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New model can simulate and analyze large number of viral infections

It is only 120 millionths of a millimetre in size but can bring entire countries to a standstill: the Corona virus. Even if it were to disappear one day, viral infections will still be among the most frequent and difficult-to-treat diseases in humans.

9 Oct 2020

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

The CRISPR/Cas9 gene-editing tool is one of the most promising approaches to advancing treatments of genetic diseases - including cancer -, an area of research where progress is constantly being made.

9 Oct 2020

Mass production of SARS-CoV-2 ORF8 protein using a chemical-inducible system in tobacco BY-2 cells

Researchers from the Japan Advanced Institute of Science and Technology (JAIST) and Ishikawa Prefectural University, Japan, recently attempted to synthesize the ORF8 protein with the help of a chemical-inducible protein production system using tobacco BY-2 cells. This study has been published demonstrated in the preprint server, bioRxiv.

9 Oct 2020

Virginia Tech to build a cyberinfrastructure for wastewater antibiotic-resistant gene monitoring

Antibiotic resistance is a grand challenge of the 21st century. According to the U.S. Centers for Disease Control and Prevention, antibiotic resistance rates are increasing globally, with an estimated 35,000 related deaths per year in the United States in 2019, compared to 23,000 in 2013.

8 Oct 2020

Breakthrough genetic discovery into the cause of severe neurological conditions

Researchers have made a breakthrough genetic discovery into the cause of a spectrum of severe neurological conditions.

8 Oct 2020

Research uncovers a novel way of preventing or treating epilepsy

Epileptic seizures often originate in small, localized areas of the brain where neurons abnormally fire in unison.

8 Oct 2020

Neutralizing responses to infection relatively common in COVID-19

A new study has shown that severe coronavirus disease 2019 (COVID-19) is associated with unique B cell receptor (BCR) signatures and multiclonal neutralizing responses against the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Oct 2020

Diet and folic acid can influence pregnancy outcomes

Healthy dietary choices are not only important for expectant mothers during the early months of pregnancy but equally important in the months prior to conception.

8 Oct 2020

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

The compound thymoquinone (TQ) selectively kills prostate cancer cells at advanced stages, according to a new study published in Oncogene.

8 Oct 2020

Experimental Chinese SARS-CoV-2 vaccine appears safe in early trials

A new study published on the preprint server medRxiv in October 2020 reports the findings of a phase I trial of an inactivated SARS-CoV-2 vaccine, demonstrating that it can elicit a potent immune response without significant adverse reactions.

7 Oct 2020

Plasma ABO protein is a causal risk factor for severe COVID-19

Researchers used an integrative genomics approach to find the genes responsible for COVID-19 and its severity.

7 Oct 2020

Study identifies the exact neurons that are most affected by epilepsy

Epilepsy is one of the most common neurological diseases. It is caused by a malfunction in brain cells and is usually treated with medicines that control or counteract the seizures.

7 Oct 2020

Oral cancer pain may help predict metastasis

Oral cancer is more likely to spread in patients experiencing high levels of pain, according to a team of researchers at New York University College of Dentistry that found genetic and cellular clues as to why metastatic oral cancers are so painful.

7 Oct 2020

Endocannabinoids in the body can help fight intestinal infections

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.

7 Oct 2020

Biodegradable microneedle patch for local therapeutic gene delivery

There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections. The therapies work by delivering genes into the patients' cells, which then produce therapeutic proteins to treat the affliction.

7 Oct 2020

Rare gene mutations can cause cerebral palsy, confirms new study

An international research team including the University of Adelaide has found further evidence that rare gene mutations can cause cerebral palsy, findings which could lead to earlier diagnosis and new treatments for this devastating movement disorder.

7 Oct 2020

Study may explain why cannabis plant can reduce symptoms of various bowel conditions

7 Oct 2020

Researchers decipher evolution of the Y chromosome in great apes

New analysis of the DNA sequence of the male-specific Y chromosomes from all living species of the great ape family helps to clarify our understanding of how this enigmatic chromosome evolved.

6 Oct 2020

Salk physician-scientist has been named an NIH Director's New Innovator for 2020

Salk Institute Assistant Professor Edward Stites has been named an NIH Director's New Innovator for 2020 as part of the National Institutes of Health's High-Risk, High-Reward Research Program.

6 Oct 2020

ACGT awards $500,000 grant to advance strategies for treating solid tumors

With a $500,000 Research Grant from Alliance for Cancer Gene Therapy, Sidi Chen, PhD, assistant professor in the Department of Genetics and Systems Biology Institute at Yale School of Medicine and member of Yale Cancer Center, will advance a versatile and highly scalable strategy he's been developing and calling MAEGI -- Multiplexed Activation of Endogenous Genes as an Immunotherapy.

6 Oct 2020