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HIV-derived antibacterial compounds could be potential treatments for drug-resistant bacterial infections

A team of researchers at the University of Pittsburgh has developed antibacterial compounds, derived from the outer coating of HIV, that could be potential treatments for drug-resistant bacterial infections and appear to avoid generating resistance. These new agents are quite small, making them inexpensive and easy to manufacture.

20 Jun 2013

Staph-killing compound may be effective against osteomyelitis

Osteomyelitis - a debilitating bone infection most frequently caused by Staphylococcus aureus ("staph") bacteria - is particularly challenging to treat.

20 Jun 2013

Endosonographic aspiration procedures result in greater diagnostic yield in treating pulmonary sarcoidosis

Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with bronchoscopic biopsy, the current diagnostic standard, resulted in greater diagnostic yield, according to a study in the June 19 issue of JAMA.

19 Jun 2013

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.

19 Jun 2013

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

The National Institutes of Health has awarded $12.7 million to match nine academic research groups with a selection of pharmaceutical industry compounds to explore new treatments for patients in eight disease areas, including Alzheimer's disease, Duchenne muscular dystrophy and schizophrenia.

19 Jun 2013

Aspirin slows accumulation of DNA mutations in abnormal cells, points UCSF scientist

Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells in at least one pre-cancerous condition.

19 Jun 2013

Research findings may pave way for new strategy to combat lung cancer

Recent research has shown that cancer cells have a much different - and more complex - metabolism than normal cells. Now, scientists at The University of Texas at Dallas have found that exploiting these differences might provide a new strategy to combat lung cancer.

19 Jun 2013

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.

18 Jun 2013

Two MRI measurements of abdominal aorta associated with future cardiovascular events

In a study of more than 2,000 adults, researchers found that two MRI measurements of the abdominal aorta - the amount of plaque in the vessel and the thickness of its wall - are associated with future cardiovascular events, such as a heart attack or stroke. Results of the study are published online in the journal Radiology.

18 Jun 2013

Pyrvinium pamoate inhibits drug-resistant prostate cancer

A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Investigators recruit subjects for Boston Children's Hand Transplant Program

Boston Children's Hospital today announced that investigators are now recruiting subjects for the world's first pediatric hand transplant program. The Boston Children's Hand Transplant Program, led by principal investigator Amir Taghinia, MD, and William Harmon, MD, is a research-based program that will offer bi-lateral hand transplants for children living without two functioning hands.

17 Jun 2013

Study shows how cancer cells interact with healthy cells to migrate around the body during metastasis

A mechanism that cells use to group together and move around the body - called 'chase and run' - has been described for the first time by scientists at UCL.

17 Jun 2013

Pathway Genomics to provide genetic testing for BRCA gene linked to breast, ovarian cancers

Pathway Genomics led the evening news Friday with an announcement that it could begin offering affordable access to genetic testing for the BRCA gene linked to breast and ovarian cancers in the wake of a Supreme Court ruling that eliminated another company's monopoly on the test.

15 Jun 2013

AIFA approves pricing and reimbursement conditions for InterMune's Esbriet

InterMune, Inc. today announced that the Board of the Italian Drug Agency has approved the pricing and reimbursement conditions for Esbriet (pirfenidone), and that the agreement has been published in the Official Gazette, the official journal of the government of Italy.

15 Jun 2013

MemoryShape Breast Implants receive FDA approval

The U.S. Food and Drug Administration today approved the MemoryShape Breast Implant to increase breast size (augmentation) for use in women at least 22 years old and to rebuild breast tissue (reconstruction) in women of any age.

15 Jun 2013

Scientists genetically engineer E. coli bacteria addicted to caffeine

The latest episode in the American Chemical Society's award-winning Global Challenges/Chemistry Solutions podcast series describes bacteria that are "addicted" to caffeine in a way that promises practical uses ranging from decontamination of wastewater to bioproduction of medications for asthma.

14 Jun 2013

Viewpoints: 'Tyranny' over insurers; Obama's promises; Rep. Franks's abortion claim

Many of us wish that Obamacare were a simpler system, one that directly provided health insurance. Political reality, unfortunately, ensured that many people will receive coverage from private insurers, selling policies - often with subsidies - on the "exchanges". And naturally enough, the Obama administration is teaming up with the insurers and other parts of the health industry to help inform Americans of the benefits to which they will be legally entitled, starting Jan. 1 (Paul Krugman, 6/12).

14 Jun 2013

Data demonstrate benefits of nurse-led programme on patient self-management of RA

Data first presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism demonstrate the benefits of a nurse-led programme on patient self-management and the management of rheumatoid arthritis co-morbidities.

14 Jun 2013

Research findings could enable early screening of HCC patients for more aggressive treatment

Latest research findings by scientists at the Cancer Science Institute of Singapore at the National University of Singapore could enable early screening of patients with hepatocellular carcinoma, a major form of liver cancer, for more aggressive treatment to improve survival rate.

14 Jun 2013

Penn Medicine researchers identify key molecular player in recurrent breast cancer

According to the American Cancer Society, nearly 40,000 women in the United States will succumb to breast cancer this year. Most of these women will die not from the primary tumor but rather tumor recurrence - the reappearance of the disease following treatment.

14 Jun 2013

Lungs News and Research

HIV-derived antibacterial compounds could be potential treatments for drug-resistant bacterial infections

Staph-killing compound may be effective against osteomyelitis

Endosonographic aspiration procedures result in greater diagnostic yield in treating pulmonary sarcoidosis

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

Aspirin slows accumulation of DNA mutations in abnormal cells, points UCSF scientist

Research findings may pave way for new strategy to combat lung cancer

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Two MRI measurements of abdominal aorta associated with future cardiovascular events

Pyrvinium pamoate inhibits drug-resistant prostate cancer

Investigators recruit subjects for Boston Children's Hand Transplant Program

Study shows how cancer cells interact with healthy cells to migrate around the body during metastasis

Pathway Genomics to provide genetic testing for BRCA gene linked to breast, ovarian cancers

AIFA approves pricing and reimbursement conditions for InterMune's Esbriet

MemoryShape Breast Implants receive FDA approval

Scientists genetically engineer E. coli bacteria addicted to caffeine

Viewpoints: 'Tyranny' over insurers; Obama's promises; Rep. Franks's abortion claim

Data demonstrate benefits of nurse-led programme on patient self-management of RA

Research findings could enable early screening of HCC patients for more aggressive treatment

Penn Medicine researchers identify key molecular player in recurrent breast cancer

The ultimate guide to lung research tools and protocols eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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