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10 simple points to know and monitor alcohol intake

Much the same way individuals are encouraged to know their blood pressure and cholesterol numbers to maintain a healthy lifestyle, a new editorial in the Journal of Psychopharmacology urges the European public to know and monitor their alcohol intake number using a simple 10 point plan.

7 Jan 2014

Blueprint Medicines closes $25 million Series B financing

Blueprint Medicines today announced the completion of a $25 million Series B financing. The oncology-focused investor, Nextech Invest Ltd., led the round, which also included founding investors Third Rock Ventures and Fidelity Biosciences as well as public investors Biotech Value Fund, L.P., Casdin Capital, LLC and other undisclosed investors.

7 Jan 2014

ERYTECH proposes to broaden lead product in solid tumors, begins Phase II study in pancreatic cancer

ERYTECH Pharma (Euronext Paris: FR0011471135 - ERYP), a French biopharmaceutical company that develops innovative treatments for acute leukemia and other oncology indications with unmet medical needs, provides an update on its development plans to broaden the scope of its lead product ERYASP into the large field of solid tumors and announces the launch of a Phase II study in pancreatic cancer.

7 Jan 2014

New guidelines provide screening recommendations for people at higher risk of developing lung cancer

Alarmingly, more than 200,000 Americans will be diagnosed with lung cancer this year and nearly 160,000 people will die of the disease. In fact, according to the American Cancer Society, lung cancer takes more lives each year than colorectal, breast and prostate cancers combined.

7 Jan 2014

Study uncovers how enzymes could be used to identify predisposition to ROS-related diseases

A UT Arlington chemist doing National Science Foundation-funded research on enzymes that regulate human biology has uncovered characteristics that could be used to identify predisposition to conditions such as heart disease, diabetic ulcers and some types of cancer.

6 Jan 2014

Marina Biotech, Mirna modify license agreement regarding development of microRNA-based therapeutics

Marina Biotech, Inc., a leading oligonucleotide-based drug discovery and development company, and Mirna Therapeutics, Inc., a privately-held biotechnology company pioneering microRNA replacement therapy for cancer, announced today that they have amended their license agreement regarding the development and commercialization of microRNA-based therapeutics utilizing Mirna's proprietary microRNAs and Marina Biotech's novel SMARTICLES liposomal delivery technology.

3 Jan 2014

Biologists discover effective strategy that could prevent immune system from rejecting grafts

Biologists at UC San Diego have discovered an effective strategy that could prevent the human immune system from rejecting the grafts derived from human embryonic stem cells, a major problem now limiting the development of human stem cell therapies.

3 Jan 2014

Scientists discover new class of cells expressing olfactory receptors in human airways

Your nose is not the only organ in your body that can sense cigarette smoke wafting through the air. Scientists at Washington University in St. Louis and the University of Iowa have showed that your lungs have odor receptors as well.

3 Jan 2014

UPV/EHU-University study shows that weekend alcohol consumption may affect DNA

A preliminary study led by a UPV/EHU-University of the Basque Country researcher in collaboration with the Autonomous University of Nayarit, in Mexico, indicates that weekend alcohol consumption may affect DNA.

30 Dec 2013

Elementary school administrator donates healthy kidney to total stranger

Terie Cota, an elementary school administrator from Santa Maria, Calif., describes herself as an "average 56-year-old woman." She has been married 34 years, is the mother of four sons and grandmother of two little girls. But there is nothing average about Terie Cota because she chose to do something few others would think to do: She donated one of her healthy kidneys to a total stranger.

28 Dec 2013

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

We are fundamentally dependent on the presence of copper in the cells of the body. Copper is actually part of the body's energy conversion and protective mechanisms against oxygen radicals, as well as part of the immune system, and it also has great importance for the formation of e.g. hormones and neurotransmitters.

28 Dec 2013

Takeda terminates development activities for fasiglifam (TAK-875)

Takeda Pharmaceutical Company Limited (Takeda) announced today that it has decided voluntarily to terminate the development activities for fasiglifam (TAK-875), an investigational treatment for type 2 diabetes, due to concerns about liver safety.

27 Dec 2013

Researchers study health consequences of RTE proliferation that occurs in aging tissues

The genomes of organisms from humans to corn are replete with "parasitic" strands of DNA that, when not suppressed, copy themselves and spread throughout the genome, potentially affecting health. Earlier this year Brown University researchers found that these "retrotransposable elements" were increasingly able to break free of the genome's control in cultures of human cells.

27 Dec 2013

Three foods can help prevent Alzheimer's disease

The number of Americans with Alzheimer's is projected to triple by 2050. While there isn't a cure for Alzheimer's, certain lifestyle changes can help prevent cognitive decline.

27 Dec 2013

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations.

26 Dec 2013

Diflunisal drug reduces neurological decline in patients with familial transthyretin amyloidosis

A recent study led by researchers from the Amyloidosis Center at Boston University School of Medicine and Boston Medical Center demonstrates that diflunisal, a generic anti-inflammatory drug, successfully reduced neurological decline and preserved the quality of life in patients with familial transthyretin amyloidosis. Diflunisal is an inexpensive and safe medication marketed over the past 40 years for arthritis and pain.

25 Dec 2013

Paired exchange and incompatible kidney transplant program launched by UAB

Ann Marie Reynolds, a 32-year-old who has been in and out of hospitals fighting chronic kidney disease since she was a teenager, had a less than 1 percent chance of receiving a kidney without the University of Alabama at Birmingham's groundbreaking organ donation system that helped her and two other hard-to-match patients get kidneys in a three-way, incompatible kidney exchange earlier this year.

24 Dec 2013

Researchers report new gene delivery method that targets tumor blood vessels

Working in mice, researchers at Washington University School of Medicine in St. Louis report developing a gene delivery method long sought in the field of gene therapy: a deactivated virus carrying a gene of interest that can be injected into the bloodstream and make its way to the right cells.

24 Dec 2013

Hazards of dietary supplements, new birth control device explored

Dietary supplements account for nearly 20 percent of drug-related liver injuries reported by hospitals, according to The New York Times, while a surge in adverse event reports about Essure, a device hailed as next generation birth control, is explored by the Chicago Tribune. NPR looks at the increase in newborn screening tests.

23 Dec 2013

First Edition: December 23, 2013

The early morning highlights from the major news organizations examine today's deadline for enrolling for health insurance that would begin Jan. 1, as well as a variety of other health law stories and several articles on mental health issues:

23 Dec 2013

Liver News and Research

10 simple points to know and monitor alcohol intake

Blueprint Medicines closes $25 million Series B financing

ERYTECH proposes to broaden lead product in solid tumors, begins Phase II study in pancreatic cancer

New guidelines provide screening recommendations for people at higher risk of developing lung cancer

Study uncovers how enzymes could be used to identify predisposition to ROS-related diseases

Marina Biotech, Mirna modify license agreement regarding development of microRNA-based therapeutics

Biologists discover effective strategy that could prevent immune system from rejecting grafts

Scientists discover new class of cells expressing olfactory receptors in human airways

UPV/EHU-University study shows that weekend alcohol consumption may affect DNA

Elementary school administrator donates healthy kidney to total stranger

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

Takeda terminates development activities for fasiglifam (TAK-875)

Researchers study health consequences of RTE proliferation that occurs in aging tissues

Three foods can help prevent Alzheimer's disease

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

Diflunisal drug reduces neurological decline in patients with familial transthyretin amyloidosis

Paired exchange and incompatible kidney transplant program launched by UAB

Researchers report new gene delivery method that targets tumor blood vessels

Hazards of dietary supplements, new birth control device explored

First Edition: December 23, 2013

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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