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Optical sensing can address unmet clinical needs in orthopedic surgery

Knees and hips wear out. Backs and necks become unstable. Fortunately, orthopedic surgeons specialize in musculoskeletal repair.

6 Jan 2022

Cryo-ET reveals molecular mechanisms underlying gene mutations within the eye

For the first time, University of California, Irvine researchers in collaboration with the Max-Planck Institute of Biochemistry, have revealed, at a molecular level, key structural determinants of the highly specialized rod outer segment (ROS) membrane architecture of the eye, which is instrumental to vision.

5 Jan 2022

Nucleocapsid protein preferentially binds to structured and longer RNA to deliver viral proteins in host circulation

Results from a new study could be crucial in studying the molecular and biochemical basis of SARS-CoV-2 infection at a more granular level and help in strategizing therapeutic solutions to treat and manage COVID-19 effectively.

5 Jan 2022

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

An interdisciplinary research team from the University of Göttingen and Hannover Medical School (MHH) has detected significant changes in the heart muscle tissue of people who died from Covid-19.

23 Dec 2021

Study points toward an alternative drug strategy to stall Alzheimer’s neurodegeneration

Boosting levels of the neurotransmitter norepinephrine with atomoxetine, a repurposed ADHD medication, may be able to stall neurodegeneration in people with early signs of Alzheimer's disease, a study conducted at Emory Brain Health Center suggests.

22 Dec 2021

AI can detect signs of lung-clogging blot clots in electrocardiograms, shows study

Pulmonary embolisms are dangerous, lung-clogging blot clots. In a pilot study, scientists at the Icahn School of Medicine at Mount Sinai showed for the first time that artificial intelligence (AI) algorithms can detect signs of these clots in electrocardiograms (EKGs), a finding which may one day help doctors with screening.

22 Dec 2021

Study demonstrates decreased lung cancer deaths with early detection

A recent, substantial decline in lung cancer deaths is associated with earlier diagnosis of lung cancer than in the past, supporting the need for increased use of screening to save lives, according to a Mount Sinai study published in JAMA Network Open in December.

18 Dec 2021

PET scans can be used to see drug movement in the body to better treat bacterial infections

Treating bacterial infections associated with orthopaedic implants has often been a case of too little, too late.

16 Dec 2021

$1.5 million award helps U-M researchers to gain new window into the inner workings of cells

The precise shapes of proteins at work inside our cells offer essential clues about the processes that drive health and disease. Structural biologists determine the forms of molecular machines, in atomic detail, to better understand how they function or what happens when they malfunction.

15 Dec 2021

Clinical studies show enhanced responses for lymphoma patients treated with axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

12 Dec 2021

Novel AI score predicts risk of death in patients with suspected or known coronary artery disease

A novel artificial intelligence score provides a more accurate forecast of the likelihood of patients with suspected or known coronary artery disease dying within 10 years than established scores used by health professionals worldwide.

11 Dec 2021

Breathlessness in long COVID patients may be linked to decrease in heart performance

A small study has suggested that COVID-19 patients who continue to be short of breath during physical activity one year after recovering from the infection may have suffered heart damage.

9 Dec 2021

Cochlear implant recipients develop new bone formation that leads to long-term residual hearing loss

The majority of cochlear implant recipients develop new bone formation that adversely affects long-term hearing preservation, according to a study appearing in Radiology.

7 Dec 2021

Using soft X-ray tomography for 3D imaging of cell structures in few minutes

Viral pathogens like the SARS-CoV-2 coronavirus change the interior structure of the cells they infect. These changes occur at the level of individual cell components – the organelles – and can provide information on how viral diseases develop.

6 Dec 2021

COVID-19 pandemic likely caused new cancer diagnoses to be delayed, study shows

Restrictions in access to care during the COVID-19 pandemic caused disruptions in the treatment of cancer and other conditions.

6 Dec 2021

Maternal morbidities and outcomes in pregnant women with COVID-19

Researchers aimed to determine whether maternal morbidities and adverse obstetrical outcomes were more frequent in pregnant women with COVID-19.

5 Dec 2021

New insights offered into cell-to-cell propagation of SARS-CoV-2

Evidence from a new study supports previous findings showing SARS-CoV-2 particles inside host cells are morphologically identical to those outside of cells.

2 Dec 2021

First-of-its-kind PET imaging-based tool developed to detect liver inflammation in NAFLD patients

A UC Davis Health team has developed a first-of-its-kind positron emission tomography (PET) scan imaging-based tool to detect liver inflammation in patients affected with non-alcoholic fatty liver disease.

30 Nov 2021

Novel approach uses PSOCT to non-invasively image the depth-resolved collagen organization

Collagen is essential for tissue integrity and stability, and changes in its intrinsic organization are the key features in several important diseases such as scar formation, heart infarction and cancers.

29 Nov 2021

New discovery about tendon and bone attachment reveals strategies for attaching dissimilar materials

Engineers often use nature to inspire new materials and designs. A discovery by a multi-institutional team of researchers and engineers about how tendon and bone attach in the shoulder joint has uncovered previously unsuspected engineering strategies for attaching dissimilar materials.