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Scientists use novel technology for opening blood-brain barrier with implantable ultrasound

One of most potent drugs for treatment of glioblastoma, the most deadly type of brain tumor, can't be used in patients because of two problems. First, it can't reach its target because it's blocked by the blood-brain barrier, a microscopic structure that protects the brain from toxins in the blood. And the conventional formulation for this drug is toxic to the brain.

12 Dec 2019

$Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission$

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission.

8 Dec 2019

Mechanical stress can interrupt bacteria’s ability to survive toxin exposure

A random conversation between two Cornell researchers at a child's birthday party led to a collaboration and new understanding of how bacteria resist toxins, which may lead to new tools in the fight against harmful infections.

5 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

Researchers move one step closer to understanding complex physiology of CKD patients

Researchers have further analyzed a known signaling pathway they believe brings them one step closer to understanding the complex physiology of patients with chronic kidney disease (CKD), which might provide a path to new treatment options.

4 Dec 2019

Climate change and children’s health

UNICEF says that climate change is posing an immense challenge to the health of children worldwide. Though children commonly have the least to do with the actions and attitudes that lead to climate change, they are the ones who will have to bear the brunt of it.

2 Dec 2019

Strong beers that contain gut-friendly bacteria may help fight obesity

Drinking a strong type of beer, particularly a Belgian one, can help combat obesity, promote a good night’s sleep, and may help you live longer, a new study found.

2 Dec 2019

Changes in placenta could mean males born to older mothers more prone to heart problems

A new study in rats shows that older mother rats develop poorer placentas which are in turn related to later risk of heart problems in their male offspring. The study, published in the journal Scientific Reports, shows that both male and female offspring are smaller in size when the mother is older. However, the placental development in older mothers with male fetuses is especially impaired, leading to worse placental function. As a result, heart problems are more common in later life in these offspring, as is high blood pressure.

28 Nov 2019

Placenta changes in older mothers linked to greater odds of heart problems in male offspring

Placenta changes could mean male offspring of older mums more likely to develop heart problems in later life, rat study finds.

28 Nov 2019

Additives in vaping products produce higher aerosol toxins, study finds

The vaping industry is filled with unknowns. Those unknowns are leading to more questions as the number of users dealing with injuries, or in some cases, death, continues to rise.

26 Nov 2019

Newly discovered immune cells play key role in group A streptococcal toxic shock

Recently discovered immune cells called MAIT cells play a key role in group A streptococcal toxic shock, researchers at Karolinska Institutet in Sweden report.

25 Nov 2019

Article reveals new mechanism of programmed aging

Nature has sentenced humans to an inevitable death from the time of birth; the natural instrument of execution is the aging process. According to modern scientific notions, only two root causes of aging can be: stochastic physiological damage or the implementation of a special genetic program in the body.

25 Nov 2019

Researchers assess safety of conditionally immortalized cells for bioartificial kidney application

Here, the research team assessed the safety of conditionally immortalized proximal tubule epithelial cells for bioartificial kidney application, by using in vitro assays and athymic nude rats.

25 Nov 2019

Researchers discover new pathway to 'reprogram' killer cells

Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers at the Institute of Pathology at the University of Bern have now discovered that the mechanism by which certain immune cells kill their target cells can also be used to control the killer cells themselves.

19 Nov 2019

Directional control of protocell's movement could lead to precision drug delivery

Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body.

18 Nov 2019

Broccoli's effects on kidney health may depend on individual's genetics

New research indicates that the benefits of a dietary compound on kidney health may depend on an individual's genetics. The findings, which appear in an upcoming issue of JASN, may be helpful for tailoring interventions to prevent or treat kidney disease.

15 Nov 2019

Caution: blood infections traced to probiotics

Probiotics aren’t harmless, says a new study published on November 7, 2019 in the journal Nature Medicine. In fact, some patients may be put at serious risk by the bacteria in probiotics. Doctors should weigh the risks of probiotics in severely ill or immunocompromised patients before prescribing them, as their benefits may be significantly smaller than the danger in such situations.

13 Nov 2019

Pacemaker-like device improves heart function in patients with chemotherapy-induced cardiomyopathy

With the advent of new therapies, cancer patients are surviving longer than ever before -- but the incidence of side-effect chemotherapy-induced cardiomyopathy (CHIC), or weakness of the heart muscle, is increasing.

13 Nov 2019

Indoor plants do not improve indoor air quality

A new study published in the Journal of Exposure Science & Environmental Epidemiology in November says houseplants aren’t much good at removing pollutants from your home. The researchers systematically reviewed a dozen other studies, looking at factors related to indoor air quality, and especially on the contribution of potted plants to the efficient removal of volatile organic compounds (VOCs).

10 Nov 2019

Botanical product kratom may cause liver toxicity and injury, study finds

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that kratom, a popular and widely available product, may cause liver toxicity and severe liver injury.

10 Nov 2019

Toxins News and Research

Scientists use novel technology for opening blood-brain barrier with implantable ultrasound

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

Mechanical stress can interrupt bacteria’s ability to survive toxin exposure

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

Researchers move one step closer to understanding complex physiology of CKD patients

Climate change and children’s health

Strong beers that contain gut-friendly bacteria may help fight obesity

Changes in placenta could mean males born to older mothers more prone to heart problems

Placenta changes in older mothers linked to greater odds of heart problems in male offspring

Additives in vaping products produce higher aerosol toxins, study finds

Newly discovered immune cells play key role in group A streptococcal toxic shock

Article reveals new mechanism of programmed aging

Researchers assess safety of conditionally immortalized cells for bioartificial kidney application

Researchers discover new pathway to 'reprogram' killer cells

Directional control of protocell's movement could lead to precision drug delivery

Broccoli's effects on kidney health may depend on individual's genetics

Caution: blood infections traced to probiotics

Pacemaker-like device improves heart function in patients with chemotherapy-induced cardiomyopathy

Indoor plants do not improve indoor air quality

Botanical product kratom may cause liver toxicity and injury, study finds

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