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Researchers shown how BRCA1 inactivation raises cancer risk

Working with human breast cells, researchers at the Johns Hopkins Kimmel Cancer Center have shown how the inactivation of a single copy of the breast cancer gene BRCA1 leaves breast cells vulnerable to cancer by reducing their ability to repair DNA damage, causing genetic instability.

12 Dec 2011

HER2 proteins do not predict breast cancer patient's outcome after Herceptin treatment

Precisely quantifying the amount of three different HER growth proteins, along with several other proteins believed linked to breast cancer, did not predict a patient's outcome after treatment for HER2-Positive Breast Cancer with Herceptin, say Mayo Clinic researchers.

12 Dec 2011

New method to design Alzheimer's antibodies

Researchers at Rensselaer Polytechnic Institute have developed a new method to design antibodies aimed at combating disease. The surprisingly simple process was used to make antibodies that neutralize the harmful protein particles that lead to Alzheimer's disease.

12 Dec 2011

Study explains molecular basis for cherubism disease

The Samuel Lunenfeld Research Institute's Drs. Frank Sicheri, Tony Pawson and Sebastian Guettler, in collaboration with Dr. Robert Rottapel at the Ontario Cancer Institute, have uncovered the detailed architecture of a crucial component of Tankyrase, a protein linked to the bone development disorder cherubism and involved in a myriad of cellular processes.

9 Dec 2011

The contraceptive pill could reduce risk of ovarian and uterine cancer in nuns

Professor Roger Short, from the University of Melbourne, and Dr Kara Britt, from Monash University, argue in a comment piece in The Lancet, that since the contraceptive pill reduces overall mortality and mortality specifically linked to ovarian and uterine cancer, nuns should be given the pill for health, rather than contraceptive, reasons.

9 Dec 2011

ZEN bust-enhancing supplements may increase risk of breast cancer

Women who use bust-enhancing dietary supplements containing the mycoestrogen zearalenone (ZEN), a naturally occurring toxin that widely contaminates agricultural products, could be increasing their risk of breast cancer. That is the warning from breast health experts in a paper published online ahead of print publication in the January issue of IJCP, the International Journal of Clinical Practice.

9 Dec 2011

Patients having stray tumor cells in the blood should receive aggressive treatment

The presence of circulating tumor cells in the blood appears to have no relationship to survival in women who have just been diagnosed with inflammatory breast cancer, according to new research from Fox Chase Cancer Center.

9 Dec 2011

Dramatic rise in substance abuse treatment admission rates from 1999-2009

A new report shows that while the overall rate of substance abuse treatment admissions among those aged 12 and older in the United States has remained nearly the same from 1999 to 2009, there has been a dramatic rise (430 percent) in the rate of treatment admissions for the abuse of prescription pain relievers during this period.

9 Dec 2011

Ovary removal in younger women may lead to low-bone mineral density, arthritis

Having both ovaries removed before age 45 is strongly associated with low-bone mineral density and arthritis in later years, according to a new study by Johns Hopkins oncologists and epidemiologists. The analysis covered several thousand women who took part in a U.S. government-sponsored, multiyear national health study, and excluded women whose ovaries were removed due to cancer.

9 Dec 2011

Binge drinking linked to risk of sexual victimization among freshman women

Many young women who steer clear of alcohol while they're in high school may change their ways once they go off to college. And those who take up binge drinking may be at relatively high risk of sexual assault, according to a study in the January issue of the Journal of Studies on Alcohol and Drugs.

9 Dec 2011

High gut flora protects children against allergies

High diversity and a variety of bacteria in the gut protect children against allergies as opposed to some individual bacterial genera. These are the findings of a comprehensive study of intestinal microflora (gut flora) in allergic and healthy children, which was conducted at Linköping University in Sweden.

9 Dec 2011

Breakthrough advance in tackling dangerous 'bad' cholesterol in the body

Scientists from the University of Leicester and University of California Los Angeles (UCLA) have announced a breakthrough advance in tackling dangerous 'bad' cholesterol in the body.

9 Dec 2011

Sebelius overturns FDA on morning after pill access

The Health and Human Services Secretary Kathleen Sebelius this Wednesday has overturned the Food and Drug Administration's plan to remove the age limit on who can buy Teva Pharmaceutical Industries Ltd's Plan B One-Step pill – commonly known as the “morning after pill” without a prescription.

8 Dec 2011

Clues to underlying causes of atherosclerosis

By changing the behavior of certain cells within human blood vessels, Cornell University researchers have discovered important clues as to the underlying causes of atherosclerosis - a discovery researchers hope can lead to more targeted drug therapies for the prevention of the disease.

8 Dec 2011

Young women who binge drink are at high risk of sexual assault

Many young women who steer clear of alcohol while they're in high school may change their ways once they go off to college. And those who take up binge drinking may be at relatively high risk of sexual assault, according to a University at Buffalo-led study in the January issue of the Journal of Studies on Alcohol and Drugs.

8 Dec 2011

Two new research studies to help colicky infant and their parents

The wail of a colicky baby can send parents into near panic and cause sleepless nights for all. Now, two innovative research studies are being conducted at the new UT Physicians Colic Clinic at The University of Texas Health Science Center at Houston (UTHealth) to help both crying babies and their worried parents.

8 Dec 2011

First study to identify molecular mechanism that links inflammation to cancer epigenetics

Johns Hopkins Kimmel Cancer Center scientists report that sharp rises in levels of reactive oxygen molecules, and the inflammation that results, trigger biochemical changes that silence genes in a pattern often seen in cancer cells. The researchers confirmed this gene-silencing effect in mice that develop inflammation-induced colon cancer.

8 Dec 2011

Simple mindful eating, stress-reduction techniques help prevent weight gain in obese women

Many dread gaining weight during the holiday season, but there may be hope for those who find that stress causes them to reach for yet another helping of holiday goodies. In a study by UCSF researchers published online in the Journal of Obesity, mastering simple mindful eating and stress-reduction techniques helped prevent weight gain even without dieting.

8 Dec 2011

Arsenic in rice worrisome

Studies have shown that rice takes up more arsenic from soil than other crops. Now a new study shows that higher arsenic levels are ingested by women who eat as little as half a cup of cooked rice in a day. Currently, there are no limits on the amount of allowable arsenic in rice in the United States. But the Environmental Protection Agency has set arsenic limits in water of 10 parts per billion.

7 Dec 2011

Longer lives of US Presidents contrary to popular belief

According to Dr. Michael Roizen U.S. Presidents may be aging twice as fast as the rest of us while they occupy the Oval Office. Roizen, chairman of the Wellness Institute at the esteemed Cleveland Clinic, is the developer of RealAge, whose premise is that one’s calendar age isn’t necessarily in sync with the actual wear and tear on the body.

7 Dec 2011