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Researchers sequence genome of Amerindian strain of the gastric bug H. pylori

An international team of researchers led by scientists at the Virginia Bioinformatics Institute at Virginia Tech have sequenced the genome of an Amerindian strain of the gastric bug Helicobacter pylori, confirming the out-of-Africa migration of this bacterial stowaway to the New World. Experiments in animals have highlighted how specific genes in the bacterial strain may be crucial to the onset of inflammation and disease.

17 Jun 2010

Trius Therapeutics reaches agreement with FDA under SPA for Phase 3 study of torezolid phosphate for ABSSSI

Trius Therapeutics, Inc. announced today that it has reached agreement with the United States Food and Drug Administration (FDA), under the Special Protocol Assessment (SPA) process, on the design of its planned Phase 3 study for the oral dosage form of torezolid phosphate for treatment of acute bacterial skin and skin structure infections (ABSSSI).

16 Jun 2010

Pervasive bacterial presence unique to contaminated drywall identified

RealTime Laboratories, LLC announced today significant new findings regarding pervasive bacterial presence unique to contaminated drywall. RealTime has identified specific bacteria found only in symptomatic drywall and not in normal domestic drywall that are viable, pervasive and produce hydrogen sulfide and reduced sulfur gases under conditions similar to those found in residences.

16 Jun 2010

Researchers discover how bacteria boost the immune system

Scientists have long known that certain types of bacteria boost the immune system. Now, Loyola University Health System researchers have discovered how bacteria perform this essential task.

15 Jun 2010

Entomologists to develop genetically engineered bacteria for killing mosquito larvae

Roughly half the world's population still lives in areas at risk of malaria transmission. Even in the United States, 1500 cases of malaria are reported annually on average.

15 Jun 2010

New bacterial strain could help in long-term cleanup of oil spills

Researchers have discovered a new strain of bacteria that can produce non-toxic, comparatively inexpensive "rhamnolipids," and effectively help degrade polycyclic aromatic hydrocarbons, or PAHs - environmental pollutants that are one of the most harmful aspects of oil spills.

14 Jun 2010

PolyMedix awarded $150,000 grant to support development of antimicrobial sutures to reduce SSIs

A new discovery may help curb surgical site infections through the use of a novel antibiotic agent that can be incorporated into sutures. SSIs are the third most common hospital-acquired infection and may be associated with severe morbidity and mortality. Since more than 60% of SSIs occur in the area of the incision, the use of sutures coated with an antibacterial agent called PolyCides, created by Radnor, PA-based PolyMedix Inc., may reduce infection rates.

14 Jun 2010

TWI launches new educational module to understand role of biofilms in chronic wound infections

The Wound Institute today announced the launch of a new educational module "Exploring Biofilms," an accredited, online course designed to help practicing wound care specialists better understand the role that biofilms play in chronic wound infections.

14 Jun 2010

Anti-infectives could circumvent the problem of antibiotic resistance

For a successful infection, bacteria must outwit the immune system of the host. To this aim, they deliver so-called virulence factors through a transport channel located in the bacterial membrane.

14 Jun 2010

sanofi pasteur congratulates Canadian Public Health Association for 100 years of leadership and service

As a longstanding partner in Canada's public health system, sanofi pasteur congratulates the Canadian Public Health Association (CPHA) for their 100 years of leadership and service to our country's public health.

11 Jun 2010

Protein IL-10 removes Escherichia coli K1 bacterium from blood and reverses brain damage

A team of researchers at Childrens Hospital Los Angeles (CHLA), along with colleagues from the Keck School of Medicine of the University of Southern California and the Universite Auvergne, France, have discovered an important role for a small, naturally occurring protein called interleukin-10 (IL-10) in removing bacteria from the blood of infected mice and reversing damage to the brain.

11 Jun 2010

Gamma interferon wakes-up sleeping stem cells to produce immune system cells to fight invading bacteria

Most of the time, the body's blood-forming (hematopoietic) stem cells remain dormant, with just a few producing blood cells and maintaining a balance among the different types.

10 Jun 2010

Texas Tech signs worldwide license agreement for metallo-beta-lactamase inhibitors with RI Scientific

Officials at Texas Tech University System's Office of Technology Commercialization announced Wednesday (June 9) the signing of an exclusive worldwide license agreement for a chemical additive called an aptamer that makes certain existing antibiotics viable against antibiotic-resistant bacteria.

