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Excessive abuse of alcohol causes structural damage at molecular level to the brain

Joint research between the University of the Basque Country (UPV/EHU) and the University of Nottingham has identified, for the first time, the structural damage caused at a molecular level to the brain by the chronic excessive abuse of alcohol.

13 Jun 2014

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

Data presented today at the European League Against Rheumatism Annual Congress showed that a significant number of patients with psoriatic arthritis (PsA) were not receiving doses of the tumour necrosis factor-alpha (TNFα) inhibitor adalimumab necessary to achieve optimal clinical benefit.

12 Jun 2014

New path may lead to powerful adjunctive novel therapy for PTSD treatment

There are currently only two FDA-approved medications for the treatment of posttraumatic stress disorder (PTSD) in the United States. Both of these medications are serotonin uptake inhibitors. Despite the availability of these medications, many people diagnosed with PTSD remain symptomatic, highlighting the need for new medications for PTSD treatment.

12 Jun 2014

Bacteria must be considered part of overall pathology of atherosclerosis

Scientists believe they have an explanation for the axiom that stress, emotional shock, or overexertion may trigger heart attacks in vulnerable people. Hormones released during these events appear to cause bacterial biofilms on arterial walls to disperse, allowing plaque deposits to rupture into the bloodstream, according to research published in published today in mBio-, the online open-access journal of the American Society for Microbiology.

11 Jun 2014

Novel bone implants can keep germs at bay

Hospital germs can be fatal, since they are resistant to antibiotics. As a result, alternative methods of defense against bacteria are in demand. Fortunately, a German-French research team has been able to develop bone implants that keep the germs at bay.

11 Jun 2014

Modified mosquitoes produce sperm that only creates males

Scientists have modified mosquitoes to produce sperm that will only create males, pioneering a fresh approach to eradicating malaria.

11 Jun 2014

Combination of novel molecular imaging techniques can help predict spread of cancer, patient survival

A simple noninvasive blood test matched with state-of-the-art molecular imaging of individual cells could help oncologists understand their patients' chances of survival, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

10 Jun 2014

Celsus’ expert highlights serious side effects of topical corticosteroids

A 2013 Mayo Clinic study involving more than 140,000 patients revealed that skin disorders are the most common nonacute reason Americans seek health care.

9 Jun 2014

Protein-kinase interactions offer a new way to fight antimalarial drug resistance

When it comes to the emergence of antimalarial drug resistance, it's not a question of 'if' but 'when'. In order to keep up with the quickly evolving Plasmodium parasite - the cause of malaria - new ways to treat and control the disease must be found.

9 Jun 2014

Research finding paves way for targeted approaches to treating cancer patients

Twelve years ago, UNC School of Medicine researcher Brian Strahl, PhD, found that a protein called Set2 plays a role in how yeast genes are expressed - specifically how DNA gets transcribed into messenger RNA. Now his lab has found that Set2 is also a major player in DNA repair, a complicated and crucial process that can lead to the development of cancer cells if the repair goes wrong.

9 Jun 2014

Advances in understanding of genetics of CAD lead to more therapeutic targets

Advances in the understanding of the genetics of coronary artery disease, or CAD, will revitalize the field and lead to more therapeutic targets for new medicines to combat this common disease, suggests a genetics expert from the Perelman School of Medicine at the University of Pennsylvania in a Perspective article in the new issue of Science Translational Medicine.

9 Jun 2014

Scientists develop new molecule for monitoring drug concentration

Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants.

9 Jun 2014

Gene variants that lead to longer telomeres boost brain cancer risk

New genomic research led by UC San Francisco scientists reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas.

9 Jun 2014

Eucodis Bioscience, INVISTA to develop bio-derived processes for production of industrial chemicals

INVISTA and Eucodis Bioscience, an Austrian biotechnology company with strong expertise in enzyme engineering and industrial enzyme development, announce a collaboration for the screening and engineering of enzymes to further develop bio-derived processes for the production of industrial chemicals.

5 Jun 2014

Scientists reproduce chromosomal modifications in human cells that cause certain cancer

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Centro Nacional de Investigaciones Oncol-gicas (CNIO) have succeeded in reproducing, in human cells, the chromosomal translocations that cause two types of cancer: acute myeloid leukemia and Ewing's sarcoma.

5 Jun 2014

Discovery of IDE may lead to new treatment approaches for diabetes

The discovery of an inhibitor of the Insulin Degrading Enzyme (IDE), a protein responsible for the susceptibility of diabetes because it destroys insulin in the body, may lead to new treatment approaches for diabetes.

5 Jun 2014

High dose vitamin C therapy may have positive effect on Epstein-Barr virus infection

The Epstein-Barr virus (EBV) is a member of the herpes family that targets lymphocytes and epithelial cells. While the infection is usually benign, it can in some cases lead to acute infectious mononucleosis and can impair the immune system. EBV is also linked to several malignancies. There is currently no cure for removing EBV infections and very little success treating acute EBV infection and mononucleosis with drugs.

4 Jun 2014

Researchers reproduce tumor chromosomal translocations in human cells

Scientists from the Spanish National Cancer Research Centre and the Spanish National Cardiovascular Research Centre have been able to reproduce, for the first time in human cells, chromosomal translocations associated with two types of cancer: acute myeloid leukaemia and Ewing's sarcoma.

4 Jun 2014

Brown University researchers develop new biochip sensor to measure glucose levels in saliva

Researchers from Brown University have developed a new biochip sensor that can selectively measure concentrations of glucose in a complex solution similar to human saliva. The advance is an important step toward a device that would enable people with diabetes to test their glucose levels without drawing blood.

4 Jun 2014

Researchers figure out way to disable a part of SARS virus

A Purdue University-led research team has figured out how to disable a part of the SARS virus responsible for hiding it from the immune system; a critical step in developing a vaccine against the deadly disease.

4 Jun 2014

Enzyme News and Research

Excessive abuse of alcohol causes structural damage at molecular level to the brain

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

New path may lead to powerful adjunctive novel therapy for PTSD treatment

Bacteria must be considered part of overall pathology of atherosclerosis

Novel bone implants can keep germs at bay

Modified mosquitoes produce sperm that only creates males

Combination of novel molecular imaging techniques can help predict spread of cancer, patient survival

Celsus’ expert highlights serious side effects of topical corticosteroids

Protein-kinase interactions offer a new way to fight antimalarial drug resistance

Research finding paves way for targeted approaches to treating cancer patients

Advances in understanding of genetics of CAD lead to more therapeutic targets

Scientists develop new molecule for monitoring drug concentration

Gene variants that lead to longer telomeres boost brain cancer risk

Eucodis Bioscience, INVISTA to develop bio-derived processes for production of industrial chemicals

Scientists reproduce chromosomal modifications in human cells that cause certain cancer

Discovery of IDE may lead to new treatment approaches for diabetes

High dose vitamin C therapy may have positive effect on Epstein-Barr virus infection

Researchers reproduce tumor chromosomal translocations in human cells

Brown University researchers develop new biochip sensor to measure glucose levels in saliva

Researchers figure out way to disable a part of SARS virus

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