus Rex are more closely related than believed

At first glance, it's hard to see how a common house sparrow and a Tyrannosaurus Rex might have anything in common. After all, one is a bird that weighs less than an ounce, and the other is a dinosaur that was the size of a school bus and tipped the scales at more than eight tons.

28 May 2012

VEN occurs also in the insula of macaque monkeys

The anterior insular cortex is a small brain region that plays a crucial role in human self-awareness and in related neuropsychiatric disorders. A unique cell type - the von Economo neuron (VEN) - is located there. For a long time, the VEN was assumed to be unique to humans, great apes, whales and elephants.

22 May 2012

Panobinostat able to target and destroy triple negative breast cancer

The histone de-acetylase (HDAC) inhibitor panobinostat is able to target and destroy triple negative breast cancer, reveals a new study published in BioMed Central's open access journal Breast Cancer Research.

21 May 2012

Linkam Scientific temperature controlled warm stages chosen for sperm motility in human fertility testing

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments, have been chosen by an NHS Fertility clinic as suppliers of a controlled warm stage to perform routine semen analysis at body temperature.

From Linkam Scientific Instruments 16 May 2012

Study demonstrates accuracy of AliveCor’s iPhone-based ECG

AliveCor, the developer of a breakthrough mobile electrocardiogram (ECG) recorder, today announced results from a study that demonstrated the accuracy of the company's iPhone-based device, by comparing its Lead I to Lead I from a conventional 12-lead ECG. The study found that the iPhone-based event recorder is an accurate clinical tool for ECG assessment and could prove to be a new tool for allowing immediate recording and analysis of an ECG rhythm.

From AliveCor, Inc. 14 May 2012

Study shows effects of psychotropic drug treatment on brain morphology

It is increasingly recognized that chronic psychotropic drug treatment may lead to structural remodeling of the brain. Indeed, clinical studies in humans present an intriguing picture: antipsychotics, used for the treatment of schizophrenia and psychosis, may contribute to cortical gray matter loss in patients, whereas lithium, used for the treatment of bipolar disorder and mania, may preserve gray matter in patients.

9 May 2012

Positive results from Repligen's RG3039 Phase 1 study for spinal muscular atrophy

Repligen Corporation today announced positive results from a Phase 1 study to evaluate the pharmacokinetic (PK) and safety profile of RG3039, a novel small molecule drug candidate for the potential treatment of spinal muscular atrophy (SMA).

25 Apr 2012

Novel system for 3D reconstruction and examination of tissues at microscopic resolution

Researchers have developed a novel, easy-to-use system for three-dimensional (3D) reconstruction and examination of tissues at microscopic resolution, with the potential to significantly enhance the study of normal and disease processes, particularly those involving structural changes. The new approach, using conventional histopathological methods, is described in the May issue of The American Journal of Pathology.

17 Apr 2012

New compound reverses major symptoms associated with FXS

A recent study finds that a new compound reverses many of the major symptoms associated with Fragile X syndrome (FXS), the most common form of inherited intellectual disability and a leading cause of autism. The paper, published by Cell Press in the April 12 issue of the journal Neuron, describes the exciting observation that the FXS correction can occur in adult mice, after the symptoms of the condition have already been established.

12 Apr 2012

Elective endovascular aneurysm repair benefits men more than women

A study published in the April issue of Journal of Vascular Surgery reports that women derive less benefit than men from elective endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAA's). The research was done at The Vascular Group, The Institute for Vascular Health and Disease, Albany Medical College, The Center for Vascular Awareness Inc., in Albany, NY.

31 Mar 2012

Starvation during childhood may increase risk of heart complications

Russians born during the Leningrad Siege in World War II, which was responsible for some of the greatest losses of civilian life in history, are giving scientists new strategies to identify people who experienced intrauterine growth restriction (IUGR) and starvation during childhood at greatest risk of developing long term heart complications.

31 Mar 2012

EU's Safety Evaluation Ultimately Replacing Animal Testing initiative tests Roche's xCELLigence system

Roche's xCELLigence RTCA System is being used in the European Union's SEURAT (Safety Evaluation Ultimately Replacing Animal Testing) initiative to run five years from 2011 to 2016.

From Roche Sequencing and Life Science 29 Mar 2012

DBS introduces novel Multiplex Immunohistochemistry cancer kits

Diagnostic Biosystems, a specialty Immunohistochemistry company, announces its debut as an automated IHC company, introducing the Mosaic 360 System with a product offering of novel Multiplex Immunohistochemistry kits and a complementary line of optimized IHC reagents.

19 Mar 2012

Biomedical Systems launches wireless ambulatory ECG monitoring system for management of AF

Biomedical Systems, a global provider of cardiac diagnostic services and products, has introduced the TruVue® Wireless Ambulatory ECG Monitoring System for the diagnosis and management of atrial fibrillation and other complex cardiac arrhythmia.

19 Mar 2012

PCP signaling restricts neural growth during regeneration, homeostasis and development

The genetic pathway that regulates the way cells align themselves relative to each other has been found to act as a "stop sign" that signals organisms when to halt cell growth, according to new research published by biologists at the Center for Regenerative and Developmental Biology in Tufts University's School of Arts and Sciences.

16 Mar 2012

Scientists develop realistic model to explain cellular signal processing

Scientists at the Charité - Universitätsmedizin Berlin and the US National Institutes of Health (NIH) have developed a realistic model for explaining cellular signal processing.

13 Mar 2012

Researchers refute widely accepted hypothesis about causative step in ALS

In science, refuting a hypothesis can be as significant as proving one, all the more so in research aimed at elucidating how diseases proceed with a view toward preventing, treating, or curing them. Such a discovery can save scientists from spending precious years of effort exploring a dead end. In a study published in the Proceedings of the National Academy of Sciences, Munich-based researchers refute a widely accepted hypothesis about a causative step in neurodegenerative conditions.

1 Mar 2012