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New project aims to reduce animal testing for drug development

Researchers at the University of East Anglia are launching a new project to develop methods which could one-day decrease the use of rats and mice in pharmaceutical testing.

6 Dec 2013

Researchers update extensive toxicology database to track information about drugs toxic effects

Sometimes the cure can be worse than the disease. Pharmaceutical drugs are known for their potential side effects, and an important aspect of personalized medicine is to tailor therapies to individuals to reduce the chances of adverse events.

6 Dec 2013

Hummingbirds able to switch from burning glucose to fructose equally, say researchers

Hummingbird metabolism is a marvel of evolutionary engineering. These tiny birds can power all of their energetic hovering flight by burning the sugar contained in the floral nectar of their diet.

6 Dec 2013

Patient survival higher among white children than minorities post liver transplant

Novel research reveals racial and socioeconomic disparities among pediatric liver transplant patients. Findings published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, indicate that graft and patient survival was higher in white children than minorities.

6 Dec 2013

Telomerase inhibiting drug induces morphologic, molecular, clinical remissions in myelofibrosis patients

metelstat, a novel telomerase inhibiting drug, has been found to induce morphologic, molecular and clinical remissions in some patients with myelofibrosis a Mayo Clinic study has found. The results were presented today at the 2013 American Society of Hematology Annual Meeting in New Orleans.

6 Dec 2013

Study results show insulin sensitizers reduce risk of cancer in female patients with type 2 diabetes

A Cleveland Clinic-led study shows that a specific type of diabetes drug can decrease the risk of cancer in female patients with type 2 diabetes by up to 32 percent.

5 Dec 2013

IDSA released new guideline for vaccination of immunocompromised hosts

A new guideline released Thursday by the Infectious Diseases Society of America (IDSA) notes that most people with compromised immune systems are especially vulnerable to illness and should receive the flu shot and other vaccinations.

5 Dec 2013

MassBiologics gets FDA orphan drug designation for MBL-HCV1 antibody

MassBiologics of the University of Massachusetts Medical School has received an orphan drug designation from the U.S. Food and Drug Administration for MBL-HCV1, a monoclonal antibody developed to prevent hepatitis C virus recurrence in patients receiving a liver transplant.

5 Dec 2013

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

The first study of its kind, led by Melinda Sothern, PhD, CEP, Professor and Director of Behavioral and Community Health Sciences at LSU Health Sciences Center New Orleans School of Public Health, reveals that the same pro-inflammatory proteins linked to obesity and the metabolic syndrome in adults appear to protect children prior to puberty.

4 Dec 2013

LabCorp's HCV GenoSure NS3/4 test now available for Q80K polymorphism screening

Laboratory Corporation of America Holdings announced today the immediate availability of an enhanced version of its HCV GenoSure NS3/4, a drug resistance test that screens for the Q80K polymorphism. Q80K is a naturally occurring polymorphism that develops in certain strains of HCV, making the virus less susceptible to Janssen Therapeutics' OLYSIO (simeprevir), which was recently approved by the U.S. Food and Drug Administration for the treatment of certain adult patients diagnosed with genotype 1chronic hepatitis C.

3 Dec 2013

MitoQ Targeted Antioxidant Dietary Supplement now available

MitoQ Limited is excited to announce the release of their newest offering, MitoQ Targeted Antioxidant Dietary Supplement. Published studies show that the supplement, which delivers the well known antioxidant CoQ to the mitochondria (our cellular power source) better than ever before, helps repair mitochondrial dysfunction, significantly reduces oxidative damage to cells and by association supports heart, liver and brain health while assisting in the increase of energy, libido and healthy aging.

3 Dec 2013

Toshiba's new ultrasound technology depicts blood flow with more detail and accuracy

Ultrasound will be able to depict blood flow with more detail and accuracy using Toshiba America Medical Systems, Inc.'s new innovative ultrasound technology (works-in-progress).

3 Dec 2013

Research proves effectiveness of vaccine against leishmaniasis

The disease is considered endemic in the south states of Mexico. A research executed in the Autonomous University of Yucatan (UADY) has successfully proved, in test animals, the effectiveness of a vaccine that immunizes the organism against leishmaniasis, an ailment transmitted through insects very similar to mosquitos and mainly presents symptoms in the skin, liver or spleen.

3 Dec 2013

Tel Aviv University researchers discover a protein that kills bacteria

In the arms race between bacteria and modern medicine, bacteria have gained an edge. In recent decades, bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat. Scientists worry that a particularly virulent and deadly "superbug" could one day join the ranks of existing untreatable bacteria, causing a public health catastrophe comparable with the Black Death.

3 Dec 2013

Virginia Mason first to use non-invasive FibroScan technology to evaluate liver diseases

Virginia Mason today becomes the first in the Pacific Northwest to use non-invasive FibroScan technology to evaluate disease stage in patients diagnosed with liver ailments.

3 Dec 2013

Scientists transform human stem cells into functional lung and airway cells

For the first time, scientists have succeeded in transforming human stem cells into functional lung and airway cells. The advance, reported by Columbia University Medical Center researchers, has significant potential for modeling lung disease, screening drugs, studying human lung development, and, ultimately, generating lung tissue for transplantation.

2 Dec 2013

Study brings effective hepatitis C cure closer to reality

Scientists at The Scripps Research Institute have determined the most detailed picture yet of a crucial part of the hepatitis C virus, which the virus uses to infect liver cells. The new data reveal unexpected structural features of this protein and should greatly speed efforts to make an effective hepatitis C vaccine.

29 Nov 2013

World's first clinical trial to use MLC tracking system to improve prostate cancer radiotherapy treatment

Researchers and clinicians from the University of Sydney and the Northern Sydney Cancer Centre are leading a world first clinical trial using a tracking system to improve prostate cancer radiotherapy treatment.

28 Nov 2013

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

Researchers have identified the protein in malaria-causing Plasmodium parasites that is inhibited by a newly discovered class of anti-malarial compounds known as imidazopyrazines.

28 Nov 2013

UCLA researchers identify cells involved in placenta development

Dr. Hanna Mikkola and researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have identified a specific type of cell and a related cell communication pathway that are key to the successful growth of a healthy placenta. The findings could greatly bolster our knowledge about the potential causes of complications during pregnancy.

27 Nov 2013

Liver News and Research

New project aims to reduce animal testing for drug development

Researchers update extensive toxicology database to track information about drugs toxic effects

Hummingbirds able to switch from burning glucose to fructose equally, say researchers

Patient survival higher among white children than minorities post liver transplant

Telomerase inhibiting drug induces morphologic, molecular, clinical remissions in myelofibrosis patients

Study results show insulin sensitizers reduce risk of cancer in female patients with type 2 diabetes

IDSA released new guideline for vaccination of immunocompromised hosts

MassBiologics gets FDA orphan drug designation for MBL-HCV1 antibody

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

LabCorp's HCV GenoSure NS3/4 test now available for Q80K polymorphism screening

MitoQ Targeted Antioxidant Dietary Supplement now available

Toshiba's new ultrasound technology depicts blood flow with more detail and accuracy

Research proves effectiveness of vaccine against leishmaniasis

Tel Aviv University researchers discover a protein that kills bacteria

Virginia Mason first to use non-invasive FibroScan technology to evaluate liver diseases

Scientists transform human stem cells into functional lung and airway cells

Study brings effective hepatitis C cure closer to reality

World's first clinical trial to use MLC tracking system to improve prostate cancer radiotherapy treatment

Researchers identify protein in malaria that is inhibited by newly discovered anti-malarial compounds

UCLA researchers identify cells involved in placenta development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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