Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Researchers report a reduction in hospitalizations and deaths from SARS-CoV-2 infections during the Omicron variant-dominated wave in Malawi

Researchers conducted a serosurvey during the SARS-CoV-2 Omicron wave in Malawi.

23 Jan 2023

In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains

Researchers performed an in silico analysis to estimate the relative risks of recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

23 Jan 2023

Healthy gene found in centenarians can reverse the decline of heart performance in older people

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

23 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Study suggests Alzheimer’s disease diagnosis is associated with higher levels of soluble ACE2 in the human brain

Researchers investigated ACE2 (angiotensin-converting enzyme 2) levels among individuals with AD (Alzheimer’s disease).

23 Jan 2023

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.

23 Jan 2023

Potent small-molecule inhibitors against SARS-CoV, MERS-CoV, and SARS-CoV-2

In a recent study posted to bioRxiv* preprint server, researchers in the United States identified several potent pan-coronavirus (CoV) inhibitors.

23 Jan 2023

SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance

In a recent study posted to bioRxiv* preprint server, researchers at Ohio State University examined the degree of neutralizing antibody (nAb) evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB.1.5, CA.3.1, and CH.1.1 subvariants.

23 Jan 2023

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

20 Jan 2023

Powerful microscopy tool sheds light on the origins of arterial biomass in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rare and incurable disease of the lung arteries that causes early death.

20 Jan 2023

Study sheds light on the mechanisms behind virulence of MRSA blood stream infections

Researchers at Mount Sinai, in collaboration with researchers at New York University, have published a study in Cell Host and Microbe that sheds light on the mechanisms behind the severity, or virulence, of methicillin-resistant Staphylococcus aureus (MRSA) blood stream infections.

20 Jan 2023

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis.

20 Jan 2023

Gene editing could offer a promising solution for treating patients after a heart attack

Editing a gene that prompts a cascade of damage after a heart attack appeared to reverse this inevitable course in mice, leaving their hearts remarkably unharmed, a new study by UT Southwestern scientists showed.

20 Jan 2023

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Researchers evaluated immunoglobulin G (IgG) responses to coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccinations.

20 Jan 2023

How effective are prior SARS-CoV-2 infections and hybrid immunity against Omicron breakthrough infections?

Researchers performed a systematic review and meta-regression study to determine the breadth and duration of the protective immunity conferred by previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hybrid immunity.

20 Jan 2023

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

In this interview, News-Medical spoke to Dr. Jeremy Carlton and Professor Victoria Sanz-Moreno about their latest research into the spread of skin cancer.

20 Jan 2023

New drug target for Ewing sarcoma discovered

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults.

20 Jan 2023

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, according to a multi-institutional preclinical study led by Weill Cornell Medicine investigators.

19 Jan 2023

Study uncovers protein that kick-starts milk production after breastfeeding is over

Scientists have discovered a protein that kick-starts milk production after breastfeeding is over - something which could provide effective new targets for cancer treatments.

19 Jan 2023

Protein News and Research

Further Reading

Researchers report a reduction in hospitalizations and deaths from SARS-CoV-2 infections during the Omicron variant-dominated wave in Malawi

In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains

Healthy gene found in centenarians can reverse the decline of heart performance in older people

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Study suggests Alzheimer’s disease diagnosis is associated with higher levels of soluble ACE2 in the human brain

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

Potent small-molecule inhibitors against SARS-CoV, MERS-CoV, and SARS-CoV-2

SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

Powerful microscopy tool sheds light on the origins of arterial biomass in pulmonary arterial hypertension

Study sheds light on the mechanisms behind virulence of MRSA blood stream infections

Study reveals the mechanism through which Sirtuin 7 protein suppresses thermogenesis in mice

Gene editing could offer a promising solution for treating patients after a heart attack

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

How effective are prior SARS-CoV-2 infections and hybrid immunity against Omicron breakthrough infections?

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

New drug target for Ewing sarcoma discovered

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

Study uncovers protein that kick-starts milk production after breastfeeding is over

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