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Ramelteon may help chronic insomniacs

Ramelteon, a novel investigational compound under review with the FDA for the treatment of insomnia, reduced the time it took to fall asleep and increased total sleep time in adults with chronic insomnia, according to results from a Phase 3 study presented this week at the 19th Annual Meeting of the Associated Professional Sleep Societies (APSS).

20 Jun 2005

Inactive gene may explain higher incidence of prostate cancer in African-Americans compared to Caucasians

Among African-Americans with prostate cancer, a tumor-suppressing gene called GSTP1 is inactivated at a rate 3.5 times higher than among Caucasians, according to a study conducted at the San Francisco VA Medical Center (SFVAMC).

16 Jun 2005

Neurocrine Biosciences issued new U.S. patent

Neurocrine Biosciences announced today the issuance of U.S. Patent No. 6,903,106 covering a novel polymorphic form (different crystal structure) of its proprietary compound indiplon for the treatment of insomnia.

16 Jun 2005

Scientists discover new way of bringing "bio-prospecting" out of the rainforest and into the lab

Nature is a seemingly endless storehouse of interesting - and potentially life-saving - biological molecules. But tracking down and harvesting those chemicals in their natural form can be time-consuming, expensive and unreliable.

15 Jun 2005

Promising new tuberculosis drug enters clinical trial

A promising new drug candidate that may be effective against both actively dividing and slow-growing Mycobacterium tuberculosis (M. tb) has begun testing in humans, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announced this week.

15 Jun 2005

Non-profit public-private partnership develops affordable, new drug regimens for tuberculosis

The Global Alliance for TB Drug Development (TB Alliance), a non-profit public-private partnership developing affordable, new drug regimens for tuberculosis, today announced the start of Phase I clinical trials for the lead TB drug in its pipeline, PA-824. The trials begin this month.

14 Jun 2005

Chemokine Therapeutics granted new U.S patent

Chemokine Therapeutics has announced that it has been granted U.S. Patent No. 6,875,738 relating to the use of its anti-cancer compound, CTCE-9908, in the treatment of cancer and inhibition of angiogenesis. CTCE-9908 is designed to block CXCR4, a receptor found on the surface of cancer cells.

14 Jun 2005

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

A novel compound provides long-term lowering of blood glucose levels and improves plasma lipids (fats) that are often a problem in people with type 2 diabetes -- all in a once-daily pill, according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Venom of marine cone snails may provide an improved treatment for neuropathic pain associated with diabetes

A cone snail toxin discovered by Melbourne researchers has proven to have great potential for easing pain and could provide an improved treatment for neuropathic pain associated with diabetes.

12 Jun 2005

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

An experimental drug combined with an already-popular memory-enhancing compound may further delay memory loss in patients with Alzheimer's disease and other dementias, Johns Hopkins University scientists, in collaboration with researchers from University of North Carolina, have found.

9 Jun 2005

Prototype drug shows promise in slowing replication of the virus responsible for SARS

A prototype drug created by researchers at the University of Illinois at Chicago shows promise in slowing replication of the virus responsible for severe acute respiratory syndrome, or SARS.

8 Jun 2005

Banned chemical discovered in Canadian farmed salmon

Canadian federal officials have confirmed that farmed salmon with trace amounts of a banned chemical have recently been found on store shelves.

5 Jun 2005

Novel strategy proves highly effective in killing drug-resistant multiple myeloma cells

A novel strategy devised by Dana-Farber Cancer Institute scientists has proved highly effective in killing drug-resistant multiple myeloma cells in the laboratory and could open a new form of attack on the deadly blood cancer, they report.

2 Jun 2005

Targepeutics issued new U.S patent

Targepeutics has announced the issuance of U.S. Patent No. 6,884,603 for its genetically modified, mutated Interleukin 13 (IL-13) technology platform for the treatment of malignant glioma, a brain tumor (17,500 people annually; $200 million annual market).

31 May 2005

Exposure to pharmaceutical estrogen during fetal development can permanently "reprogram" tissue in a way that determines whether tumors will develop in adulthood

Researchers at The University of Texas M. D. Anderson Cancer Center may have uncovered the reason why some people who are genetically predisposed to hormone-dependent cancers develop the disease as an adult, while others who are similarly susceptible don't.

30 May 2005

Chemicals in food packaging linked to breast cancer

Chemicals found in some food packaging materials have been shown in a new study to affect the development of breast tissue in mice, which suggests, say scientists, that women exposed to such chemicals, which mimic female hormones, may be at increased risk of breast cancer.

30 May 2005

Health officials out to zap mozzies before the peak season

Even though no cases of West Nile virus have been reported so far this year, area health officials at the Virginia Department of Health are getting a head start on mosquitoes carrying such diseases before the peak breeding season arrives.

30 May 2005

Flavonols in food, key to healthy eating?

University of Melbourne scientists may have found the secret of the fresh fruit and vegetables centred ‘Mediterranean diet’.

29 May 2005

Discovery may lead to therapies to treat the neurological disease

Opening a window to understand the molecular basis of a hereditary ataxia, Dartmouth Medical School researchers have identified an enzyme activity that is inactivated in all reported mutant forms of a disease protein. The discovery may lead to therapies to treat the neurological disease.

29 May 2005

WIN compound - a prototype drug for curing colds - is showing so much promise

An antiviral compound that wiggles its way into the common cold virus may provide one piece of the solution to halting the infection, say Purdue University scientists.

25 May 2005

Compound News and Research

Ramelteon may help chronic insomniacs

Inactive gene may explain higher incidence of prostate cancer in African-Americans compared to Caucasians

Neurocrine Biosciences issued new U.S. patent

Scientists discover new way of bringing "bio-prospecting" out of the rainforest and into the lab

Promising new tuberculosis drug enters clinical trial

Non-profit public-private partnership develops affordable, new drug regimens for tuberculosis

Chemokine Therapeutics granted new U.S patent

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

Venom of marine cone snails may provide an improved treatment for neuropathic pain associated with diabetes

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

Prototype drug shows promise in slowing replication of the virus responsible for SARS

Banned chemical discovered in Canadian farmed salmon

Novel strategy proves highly effective in killing drug-resistant multiple myeloma cells

Targepeutics issued new U.S patent

Exposure to pharmaceutical estrogen during fetal development can permanently "reprogram" tissue in a way that determines whether tumors will develop in adulthood

Chemicals in food packaging linked to breast cancer

Health officials out to zap mozzies before the peak season

Flavonols in food, key to healthy eating?

Discovery may lead to therapies to treat the neurological disease

WIN compound - a prototype drug for curing colds - is showing so much promise

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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