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Study suggests new approach to treat renal fibrosis

Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure.

16 Apr 2019

Study uncovers new biomarker for personalized cancer treatments

Cancer cells are characterized by the ability to evade apoptosis, a type of programmed cell death that allows the organism to remove damaged cells.

16 Apr 2019

Neuronal mechanisms underlying formation and retrieval of cocaine-associated memories

The environmental context in which addicts experience the rewarding effects of cocaine can readily elicit cocaine-associated memories. These memories persist long after abstinence and trigger cocaine-craving and consumption.

15 Apr 2019

Growth hormone acts directly on the brain to conserve energy when the body loses weight

Researchers at the University of São Paulo in Brazil have discovered that growth hormone (GH), which stimulates skeletal maturation and linear bone growth, as well as helping maintain tissue and organs throughout life, also acts directly on the brain to conserve energy when the body loses weight.

12 Apr 2019

Researchers identify rare SRC-1 gene variants related to human obesity

Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side.

12 Apr 2019

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher Navin Varadarajan has published in Arthritis & Rheumatology journal a first-of-its-kind study - a comprehensive profile of B cells in rheumatoid arthritis.

12 Apr 2019

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. I

12 Apr 2019

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre, have published in Cancer Cell the results of a study that shows full regression of advanced pancreatic ductal adenocarcinoma upon combined inhibition of the epidermal growth factor receptor and c-RAF kinase.

12 Apr 2019

FDA issues safety labeling changes for female sexual dysfunction treatment

The U.S. Food and Drug Administration today issued a safety labeling change order to Sprout Pharmaceuticals for their drug, Addyi (flibanserin), that requires the company to revise important safety information that women and their health care professionals need to have when considering use of the drug.

12 Apr 2019

Researchers discover pathway contributing to fatty liver disease

Researchers from Karolinska Institutet have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

11 Apr 2019

Eight-year study identifies potential new way to treat extreme childhood food allergy

An eight-year hunt for the cells that drive the extreme childhood food allergy eosinophilic esophagitis has identified a potential new way to treat the disease while also raising questions about a dietary supplement often taken to reduce bowel inflammation.

9 Apr 2019

Scientists identify receptor responsible for bitter taste of Epsom salt

A team of scientists headed by Maik Behrens from the Leibniz-Institute for Food Systems Biology at the Technical University of Munich has identified the receptor responsible for the bitter taste of various salts. These include medically used Epsom salt.

8 Apr 2019

Scientists visualize immune cells fighting blood cancer for the first time

When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease.

8 Apr 2019

Study reveals immune evasion strategy developed by cytomegaloviruses

Owl monkey cytomegalovirus produces a decoy molecule A43 to evade detection and destruction by immune cells in their hosts, according to a study published April 4 in the open-access journal PLOS Pathogens by Ana Angulo of the University of Barcelona, and colleagues.

8 Apr 2019

Researchers identify gut protein essential for neonatal mice to fight infections

Scientists have identified a protein critical to the immune system development and antibody production in mice, which could contribute to understanding the gut defense mechanism in infants.

8 Apr 2019

Celltrion and iProgen Biotech announce partnership for development of novel ADCs

On April 8, Celltrion and the Canada-based iProgen Biotech Inc. announced to agree to partner for the development of novel ADCs against validated antibody targets, including HER2 and CD20.

8 Apr 2019

Scientists solve mystery surrounding mechanical forces that influence blood clotting

Researchers at the University of Sydney have used biomechanical engineering techniques to unlock the mystery surrounding the mechanical forces that influence blood clotting.

5 Apr 2019

FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

Study: Pathogenetic downregulation of adenosine linked to restless leg syndrome

Researchers have identified a common mechanism implicating adenosine in the cause of restless leg syndrome symptoms — the periodic limb movements characteristic of RLS and the state of enhanced arousal that both disrupt sleep.

4 Apr 2019

UCR study: Surgery associated with higher survival of patients with HER2-positive stage 4 breast cancer

A student at the University of California, Riverside, presented research results at the annual meeting of the American Association for Cancer Research, or AACR, in Atlanta showing that surgery is associated with higher survival rates for patients with HER2-positive stage 4 breast cancer compared with those who did not undergo surgery.

3 Apr 2019

Receptor News and Research

Study suggests new approach to treat renal fibrosis

Study uncovers new biomarker for personalized cancer treatments

Neuronal mechanisms underlying formation and retrieval of cocaine-associated memories

Growth hormone acts directly on the brain to conserve energy when the body loses weight

Researchers identify rare SRC-1 gene variants related to human obesity

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

Combined inhibition of EGFR and c-RAF kinase shows regression of most aggressive pancreatic cancer

FDA issues safety labeling changes for female sexual dysfunction treatment

Researchers discover pathway contributing to fatty liver disease

Eight-year study identifies potential new way to treat extreme childhood food allergy

Scientists identify receptor responsible for bitter taste of Epsom salt

Scientists visualize immune cells fighting blood cancer for the first time

Study reveals immune evasion strategy developed by cytomegaloviruses

Researchers identify gut protein essential for neonatal mice to fight infections

Celltrion and iProgen Biotech announce partnership for development of novel ADCs

Scientists solve mystery surrounding mechanical forces that influence blood clotting

FDA extends indication of metastatic breast cancer treatment to include male patients

Study: Pathogenetic downregulation of adenosine linked to restless leg syndrome

UCR study: Surgery associated with higher survival of patients with HER2-positive stage 4 breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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