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Body's surveillance for cancer causing damage and response to allergies share common pathway

CANCER RESEARCH UK scientists have found that the body's surveillance for cancer causing damage and its response to allergies share a common pathway, according to research published in Science on Thursday.

1 Dec 2011

Celldex launches rindopepimut Phase 3 trial in EGFRvIII-positive glioblastoma

Celldex Therapeutics, Inc. today announced that it has launched a pivotal, randomized, double-blind, controlled Phase 3 trial of rindopepimut in patients with surgically resected epidermal growth factor variant III (EGFRvIII)-positive glioblastoma, the "ACT IV Study."

1 Dec 2011

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

The most poisonous substance on Earth - already used medically in small doses to treat certain nerve disorders and facial wrinkles - could be re-engineered for an expanded role in helping millions of people with rheumatoid arthritis, asthma, psoriasis and other diseases, scientists are reporting. Their study appears in ACS' journal Biochemistry.

1 Dec 2011

New gene therapy approach safe for patients with muscular dystrophy

Researchers at the University of North Carolina at Chapel Hill have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, the investigators found no side effects from using a "chimeric" virus to deliver replacement genes for an essential muscle protein in patients with muscular dystrophy.

1 Dec 2011

Novel nanocarbon platform shows potential for future bioelectronic implants

Researchers have demonstrated, for the first time, a graphene-based transistor array that is compatible with living biological cells and capable of recording the electrical signals they generate.

1 Dec 2011

Researchers identify first gene associated with frequent herpes-related cold sores

A team of researchers from the University of Utah and the University of Massachusetts has identified the first gene associated with frequent herpes-related cold sores.

1 Dec 2011

FDA clears Abbott's new ARCHITECT 25-OH Vitamin D assay

Abbott announced today it has received clearance from the U.S. Food and Drug Administration for a fully-automated 25-OH Vitamin D assay performed on its widely used ARCHITECT laboratory testing platform.

30 Nov 2011

Repeated soccer headers could lead to brain damage: Study

A new study suggests that frequent “heading” of soccer balls by avid amateur players may cause brain damage leading to subtle but serious declines in thinking and coordination skills.

30 Nov 2011

Elevated blood sugar levels linked with increased risk of colorectal cancer

Elevated blood sugar levels are associated with an increased risk of colorectal cancer, according to a study led by researchers at Albert Einstein College of Medicine of Yeshiva University.

30 Nov 2011

Anemia, high blood pressure linked to risk of silent strokes in children with SCD

A team of researchers from the Johns Hopkins Children's Center, Vanderbilt University and elsewhere have demonstrated that high blood pressure and anemia together put children with sickle cell disease (SCD) at serious danger for symptomless or so-called "silent" strokes, although either condition alone also signaled high risk.

30 Nov 2011

Exposure to TCE, PERC and CCI4 may increase risk of Parkinson's

A University of Kentucky faculty member is a contributing author on a new study demonstrating a connection between a common solvent chemical and Parkinson's disease. Dr. Franca Cambi of the UK Kentucky Neuroscience Institute collaborated with researchers from across the U.S. on a paper recently published in the Annals of Neurology.

29 Nov 2011

Large brains linked to regressive autism: Study

In this new study researchers at the UC Davis MIND Institute, show there are multiple biological subtypes of autism including likely differences between males and females. They looked at 114 children with autism spectrum disorder between the ages of 2 and 4 and compared them with 66 healthy children of the same age. Of the 114 with the disorder, 54% had regressive autism and 46% had non-regressive autism.

29 Nov 2011

Herbicide atrazine linked to reproductive dysfunction

An international team of researchers has reviewed the evidence linking exposure to atrazine - an herbicide widely used in the U.S. and more than 60 other nations - to reproductive problems in animals. The team found consistent patterns of reproductive dysfunction in amphibians, fish, reptiles and mammals exposed to the chemical.

29 Nov 2011

Crucial part of nervous system linked to increased risk of death from heart failure

A team of neuroscientists and anaesthetists, who have been using pioneering techniques to study how the brain regulates the heart, has identified a crucial part of the nervous system whose malfunction may account for an increased risk of death from heart failure.

29 Nov 2011

Most autoimmune diseases associated with increased risk of blood clots on the lung

Autoimmune diseases, in which the immune system attacks the body, are fairly common. Thyroid diseases, type 1 diabetes, rheumatoid arthritis, psoriasis and inflammatory bowel disease are some examples. Autoimmune diseases are associated with increased inflammation in the tissue, which in some cases is linked to an increased propensity to develop clots in the veins.

29 Nov 2011

Abusive supervision affects employee's marriage and family life

Having an abusive boss not only causes problems at work but can lead to strained relationships at home, according to a Baylor University study published online in journal, Personnel Psychology.

29 Nov 2011

Individuals with mood disorders twice as likely to have heart attacks

Depression may have more far-reaching consequences than previously believed. Recent data suggests that individuals who suffer from a mood disorder could be twice as likely to have a heart attack compared to individuals who are not depressed.

29 Nov 2011

Caregivers have stress reactions that put them at greater risk for physical health problems

When a person with mild cognitive impairment is agitated or restless, caregivers can expect to find they are more edgy as well. According to research conducted at Virginia Tech, the more a caregiver's day is disrupted by the unsettled behaviors of their loved one, the more they find themselves unable to meet or balance their own home and family work loads.

29 Nov 2011

Abbott, GSK expand collaboration to develop additional companion diagnostic test

Abbott announced today that it will expand its existing agreement with GlaxoSmithKline Biologicals S.A. to include the development of an additional companion diagnostic test in support of GSK's cancer immunotherapy research program.

29 Nov 2011

DFG approves establishment of new research training groups

To further enhance the promotion of early-career researchers in Germany, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) has approved the establishment of 16 new Research Training Groups. This decision was made by the DFG's relevant Grants Committee in Bonn.

29 Nov 2011

X linked News and Research

Body's surveillance for cancer causing damage and response to allergies share common pathway

Celldex launches rindopepimut Phase 3 trial in EGFRvIII-positive glioblastoma

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

New gene therapy approach safe for patients with muscular dystrophy

Novel nanocarbon platform shows potential for future bioelectronic implants

Researchers identify first gene associated with frequent herpes-related cold sores

FDA clears Abbott's new ARCHITECT 25-OH Vitamin D assay

Repeated soccer headers could lead to brain damage: Study

Elevated blood sugar levels linked with increased risk of colorectal cancer

Anemia, high blood pressure linked to risk of silent strokes in children with SCD

Exposure to TCE, PERC and CCI4 may increase risk of Parkinson's

Large brains linked to regressive autism: Study

Herbicide atrazine linked to reproductive dysfunction

Crucial part of nervous system linked to increased risk of death from heart failure

Most autoimmune diseases associated with increased risk of blood clots on the lung

Abusive supervision affects employee's marriage and family life

Individuals with mood disorders twice as likely to have heart attacks

Caregivers have stress reactions that put them at greater risk for physical health problems

Abbott, GSK expand collaboration to develop additional companion diagnostic test

DFG approves establishment of new research training groups

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