OCT News and Research

RSS

Smoking and sex found to shape early cellular changes linked to bladder cancer

Bladder cancer is one of the most common cancers worldwide. Men are around four times more likely to develop it than women, and smoking is the main known environmental risk factor.

8 Oct 2025

New brain circuit discovery offers hope for chronic pain relief

Acute or short-lived pain, despite its bad reputation, is usually a lifesaver. It acts as a transient negative sensory experience that helps us avoid danger.

8 Oct 2025

Inappropriate triage prolongs time to pain medication in vaso-occlusive crisis

Most individuals living with sickle cell disease who presented to the emergency department with a pain crisis, known as vaso-occlusive crisis (VOC), were not triaged appropriately according to established national guidelines, reveals a study published today in Blood Advances.

8 Oct 2025

Survey finds widespread gaps in safe tissue containment during laparoscopic gynecologic surgery

A new national survey of first-year fellows in minimally invasive gynecologic surgery (FMIGS) has revealed significant gaps in the use of FDA-cleared containment systems during laparoscopic hysterectomy and myomectomy.

8 Oct 2025

Largest study of African American brain tissue reveals key Alzheimer gene activity

The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry (EA) individuals living in the U.S.

8 Oct 2025

Engineered Salmonella therapy delivers immune payloads to combat cancer

A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."

8 Oct 2025

New dual-target vaccine shows promise against typhoid and Salmonella

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella--two major causes of illness and death among children in sub-Saharan Africa.

8 Oct 2025

Engineered CAR-NK cells show enhanced cancer killing and immune evasion

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

8 Oct 2025

Improved five-year cancer survival observed after Medicaid expansion

Adoption of Medicaid expansion in U.S. states appeared to improve both five-year cause-specific and overall survival in cancer patients.

8 Oct 2025

California’s nursing shortage is getting worse. Front-line workers blame management.

California, like much of the nation, is not producing enough nurses working at bedsides to meet the needs of an aging and diverse population, fueling a workforce crunch that risks endangering quality patient care.

8 Oct 2025

Calorie labeling in England linked to only small reductions in out-of-home food

Calorie labeling, which became law in April 2022 in England, is associated with only a small (2%) average reduction in the energy content of food that is available away from home, finds research published in the open access journal BMJ Public Health.

7 Oct 2025

UCSF and Allen Institute create most detailed data-driven map of the mouse brain

In a powerful fusion of AI and neuroscience, researchers at the University of California, San Francisco (UCSF) and Allen Institute designed an AI model that has created one of the most detailed maps of the mouse brain to date, featuring 1,300 regions/subregions.

7 Oct 2025

New computer-driven method helps understand how membrane proteins work at the atomic level

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring cells stick together.

7 Oct 2025

Exercise snacks may help improve heart and lung health in sedentary adults

Exercise snacks-intentional short bursts of physical activity-may be an effective way of boosting the cardiorespiratory fitness of physically inactive adults, finds a synthesis of the available research, published online in the British Journal of Sports Medicine.

7 Oct 2025

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

The strong opioid painkiller, tramadol, is not that effective at easing chronic pain for which it's widely prescribed, finds a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine.

7 Oct 2025

Cesarean births in advanced labor linked to higher risk of womb scarring

Women who have Cesarean births at an advanced stage of labor are about eight times more likely to develop scars in the womb which are known to increase the likelihood of premature births in future pregnancies, UCL researchers have found.

7 Oct 2025

Scientists develop a high accuracy blood test to diagnose Chronic Fatigue Syndrome

Scientists at the University of East Anglia and Oxford Biodynamics have developed a high accuracy blood test to diagnose Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (ME/CFS).

7 Oct 2025

Whole genome sequencing may guide care for thousands of breast cancer patients

Whole genome sequencing offered to breast cancer patients is likely to identify unique genetic features that could either guide immediate treatment or help match patients to clinical trials for over 15,000 women a year, say scientists at the University of Cambridge.

7 Oct 2025

Innovative approaches target PAR2 receptor to alleviate gut pain

Abdominal pain is a hallmark of many digestive disorders, including inflammatory bowel disease and irritable bowel syndrome.

7 Oct 2025

Protected areas of defined geographic zones may have unintended impacts on children’s diet

Protected areas of defined geographic zones can slow biodiversity loss and bolster conversation efforts, but they may have unintended impacts on the diets of children who live nearby, according to new research from scientists at Penn State.

7 Oct 2025

OCT News and Research

Smoking and sex found to shape early cellular changes linked to bladder cancer

New brain circuit discovery offers hope for chronic pain relief

Inappropriate triage prolongs time to pain medication in vaso-occlusive crisis

Survey finds widespread gaps in safe tissue containment during laparoscopic gynecologic surgery

Largest study of African American brain tissue reveals key Alzheimer gene activity

Engineered Salmonella therapy delivers immune payloads to combat cancer

New dual-target vaccine shows promise against typhoid and Salmonella

Engineered CAR-NK cells show enhanced cancer killing and immune evasion

Improved five-year cancer survival observed after Medicaid expansion

California’s nursing shortage is getting worse. Front-line workers blame management.

Calorie labeling in England linked to only small reductions in out-of-home food

UCSF and Allen Institute create most detailed data-driven map of the mouse brain

New computer-driven method helps understand how membrane proteins work at the atomic level

Exercise snacks may help improve heart and lung health in sedentary adults

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

Cesarean births in advanced labor linked to higher risk of womb scarring

Scientists develop a high accuracy blood test to diagnose Chronic Fatigue Syndrome

Whole genome sequencing may guide care for thousands of breast cancer patients

Innovative approaches target PAR2 receptor to alleviate gut pain

Protected areas of defined geographic zones may have unintended impacts on children’s diet

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News