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Study highlights need to improve end-of-life care for all patients with serious illnesses

Historically, efforts to improve end-of-life care have focused primarily on patients with cancer. But few studies have looked at the quality of end-of-life care for patients with other serious illnesses, such as lung, kidney or heart failure or dementia.

27 Jun 2016

Study highlights lack of guidance on deintensifying diabetic regimens

Patients with Type 2 diabetes often receive unnecessarily intensive treatment for long durations, increasing their risk of severe hypoglycaemia, research shows.

25 Jun 2016

Oncogene signatures could help design new drug treatments for breast cancer

Drug treatments for breast cancer patients might soon be designed based on the unique genetic autograph of their tumor.

25 Jun 2016

NCX1 protein could help prevent progression of heart failure

A protein known to be crucial for maintaining the balance of calcium in cells could prove useful in halting the progression of heart failure.

24 Jun 2016

Researchers reveal integrins could be key to survival mechanism in cancer cells

Cancer cells appear to depend on an unusual survival mechanism to spread around the body, according to an early study led by Queen Mary University of London. The discovery could help with future development of novel treatments to prevent metastasis and secondary tumours.

24 Jun 2016

Researchers engineer revolutionary new approach to combat cancer treatment resistance

Math, biology and nanotechnology are becoming strange, yet effective bed-fellows in the fight against cancer treatment resistance. Researchers at the University of Waterloo and Harvard Medical School have engineered a revolutionary new approach to cancer treatment that pits a lethal combination of drugs together into a single nanoparticle.

24 Jun 2016

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

There is merit in looking at the use of wearable biosensors to detect whether opioid users stay focused on their rehabilitation programs.

23 Jun 2016

Two simple measures can help decrease incidence of POCD in older patients

Post-operative cognitive dysfunction (POCD), a condition mostly observed in older patients following surgery under general anesthesia, is characterized by impaired memory and concentration. The impairment may be temporary or permanent and incapacitating.

23 Jun 2016

Searing temperatures can be inherently dangerous to vulnerable children, older adults

The searing, record-setting temperatures in the West and Southwest United States flared a warning that extreme heat could be commonplace across much of the country this summer.

23 Jun 2016

Walnut consumption linked to reduced risk of developing physical function impairments in older women

A new study published in the Journal of Nutrition suggests that consuming 1-2 servings of walnuts per week (1/4 cup per serving) was associated with reduced risk of developing impairments in physical function, which helps enable older women to maintain independence throughout the aging process.

23 Jun 2016

Researchers uncover new clues about role of glucosamine in early embryonic development

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early in embryonic development, the babies are exposed to higher levels of glucose in maternal blood.

23 Jun 2016

New study identifies 40 genes susceptible to migraine

Migraine is one of the most common neurological disorders and it affects 1 out of 7 people in the world. Painful and incapacitating, it has multi-factor origins, with the participation of environmental triggering factors and several altered genes in each individual.

23 Jun 2016

Highly structured nutrition therapy provides substantial impact on A1C, body weight and lipid profiles

Researchers at Joslin Diabetes Center have announced the results of a study that may change how nutrition therapy is delivered to overweight and obese patients with type 2 diabetes.

22 Jun 2016

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Scientists at the University of Massachusetts Medical School have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication.

22 Jun 2016

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Researchers from the University of Chicago have shown that microbiota—the bacteria, viruses and other microbes living on the skin and in the digestive system—play an important role in the body's ability to accept transplanted skin and other organs.

22 Jun 2016

New CAR-based therapy using combined cancer target could be effective for solid tumors

Chimeric antigen receptors (CARs), engineered from a patient's own immune cells, have been successful for treating blood cancers, but using CARs for solid tumors has been limited by side effects to normal tissues containing the protein targeted by the engineered cells.

22 Jun 2016

Experts develop set of resolutions, conclusions to provide clarity on testosterone therapy

In an effort to address widespread concerns related to testosterone deficiency (TD) and its treatment with testosterone therapy, a group of international experts has developed a set of resolutions and conclusions to provide clarity for physicians and patients.

21 Jun 2016

Patient navigators could help improve comprehensive cancer screening rates among low-income, ethnic minorities

A clinical trial conducted by Massachusetts General Hospital investigators has found that the use of patient navigators - individuals who assist patients in receiving health care services - may improve comprehensive cancer screening rates among patient populations not likely to receive recommended screenings.

21 Jun 2016

Scientists identify on/off obesity-induced switch to slow cancer progression

Having established that excessive fat tissue can fuel the growth of certain cancers, researchers have turned their attention to the molecular mechanisms involved in the process in the hopes of developing new cancer treatments.

21 Jun 2016

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Researchers have identified a new signaling pathway that helps cancer cells cope with the lack of oxygen found inside tumors. These are the results of a study published in Nature Cell Biology on June 20, and led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, Princess Margaret Cancer Center, the University of Toronto, Harvard Medical School and Oxford University.

21 Jun 2016

Medical School News and Research

Study highlights need to improve end-of-life care for all patients with serious illnesses

Study highlights lack of guidance on deintensifying diabetic regimens

Oncogene signatures could help design new drug treatments for breast cancer

NCX1 protein could help prevent progression of heart failure

Researchers reveal integrins could be key to survival mechanism in cancer cells

Researchers engineer revolutionary new approach to combat cancer treatment resistance

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

Two simple measures can help decrease incidence of POCD in older patients

Searing temperatures can be inherently dangerous to vulnerable children, older adults

Walnut consumption linked to reduced risk of developing physical function impairments in older women

Researchers uncover new clues about role of glucosamine in early embryonic development

New study identifies 40 genes susceptible to migraine

Highly structured nutrition therapy provides substantial impact on A1C, body weight and lipid profiles

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

New CAR-based therapy using combined cancer target could be effective for solid tumors

Experts develop set of resolutions, conclusions to provide clarity on testosterone therapy

Patient navigators could help improve comprehensive cancer screening rates among low-income, ethnic minorities

Scientists identify on/off obesity-induced switch to slow cancer progression

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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