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New molecular mechanism offers hope for treating depression in the elderly

Major depressive disorder (MDD) is one of the most common psychiatric illnesses worldwide, but its molecular causes have still not been clearly identified.

25 Aug 2025

Sugary drinks increase hair loss risk, scientists warn

A systematic review of 17 studies involving 61,332 participants reveals that vitamin D, iron, and certain foods and supplements play critical roles in hair health. Conversely, sugary drinks, alcohol, and excess vitamin A may worsen hair loss and hair quality.

25 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs).

22 Aug 2025

New 3D bioprinting method can customize protein-based emulsion gels for dysphagia diets

In rapidly aging societies like Japan, the simple act of swallowing meals can be challenging for many. This condition, known as dysphagia, affects millions of people worldwide and can significantly deteriorate a person's quality of life.

22 Aug 2025

Epstein-Barr virus protein enhances cancer gene activity in HPV-positive cervical cells

A new research paper was published in Volume 16 of Genes & Cancer on August 6, 2025, titled "Epstein-Barr virus nuclear antigen 1 upregulates Derlin1 and PSMD10 expression in HeLa cells."

22 Aug 2025

Study finds no increased risk of death associated with higher intake of animal protein

Eating animal-sourced protein foods is not linked to a higher risk of death and may even offer protective benefits against cancer-related mortality, new research finds.

22 Aug 2025

Hemoglobin emerges as a natural antioxidant defense in the brain

Did you know the same protein that gives blood its red color and carries oxygen throughout the body is also present inside brain cells? Hemoglobin, long celebrated for ferrying oxygen in red blood cells, has now been revealed to play an overlooked - and potentially game-changing - antioxidant role in the brain.

22 Aug 2025

Hypothalamic neurons help maintain blood sugar during daily activities

The brain controls the release of glucose in a wide range of stressful circumstances, including fasting and low blood sugar levels.

21 Aug 2025

Edible microbeads trap fat to support weight loss

Weight-loss interventions, including gastric bypass surgery and drugs that prevent dietary fat absorption, can be invasive or have negative side effects.

21 Aug 2025

Neuroscientists split on whether memories can be extracted from preserved brains

A new survey of 312 neuroscientists reveals strong support for synaptic connectivity as the basis of long-term memory, but deep divides remain over memory extraction and brain emulation feasibility. The findings highlight both emerging consensus and sharp uncertainty in how memories are physically stored.

21 Aug 2025

Can AI help you eat healthier?

Researchers developed and validated an AI-based nutrition recommendation system (AINR) that generates weekly Mediterranean meal plans tailored to individual needs and dietary restrictions. Tested on 4,000 simulated users, the system achieved high accuracy in calorie and nutrient targets but struggled with profiles involving milk and nut allergies.

21 Aug 2025

Research shows how lysosomes respond to stress

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

21 Aug 2025