Genes News and Research

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Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and late 1800s, respectively, immunotherapy has more recently emerged as a viable and successful approach to cancer treatment.

18 Sep 2020

Adaptations found in RNA secondary structure in genes of two proteins of SARS-CoV-2

To investigate mutations in coronaviruses, a new study by scientists at Duke University and published on the preprint server bioRxiv, used a computational methodology, adaptiPhy, which identifies extra nucleotide substitutions in certain parts of the viral genome compared to mutations that have no effect on the genome.

18 Sep 2020

Ineffective immune responses may be responsible for COVID-19 mortality rates in men and the elderly

News-Medical speaks to Dr. Nicole Lieberman about her latest research that discovered delayed immune responses may affect COVID-19 mortality rates.

18 Sep 2020

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

"Do not erase." "Recycle me." "Free to a good home." Humans post these signs to indicate whether something has value or not, whether it should be disposed of or not.

18 Sep 2020

Animal data supports efficacy of baricitinib vs SARS-COV-2

The high burden of disease caused by the COVID-19 pandemic has led to much research on effective ways to mitigate the health, social, and economic impact of the spread of the infection. A recent study published on the preprint server bioRxiv* in September 2020 reports on the characteristics of the drug baricitinib when used as monotherapy to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Strong causative link between smoking and bleeding in the brain

A decade ago, in a Nordic Twin Cohort study involving 79,664 twins from Denmark, Finland, and Sweden, researchers looked at risk factors of SAH other than genes.

17 Sep 2020

Australian stinging tree could pave way for novel painkillers

Australia is well known for having many of the world's most venomous creatures, ranging from snakes, spiders, jellyfish, centipedes, fish, ticks, bees, and ants. 21 of the 25 most venomous snakes in the world are all from Australia. The country is also home to dangerous plants, like the Australian stinging tree.

17 Sep 2020

New methods help to accurately identify cancers’ hidden genetic losses, duplications

Understanding the specific mutations that contribute to different forms of cancer is critical to improving diagnosis and treatment.

17 Sep 2020

Time-restricted feeding does not influence the muscle’s core clock, study finds

For the first time, scientists have studied the early effects of time-restricted feeding on the daily periodic oscillations of metabolites and genes in muscle, and metabolites in blood.

17 Sep 2020

Scientists identify new genetic cause of syndromic microcephaly

Greenwood Genetic Center researchers, in collaboration with scientists from Belgium, Spain, and Italy, have confirmed that variants in LMNB1 cause syndromic microcephaly with variable short stature, intellectual disability, and other neurological symptoms.

17 Sep 2020

Study finds potential target for migraine therapy

Migraines affect millions of people worldwide, often lasting days and severely disrupting lives. More than simply super-intense headaches, some migraines actually result from pathological excitation of neurons in the brain.

17 Sep 2020

Study provides new insight into the evolution of limb regeneration in lungfish and other species

For most vertebrates, losing a limb is permanent, but a lucky few species -- such as salamanders and tadpoles -- have the ability to completely regrow complex body parts.

17 Sep 2020

UC Davis uses microneedles to deliver gene therapy for retinal diseases

A novel approach to delivering gene therapy for retinal diseases eliminates the need for complex eye surgery and treats more damaged cells than existing methods, a team of UC Davis physicians and veterinary eye specialists has found.

16 Sep 2020

Study provides valuable insights on effects of APOE gene on health and disease

From Alzheimer's to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging these predispositions, showing that some of the genes traditionally labelled as 'bad' are not always what they seem.

16 Sep 2020

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome -- the trillions of microbes living inside the digestive system that regulate various bodily functions.

16 Sep 2020

UIC receives $4.5 million to study how adolescent binge drinking affects adult behavior

The University of Illinois Chicago has received $4.5 million in continuation funding from the National Institute on Alcohol Abuse and Alcoholism to support the UIC site of the national Neurobiology of Adolescent Drinking in Adulthood, or NADIA, consortium.

15 Sep 2020

Survey finds many women are avoiding pregnancy due to severe migraine

A survey of 607 women who suffer from severe migraine found twenty percent of the respondents are currently avoiding pregnancy because of their migraines.

15 Sep 2020

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows.

15 Sep 2020

Researchers identify specific potential therapeutic targets for aggressive form of pancreatic cancer

A team of researchers led by Mayo Clinic and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified specific potential therapeutic targets for the most aggressive and lethal form of pancreatic cancer.

15 Sep 2020

Central nervous system immune responses to COVID-19

A recent study published on the preprint server bioRxiv by scientists from Yale School of Medicine, University of California, Yale School of Public Health, Yale University, and Howard Hughes Medical Institute examined the impact of SARS-CoV-2 infection on the central nervous system.

14 Sep 2020

Genes News and Research

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

Adaptations found in RNA secondary structure in genes of two proteins of SARS-CoV-2

Ineffective immune responses may be responsible for COVID-19 mortality rates in men and the elderly

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

Animal data supports efficacy of baricitinib vs SARS-COV-2

Strong causative link between smoking and bleeding in the brain

Australian stinging tree could pave way for novel painkillers

New methods help to accurately identify cancers’ hidden genetic losses, duplications

Time-restricted feeding does not influence the muscle’s core clock, study finds

Scientists identify new genetic cause of syndromic microcephaly

Study finds potential target for migraine therapy

Study provides new insight into the evolution of limb regeneration in lungfish and other species

UC Davis uses microneedles to deliver gene therapy for retinal diseases

Study provides valuable insights on effects of APOE gene on health and disease

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

UIC receives $4.5 million to study how adolescent binge drinking affects adult behavior

Survey finds many women are avoiding pregnancy due to severe migraine

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

Researchers identify specific potential therapeutic targets for aggressive form of pancreatic cancer

Central nervous system immune responses to COVID-19

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