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New type of CRISPR gene scissors discovered

Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.

4 Jan 2023

Study compares effectiveness of Pfizer vs. Moderna booster COVID vaccines after third dose

In a recent scientific paper published in the journal Nature Microbiology, researchers reproduced two target trials using electronic health records (EHRs) of the Department of Veterans Affairs (VA) to compare the effectiveness of the third dose of BNT162b2 or messenger ribonucleic acid (mRNA)-1273 vaccine among United States (US) veterans.

3 Jan 2023

Scientists collaborate to monitor SARS-CoV-2 RNA among domestic and free-ranging animal species

Researchers collaborated with community partners to monitor SARS-CoV-2 infections among domestic and free-ranging animals with known susceptibility to the virus and proximity to humans in Ohio, United States.

3 Jan 2023

Viral short RNAs detected in SARS-CoV-2 RNA transcriptome

Researchers analyzed the ribonucleic acid (RNA) transcriptome associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV-1-infected human cells.

3 Jan 2023

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

Researchers longitudinally evaluated humoral immune responses to the second and third doses of COVID-19 mRNA vaccines among individuals with and without prior history of SARS-CoV-2 infections.

3 Jan 2023

SHEA advises against COVID screening of asymptomatic patients

Society for Healthcare Epidemiology of America says layers of protection are more effective and have fewer unintended harms

27 Dec 2022

Scientists find key reason for ongoing loss of smell in long-COVID

In a recent study published in the journal Science Translational Medicine, researchers reported that long-term anosmia following coronavirus disease 2019 (COVID-19) could be a result of persistent T-cell mediated inflammation occurring in the olfactory epithelium even after the elimination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the olfactory tissue.

27 Dec 2022

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Researchers described a messenger ribonucleic acid (mRNA)-lipid nanoparticle monkeypox vaccine encoding four conserved monkeypox virus surface proteins which induced monkeypox virus-specific immunity and elicited heterologous protection when challenged with lethal vaccinia virus.

23 Dec 2022

Study shows de novo origination of functional microproteins

In a new study, researchers performed a genomic analysis to investigate the origination of human microproteins of biological importance.

23 Dec 2022

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Researchers evaluated plasma samples from individuals vaccinated with a fourth booster dose of mono- or bivalent mRNA SARS-CoV-2 vaccine to evaluate the recognition and neutralization capacity against the ancestral (D614G) strain and the Omicron BQ.1.1 subvariant.

23 Dec 2022

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

A new paper presents preliminary evidence that a new vaccine candidate, designed to boost immunity in already immunized individuals, and containing the adjuvanted Beta spike variant protein antigen, can induce a potent cross-neutralizing antibody response in non-human primate models that is detectable for up to three months.

23 Dec 2022

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Researchers assesses the real-world efficacy of the novel bivalent COVID-19 vaccine.

22 Dec 2022

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Omicron subvariants effectively escape B-cell immune responses by modifying neutralizing antibody epitopes.

21 Dec 2022

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules.

21 Dec 2022

The potential effects of receiving 2 SARS-CoV-2 vaccine doses on household transmission in England

Researchers assessed the effects of two-dose COVID-19 vaccinations on household SARS-CoV-2 transmission among British residents.

20 Dec 2022

Study finds a lower mortality rate among individuals with myocarditis after mRNA vaccination than those with viral infection–related myocarditis

Researchers compared the prognosis of myocarditis developing after BNT162b2 mRNA COVID-19 vaccination with viral myocarditis over six months.

20 Dec 2022

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

Researchers reported on the vaccine effectiveness of a bivalent vaccine booster administered after ≥2.0 doses of monovalent mRNA vaccines against COVID-19–related hospitalizations among adult individuals 65.0 years or older.

20 Dec 2022

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

Researchers described four novel monoclonal antibodies with potent and broad neutralization activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the current globally dominant Omicron BA.4/BA.5.

20 Dec 2022

First cell-type specific multiomic study of the HIV brain

Researchers identify cell-type-specific differences in HIV integration sites in the brain.

19 Dec 2022

Modulation of insect immunity to control vector-borne diseases

Discussed the current research on the role of molecular mechanisms in mediating immune priming in insects and regulating vector-borne disease transmission.

19 Dec 2022

Ribonucleic Acid News and Research

New type of CRISPR gene scissors discovered

Study compares effectiveness of Pfizer vs. Moderna booster COVID vaccines after third dose

Scientists collaborate to monitor SARS-CoV-2 RNA among domestic and free-ranging animal species

Viral short RNAs detected in SARS-CoV-2 RNA transcriptome

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

SHEA advises against COVID screening of asymptomatic patients

Scientists find key reason for ongoing loss of smell in long-COVID

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Study shows de novo origination of functional microproteins

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

The potential effects of receiving 2 SARS-CoV-2 vaccine doses on household transmission in England

Study finds a lower mortality rate among individuals with myocarditis after mRNA vaccination than those with viral infection–related myocarditis

The effectiveness of a bivalent COVID-19 mRNA booster dose against hospitalization

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

First cell-type specific multiomic study of the HIV brain

Modulation of insect immunity to control vector-borne diseases

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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