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First 3D multicellular brain organoid can screen drugs to control inflammation

The scientists who developed the first 3D multicellular brain organoid with a functional blood brain barrier now report that the model could be a promising platform to screen drugs that could work to control inflammation, which is at the center of many neurological conditions, like ischemic stroke.

30 Jul 2020

Women receiving treatment for cancers are not at increased of being hospitalized for COVID-19

Women receiving standard treatment in New York City for ovarian, uterine, and cervical cancers are not at increased risk of being hospitalized for or dying from COVID-19 due to their cancer, a new study shows.

30 Jul 2020

The toll that COVID-19 takes on the heart

Now, two new studies describe the toll that COVID-19 takes in the heart, increasing the risk of long-term damage even after patients recover. These studies also show that heart damage can even occur in people who did not have severe illness that required hospitalization.

29 Jul 2020

Unexpected neurologic complication identified in severe COVID-19

Physicians working at Cambridge University Hospital NHS Foundation Trust have reported that a significant proportion of patients with severe coronavirus disease 2019 (COVID-19) who required intensive care developed unanticipated disabling neurological deficits that were related to a mononeuritis multiplex.

29 Jul 2020

Clinical study evaluates potential of oral cancer drug to reduce respiratory symptoms of COVID-19

Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and The Ohio State University Wexner Medical Center are conducting a new clinical trial to determine if an oral cancer drug called ibrutinib can also help patients with cancer or other immunocompromised conditions recover from COVID-19.

29 Jul 2020

Pilot study shows cholesterol-lowering medication improves function of coronary arteries

In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.

29 Jul 2020

Platelet hyperreactivity, a unique feature of COVID-19

A new study by Irish researchers and published in the preprint server medRxiv in July 2020 reports a bidirectional relationship between COVID-19 and coagulation abnormalities.

29 Jul 2020

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Researchers at Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation.

29 Jul 2020

Computed tomography can serve as effective tool for diagnosing COVID-19

The use of computed tomography in outpatient computed tomography centers (OCTC) is entirely consistent with the clinical data and global best practices. This is also an effective tool for diagnosing the coronavirus infection COVID-19

29 Jul 2020

Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

A new research paper from China published on the preprint server medRxiv* claims that recurrent positive results for SARS-CoV-2 are due to the presence of low levels of viral RNA fragments and not the shedding of infectious virus particles.

29 Jul 2020

Identification of MTK1 SAPKKK as new human oxidative stress sensor

In an aging society, various studies are being conducted to explore the relationship between active oxygen and aging-related diseases such as cancer, chronic inflammatory diseases, and metabolic syndrome.

28 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

Researchers unlock new insights that may help inform vaccine design for infectious diseases

Vaccination is the most effective public health measure to prevent infectious diseases. Vaccines can greatly reduce the risk of infection by working with the body's natural defenses to safely develop immunity to disease.

28 Jul 2020

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

A new study released today in STEM CELLS Translational Medicine shows promise of a major breakthrough in healing chronic foot ulcers resulting from diabetes.

28 Jul 2020

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

28 Jul 2020

Inflammation News and Research

First 3D multicellular brain organoid can screen drugs to control inflammation

Women receiving treatment for cancers are not at increased of being hospitalized for COVID-19

The toll that COVID-19 takes on the heart

Unexpected neurologic complication identified in severe COVID-19

Clinical study evaluates potential of oral cancer drug to reduce respiratory symptoms of COVID-19

Pilot study shows cholesterol-lowering medication improves function of coronary arteries

Platelet hyperreactivity, a unique feature of COVID-19

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Computed tomography can serve as effective tool for diagnosing COVID-19

Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

Identification of MTK1 SAPKKK as new human oxidative stress sensor

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Researchers unlock new insights that may help inform vaccine design for infectious diseases

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

Study uses MRI imaging to assess the brain matter of WTC responder patients

Varying immune system responses can predict severe COVID-19 outcomes

Ebola survivors have long-lasting severe immune dysfunction

NIDA funding allows Temple scientists to continue critical substance abuse research

Study: Female patients with ankylosing spondylitis can still have children

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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