10 Jun 2010

Sialidase improves nerve regrowth, motor recovery and nervous system function: Researchers

Once damaged, nerves in the spinal cord normally cannot grow back and the only drug approved for treating these injuries does not enable nerve regrowth. Publishing online this week in the Early Edition of the Proceedings of the National Academy of Sciences, researchers at the Johns Hopkins University School of Medicine show that treating injured rat spinal cords with an enzyme, sialidase, improves nerve regrowth, motor recovery and nervous system function.

10 Jun 2010

Argus Optical Mapping System for microbial whole genome analysis launched at ASM 2010 General Meeting

OpGen, Inc., a microbial genomics solutions company, announced the launch of the Argus Optical Mapping System for microbial whole genome analysis at the ASM 2010 General Meeting held in San Diego, CA May 23-27, 2010. The Argus Optical Mapping System is based on Optical Mapping Technology which generates ordered, whole genome restriction maps from single DNA molecules.

10 Jun 2010

New report compares U.S. and European funding for research related to synthetic biology

A new analysis by the Synthetic Biology Project at the Woodrow Wilson Center found that the U.S. government has spent around $430 million on research related to synthetic biology since 2005, with the Department of Energy funding a majority of the research. By comparison, the analysis indicated that the European Union and three individual European countries – the Netherlands, United Kingdom, and Germany – had spent approximately $160 million during that same period.

9 Jun 2010

DSM commences cGMP-manufacturing of Novacta's C. difficile compound

DSM BioSolutions today announced that it has entered into an agreement with Novacta Biosystems Limited, Welwyn Garden City, UK, for the process development and cGMP production of its C. difficile molecule, a new class of lantibiotic compounds.

9 Jun 2010

Health Canada approves Novartis' Menveo for prevention of meningococcal disease

Novartis Pharmaceutical Canada Inc. announced that Menveo (Meningococcal (Groups A, C, Y and W-135) Oligosaccharide CRM197 Conjugate Vaccine), a quadrivalent meningococcal conjugate vaccine was approved by Health Canada for active immunization of adolescents (11 to 18 years of age) and adults (19 to 55 years of age) to prevent invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y and W-135.

8 Jun 2010

Xenex Healthcare Services announces commercial launch of pulsed xenon room disinfection system

Xenex Healthcare Services LLC, which specializes in developing disinfection technology for healthcare facilities, today announced the commercial launch of its pulsed xenon room disinfection system and the conclusion of the Xenex system's successful trial at a leading U.S. cancer center. The Xenex system, which is now available, is the fastest, safest, and most effective method for the advanced cleaning of hospital rooms in the world today, quickly destroying all major classes of microorganisms (including viruses, bacteria and bacterial spores) without contact or chemicals.

8 Jun 2010

Researchers decipher how mast cells set immune defense on right track

In the event of an infection, the immune system releases messenger substances. These molecules can either activate immune cells to defeat invading pathogens, or inhibit them to prevent an excessive immune reaction. For this, the immune system has to decide very quickly what mixture of activating and inhibiting messenger molecules leads to a successful defence.

8 Jun 2010

Bacterial News and Research

Researchers sequence genome of Amerindian strain of the gastric bug H. pylori

Trius Therapeutics reaches agreement with FDA under SPA for Phase 3 study of torezolid phosphate for ABSSSI

Pervasive bacterial presence unique to contaminated drywall identified

Researchers discover how bacteria boost the immune system

Entomologists to develop genetically engineered bacteria for killing mosquito larvae

New bacterial strain could help in long-term cleanup of oil spills

PolyMedix awarded $150,000 grant to support development of antimicrobial sutures to reduce SSIs

TWI launches new educational module to understand role of biofilms in chronic wound infections

Anti-infectives could circumvent the problem of antibiotic resistance

sanofi pasteur congratulates Canadian Public Health Association for 100 years of leadership and service

Protein IL-10 removes Escherichia coli K1 bacterium from blood and reverses brain damage

Gamma interferon wakes-up sleeping stem cells to produce immune system cells to fight invading bacteria

Texas Tech signs worldwide license agreement for metallo-beta-lactamase inhibitors with RI Scientific

Sialidase improves nerve regrowth, motor recovery and nervous system function: Researchers

Argus Optical Mapping System for microbial whole genome analysis launched at ASM 2010 General Meeting

New report compares U.S. and European funding for research related to synthetic biology

DSM commences cGMP-manufacturing of Novacta's C. difficile compound

Health Canada approves Novartis' Menveo for prevention of meningococcal disease

Xenex Healthcare Services announces commercial launch of pulsed xenon room disinfection system

Researchers decipher how mast cells set immune defense on right track

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