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Aligned approach to advanced bladder cancer treatment very much needed, study says

New study, involving eight Italian research centres, concluded that an aligned approach to the treatment of advanced bladder cancer is much needed, while confirming previously published results on survival estimates of associated salvage therapies.

18 Nov 2013

Study suggests potential new treatment for seizures

A study out today in the journal Nature Medicine suggests a potential new treatment for the seizures that often plague children with genetic metabolic disorders and individuals undergoing liver failure. The discovery hinges on a new understanding of the complex molecular chain reaction that occurs when the brain is exposed to too much ammonia.

17 Nov 2013

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Researchers at Case Western Reserve University and Cleveland Clinic Lerner Research Institute have discovered recent genetic mutations in a parasite that causes over 100 million cases of malaria annually-changes that may render tens of millions of Africans who had been considered resistant, susceptible to infection.

16 Nov 2013

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Provocative new research shows that the Plasmodium vivax parasite, responsible for nearly 20 million cases of malaria in 2010, may be "rapidly evolving" to overcome the natural resistance conferred by a blood type found in millions of Africans, scientists reported today at the annual meeting of the American Society of Tropical Medicine and Hygiene.

16 Nov 2013

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research from postdoctoral fellow Lick Lai in the lab of USC scientist Andy McMahon published in Proceedings of the National Academy of Sciences (PNAS) sheds light on how this important protein keeps people organized on a basic level by promoting orderly skeletal growth and preventing skeletal tumors.

15 Nov 2013

Annexin A5 protein may have therapeutic potential for treatment of sepsis

Sepsis is the leading cause of in-hospital death and there is no specific treatment for it. Now, research led by Dr. Qingping Feng of Western University (London, Canada) suggests a protein called recombinant human annexin A5 may have therapeutic potential for the treatment of this disease. The paper is published in advance, online in Critical Care Medicine.

15 Nov 2013

Cardiologists question FDA recommendations on genetic testing before taking Plavix

Which antiplatelet medication is best after a coronary stent? The costly and potential life-or-death question lingers after most of the 600,000 angioplasties performed every year in the United States. The answer may lie in your genes, but professional cardiovascular societies and many working cardiologists question the U.S. Food and Drug Administration's recent recommendation that patients undergo genetic testing before taking Plavix (clopidogrel bisulfate).

14 Nov 2013

Researchers shed light on how and when immune system forms

Researchers at Lund University have shed light on how and when the immune system is formed, raising hope of better understanding various diseases in children, such as leukaemia.

13 Nov 2013

Promethera Biosciences completes patient enrolment for first clinical trial of HepaStem

Promethera Biosciences, a Belgian biotechnology company developing Promethera HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announces today the completion of patient enrolment for its first clinical trial.

12 Nov 2013

Livers from donors with pre-hospital cardiac arrest considered for transplant

Researchers from the U.K. suggest that using organs from donors after circulatory death (DCD) who also suffered a previous cardiac arrest out of the hospital environment could expand the pool of available livers for transplant.

11 Nov 2013

CTCA doctor presents cutting-edge treatments for cancer patients to medical colleagues

Walter Quan, Jr., MD Chief of Medical Oncology and Director of Immunotherapy at Cancer Treatment Centers of America- Western Regional Medical Center is presenting new findings that are showing a major benefit to cancer patients.

11 Nov 2013

Genovate, ScinoPharm to jointly develop new-generation oral Hepatitis B drug Livepro

Genovate Biotechnology Co. Ltd. and ScinoPharm Taiwan Ltd. announced today that they have jointly developed the highly potent oral generic drug Livepro (Entecavir), representing a new generation of drugs for the treatment of Hepatitis B. It is expected to be commercially available by the end of the year in Taiwan, accounting for more than NT$2 billion (US$70 million) worth of market opportunity.

11 Nov 2013

FOXO3 transcription factor may protect against alcohol-induced liver injury

New data suggest that the transcription factor FOXO3 may protect against alcohol-induced liver injury. Researchers determined that alcohol given to mice deficient in FOXO3 caused severe liver injury resembling human alcoholic hepatitis.

11 Nov 2013

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

A team of scientists that includes Saint Louis University researchers has identified a new way to intervene in the molecular and cellular cascade that causes fibrosis - a condition where the body's natural process of forming scars for wound healing goes into overdrive and causes diseases.

11 Nov 2013

TGen-led study reveals viable target to prevent spread of brain cancer

A cellular pathway interaction known as TWEAK-Fn14, often associated with repair of acute injuries, also is a viable target for drug therapy that could prevent the spread of cancer, especially brain cancer, according to a study led by the Translational Genomics Research Institute.

11 Nov 2013

Tissue scarring may help develop new treatments for patients with damaged organs

Patients with damaged organs could be helped by new treatments after scientists have discovered how tissues scar.

10 Nov 2013

Scientist shows how immune system 'attacks' liver cells during hepatitis by using JunB gene

Viral infections are the primary cause of liver inflammation or hepatitis, affecting hundreds of millions of people all over the world, and they represent a public health problem worldwide.

10 Nov 2013

Breast cancer drug appears to protect cells against UV radiation, inflammation

Exemestane, a synthetic steroid drug widely prescribed to fight breast cancers that thrive on estrogens, not only inhibits the production of the hormone, but also appears to protect cells throughout the body against damage induced by UV radiation, inflammation and other assaults, according to results of research by Johns Hopkins scientists.

8 Nov 2013

Life-saving bone marrow transplants may also cure peanut allergies

Not only can bone marrow transplants be life-saving for children with acute lymphocytic leukemia, they may also cure peanut allergies. According to research presented during the American College of Allergy, Asthma and Immunology's Annual Scientific Meeting, a 10-year-old boy no longer had a peanut allergy after undergoing a bone marrow transplant.

8 Nov 2013

GHIT Fund makes new investments in potential treatments for malaria, tuberculosis and Chagas disease

The Global Health Innovative Technology Fund, a new public health partnership that is bringing Japanese know-how and investment to the global fight against infectious diseases, announced today grants of US$5.7 million to six global partnerships working on innovative drugs and vaccines against malaria, tuberculosis and Chagas disease.

8 Nov 2013

Liver News and Research

Aligned approach to advanced bladder cancer treatment very much needed, study says

Study suggests potential new treatment for seizures

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Annexin A5 protein may have therapeutic potential for treatment of sepsis

Cardiologists question FDA recommendations on genetic testing before taking Plavix

Researchers shed light on how and when immune system forms

Promethera Biosciences completes patient enrolment for first clinical trial of HepaStem

Livers from donors with pre-hospital cardiac arrest considered for transplant

CTCA doctor presents cutting-edge treatments for cancer patients to medical colleagues

Genovate, ScinoPharm to jointly develop new-generation oral Hepatitis B drug Livepro

FOXO3 transcription factor may protect against alcohol-induced liver injury

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

TGen-led study reveals viable target to prevent spread of brain cancer

Tissue scarring may help develop new treatments for patients with damaged organs

Scientist shows how immune system 'attacks' liver cells during hepatitis by using JunB gene

Breast cancer drug appears to protect cells against UV radiation, inflammation

Life-saving bone marrow transplants may also cure peanut allergies

GHIT Fund makes new investments in potential treatments for malaria, tuberculosis and Chagas disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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