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Preclinical data shows combination immunotherapy could suppress tumor growth in the liver

Even as overall cancer incidence and mortality decrease in the United States, the number of people diagnosed with liver cancer is on the rise.

14 Mar 2019

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, effectively killing cancer cells.

14 Mar 2019

Harmless purple bacteria can visualize aspects of tumor heterogeneity

Cancer presents an ongoing challenge for physicians, particularly in the diagnosis and treatment of the disease. This is, amongst other things, due to tumor heterogeneity.

14 Mar 2019

Increased stress hormones accelerate breast cancer metastasis

It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones.

14 Mar 2019

PNAS publishes results of pilot study for early detection of liver cancer

Today, Proceedings of the National Academy of Sciences published the results of a pilot study for early detection of liver cancer in a cohort of HBV carriers, who are at risk for developing this disease.

13 Mar 2019

New risk model can predict survival of non-metastatic prostate cancer patients

A new risk model, easily accessible on a web interface, can predict the survival of non-metastatic prostate cancer patients, as well as the effect of different treatment approaches on survival.

13 Mar 2019

Scientists find highly promising therapeutic target for leukemia

Cancer cells consume sugar at a higher rate than healthy cells, but they're also hungry for amino acids, the building blocks of proteins and other biomolecules.

13 Mar 2019

New nuclear medicine tracers make it easier to diagnose and treat cancer

Researchers have identified two new nuclear medicine tracers that make it easier to diagnose and potentially treat cancer.

12 Mar 2019

Managing nontraditional risk factors to improve outcomes after cancer surgery

In a study of 142 patients preparing for cancer surgery, Johns Hopkins Medicine researchers say they have evidence that psychological or social risk factors such as depression, limited resilience and lack of emergency resources along with standard medical risk factors such as high blood pressure or diabetes are linked with higher risks of surgical complications.

12 Mar 2019

Researchers develop statistical approach to reveal elusive cancer-promoting genes

Australian and US researchers have developed a way to discover elusive cancer-promoting genes, and have already identified one that appears to promote aggressive breast cancers.

11 Mar 2019

New imaging technology could help find tiny tumors

Many types of cancer could be more easily treated if they were detected at an earlier stage. MIT researchers have now developed an imaging system, named "DOLPHIN," which could enable them to find tiny tumors, as small as a couple of hundred cells, deep within the body.

7 Mar 2019

Researchers develop 'snap freezing' apparatus to cool biopsy even faster

For rapid freezing of a biopsy taken from a patient, for cancer research for example, the standard procedure is using liquid nitrogen.

7 Mar 2019

CT scans used in cancer diagnostics can provide valuable clues to preventing heart problems

An imaging procedure commonly performed before starting cancer treatment can provide valuable clues about a patient's risk for heart problems in the months and years after treatment.

7 Mar 2019

Nuclear medicine imaging assesses melanoma patients' response to immunotherapy

Nuclear medicine imaging with PET/CT can monitor the effectiveness of immunotherapy treatment for metastatic melanoma and predict outcome. In this way, a patient's therapy can be more effectively tailored to his or her personal response.

6 Mar 2019

Colon cancer could be made more aggressive by common oral bacteria

Scientists have identified a common oral bacterium that accelerates colon cancer growth. The discovery could pave the way for new treatments.

5 Mar 2019

Genomics could guide treatment for pancreatic cancer patients

Pancreatic cancer is a grim diagnosis, with a five-year survival rate of less than 9 percent. To improve those odds, researchers at UPMC and the University of Pittsburgh School of Medicine sought genetic signatures in the largest study of its kind that could be used to better match drugs to patients and for early detection.

5 Mar 2019

Radiation after surgery in children with ependymoma nearly triples survival rate

Radiation immediately following surgery in children with ependymoma, the third most common pediatric brain tumor, can nearly triple survival.

5 Mar 2019

New clinical genomic testing helps identify mutations that drive childhood melanoma

Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma.

5 Mar 2019

Researchers find how common oral bacteria accelerates growth of colon cancer

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum -- a common oral bacteria often implicated in tooth decay -- accelerates the growth of colon cancer. The study was published online in the journal EMBO Reports.

4 Mar 2019