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New computer program developed by TGen lights up cancer-causing genetic mutations

By conjuring the spell "Lumos!" wizards in the mythical world of Harry Potter could light up the tip of their magic wands and illuminate their surroundings. So, too, does LumosVar, a computer program developed by the Translational Genomics Research Institute, "light up" cancer-causing genetic Var-ients, or mutations, illuminating how physicians might best treat their patients.

21 Mar 2019

Researchers discover possible new therapeutic strategy for pancreatic cancer

Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a possible new therapeutic strategy using two types of drug inhibitors at once to treat one of the world's deadliest cancers.

21 Mar 2019

Active substance from plant could turn into a ray of hope against eye tumors

An active substance that has been known for 30 years could unexpectedly turn into a ray of hope against eye tumors.

20 Mar 2019

Breast cancer relapse predictor tool may soon be a reality

Researchers have developed a tool by which they can predict accurately the time when breast cancer is likely to return.

20 Mar 2019

Umass Amherst food scientist honored with 2019 Young Scientist Research Award

Guodong Zhang, assistant professor of food science at the University of Massachusetts Amherst, is being honored with the 2019 Young Scientist Research Award from the American Oil Chemists' Society.

20 Mar 2019

Combined immunosuppression may be effective, safe in treating older patients with Crohn’s disease

Combining medications that suppress the immune system has been successful in treating young patients with Crohn's disease, but some physicians have been reluctant to use this strategy in older patients because of concerns about safety.

20 Mar 2019

Researchers discover previously unknown mechanism by which cells can sense oxygen

Researchers from the University of Oulu and Harvard University have found a previously unknown mechanism by which cells in the body sense oxygen. Lack of oxygen had a direct influence on the functioning of genes, and prevented cell differentiation.

20 Mar 2019

New analysis reveals precision oncology insights for colorectal cancer

Next-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to different survival and treatment outcomes in an analysis led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher.

20 Mar 2019

Cholesterol lowering drug can also help treat cancer-associated cachexia

Brazilian researchers have discovered that a drug regularly prescribed to control cholesterol can also be used to treat cachexia, or wasting syndrome, a condition characterized by rapid weight loss and muscle atrophy associated with extreme physical weakness.

19 Mar 2019

New class of drugs could help treat patients diagnosed with ovarian cancer

A team of researchers across The University of Manchester have shown that a new class of drugs are able to stop ovarian cancer cells growing.

19 Mar 2019

GARP protein can be a potential target for immunotherapy against colorectal cancer

Colorectal cancer is the third leading cause of cancer-related deaths in both men and women. Despite significant advances in therapies for this particular cancer, the five-year survival rate is 12 percent, according to the American Cancer Society.

19 Mar 2019

Prophylactic cranial irradiation used as standard approach for patients with NSCLC

Prophylactic cranial irradiation, a technique used to prevent the clinical development of brain metastases, is established as a standard approach for many patients with small cell lung cancer after initial therapy.

19 Mar 2019

Hormonal treatment associated with depression in men with prostate cancer

Men who receive anti-hormonal treatment after having their prostate removed are 80% more likely to suffer from depression than men who don't receive this treatment. This leads researchers to suggest that patients receiving androgen deprivation therapy should be monitored for post-surgical depression.

18 Mar 2019

USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer

Researchers at the George Washington University Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications.

15 Mar 2019

Key discoveries could shed light on retinoblastoma

Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age and accounts for approximately 4% of childhood cancers. If not diagnosed early, retinoblastoma may result in loss of one or both eyes and can be fatal.

15 Mar 2019

Study describes epigenetic loss that changes how cells obtain energy from cancer

It has been known for decades that cancer cells have an altered metabolism and it is seen in several biochemical pathways and in particular, in the way they get energy for their survival.

15 Mar 2019

Molecular patterns could help predict relapse risk in breast cancer patients

The genetic and molecular make-up of individual breast tumors holds clues to how a woman’s disease could progress, including the likelihood of it coming back after treatment, and in what time frame, according to a Cancer Research UK-funded study published in Nature today (Wednesday).

14 Mar 2019

Oral bacteria in pancreas associated with tumor severity

The presence of oral bacteria in so-called cystic pancreatic tumours is associated with the severity of the tumour, a study by researchers at Karolinska Institutet in Sweden published in the journal Gut reports. It is hoped that the results can help to improve diagnosis and treatment of pancreatic cancer.

14 Mar 2019

Free fatty acids in the blood linked with elevated risk of breast cancer in obese women

Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women's elevated risk of developing breast cancer after menopause.

14 Mar 2019

Study: Early-life exposure to microbiota inhibits colon cancer in adulthood

Exposure to microbiota, or microorganisms such as bacteria, in the early stages of life plays a crucial role in establishing optimal conditions in the intestine that inhibit the development of colon cancer in adulthood, according to a study led by Georgia State University.

14 Mar 2019

Tumor News and Research

New computer program developed by TGen lights up cancer-causing genetic mutations

Researchers discover possible new therapeutic strategy for pancreatic cancer

Active substance from plant could turn into a ray of hope against eye tumors

Breast cancer relapse predictor tool may soon be a reality

Umass Amherst food scientist honored with 2019 Young Scientist Research Award

Combined immunosuppression may be effective, safe in treating older patients with Crohn’s disease

Researchers discover previously unknown mechanism by which cells can sense oxygen

New analysis reveals precision oncology insights for colorectal cancer

Cholesterol lowering drug can also help treat cancer-associated cachexia

New class of drugs could help treat patients diagnosed with ovarian cancer

GARP protein can be a potential target for immunotherapy against colorectal cancer

Prophylactic cranial irradiation used as standard approach for patients with NSCLC

Hormonal treatment associated with depression in men with prostate cancer

USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer

Key discoveries could shed light on retinoblastoma

Study describes epigenetic loss that changes how cells obtain energy from cancer

Molecular patterns could help predict relapse risk in breast cancer patients

Oral bacteria in pancreas associated with tumor severity

Free fatty acids in the blood linked with elevated risk of breast cancer in obese women

Study: Early-life exposure to microbiota inhibits colon cancer in adulthood

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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